PMID- 30965384
OWN - NLM
STAT- Publisher
LR  - 20190409
IS  - 1365-2133 (Electronic)
IS  - 0007-0963 (Linking)
DP  - 2019 Apr 9
TI  - Benefits of a brief psychological intervention targeting fear of cancer
      recurrence in people at high risk of developing another melanoma: 12-month
      follow-up results of a randomised controlled trial.
LID - 10.1111/bjd.17990 [doi]
AB  - BACKGROUND: People with melanoma want and need effective interventions for living
      with fear of cancer recurrence (FCR). OBJECTIVE: This study reports the 12-month 
      outcomes of a brief, psychological intervention designed to reduce FCR in people 
      at high risk of developing another primary melanoma compared to usual care.
      METHODS: In this two-arm randomized controlled trial, adults previously diagnosed
      with Stage 0, I or II melanoma were randomly allocated to the intervention (n=80)
      or control (usual care) arm (n=84). The intervention comprised a 76-page
      psycho-educational resource and three individually-tailored, telephone-based
      sessions with a psychologist, scheduled at specific time-points around
      participants' dermatological appointments. The primary outcome was the level of
      self-reported fear of new or recurrent melanoma assessed at 12 months
      post-intervention using the Severity subscale of the Fear of Cancer Recurrence
      Inventory (FCRI). RESULTS: Compared to the control arm, the intervention group
      reported significantly lower FCR at 12 months post-intervention; the
      between-group mean difference was -1.41 for FCR severity (95% CI -2.6 to -0.2;
      p=0.02), and -1.32 for FCR triggers (95% CI -2.6 to -0.02; p=0.04). The odds
      ratio for FCR severity scores >/=13 (54% intervention, 63% control) was 0.59 (95%
      CI 0.30 to 1.14, p=0.12). There were no differences between groups in secondary
      outcomes, such as anxiety, depression or health-related quality of life.
      CONCLUSIONS: The previously-reported 6-month benefits of this brief,
      patient-centered psychological intervention in reducing fear of cancer recurrence
      were found to continue 12-months post-intervention, with no known adverse
      effects, supporting implementation as part of routine melanoma care. This article
      is protected by copyright. All rights reserved.
CI  - This article is protected by copyright. All rights reserved.
FAU - Dieng, M
AU  - Dieng M
AD  - NHMRC Clinical, Trials Centre, The University of Sydney, NSW, Australia.
AD  - Cancer Epidemiology and Prevention Research, Sydney School of Public Health, The 
      University of Sydney, NSW, Australia.
FAU - Morton, R L
AU  - Morton RL
AD  - NHMRC Clinical, Trials Centre, The University of Sydney, NSW, Australia.
FAU - Costa, D S J
AU  - Costa DSJ
AD  - Pain Management Research Institute, University of Sydney at Royal North Shore
      Hospital, NSW, Australia.
FAU - Butow, P N
AU  - Butow PN
AD  - Psycho-oncology Co-operative Research Group, School of Psychology, University of 
      Sydney, NSW, Australia.
FAU - Menzies, S W
AU  - Menzies SW
AD  - Discipline of Dermatology, Sydney Medical School, The University of Sydney,
      Australia.
AD  - The Sydney Melanoma Diagnostic Centre, Royal Prince Alfred Hospital, NSW,
      Australia.
FAU - Lo, S
AU  - Lo S
AD  - Melanoma Institute Australia, The University of Sydney, Australia.
AD  - Institute for Research and Medical Consultations, University of Dammam, Dammam,
      KSA.
FAU - Mann, G J
AU  - Mann GJ
AD  - Melanoma Institute Australia, The University of Sydney, Australia.
AD  - Centre for Cancer Research, Westmead Institute for Medical Research, University
      of Sydney, Australia.
FAU - Cust, A E
AU  - Cust AE
AD  - Cancer Epidemiology and Prevention Research, Sydney School of Public Health, The 
      University of Sydney, NSW, Australia.
AD  - Melanoma Institute Australia, The University of Sydney, Australia.
FAU - Kasparian, N A
AU  - Kasparian NA
AD  - Melanoma Institute Australia, The University of Sydney, Australia.
AD  - Discipline of Paediatrics, School of Women's and Children's Health, UNSW
      Medicine, The University of New South Wales, Sydney, NSW, Australia.
AD  - Harvard Medical School, Boston, Massachusetts, United States.
LA  - eng
PT  - Journal Article
DEP - 20190409
PL  - England
TA  - Br J Dermatol
JT  - The British journal of dermatology
JID - 0004041
OTO - NOTNLM
OT  - Melanoma
OT  - cancer
OT  - fear of cancer recurrence
OT  - psychoeducation
OT  - psychological intervention
EDAT- 2019/04/10 06:00
MHDA- 2019/04/10 06:00
CRDT- 2019/04/10 06:00
PHST- 2019/04/10 06:00 [entrez]
PHST- 2019/04/10 06:00 [pubmed]
PHST- 2019/04/10 06:00 [medline]
AID - 10.1111/bjd.17990 [doi]
PST - aheadofprint
SO  - Br J Dermatol. 2019 Apr 9. doi: 10.1111/bjd.17990.