PMID- 30801473
STAT- In-Data-Review
LR  - 20190225
IS  - 1873-233X (Electronic)
IS  - 0029-7844 (Linking)
VI  - 133
IP  - 3
DP  - 2019 Mar
TI  - ACOG Practice Bulletin No. 207: Thrombocytopenia in Pregnancy.
PG  - e181-e193
LID - 10.1097/AOG.0000000000003100 [doi]
AB  - Obstetricians frequently diagnose thrombocytopenia in pregnant women because
      platelet counts are included with automated complete blood cell counts obtained
      during routine prenatal screening (). Although most U.S. health care providers
      are trained using U.S. Conventional Units, most scientists, journals, and
      countries use Systeme International (SI) units. The laboratory results reported
      in U.S. Conventional Units can be converted to SI Units or vice versa by using a 
      conversion factor. Given the conversion factor is 1.0, when converting from
      10/muL to 10/L the platelet "count" does not seemingly change. Thrombocytopenia, 
      defined as a platelet count of less than 150 x 10/L, is common and occurs in
      7-12% of pregnancies at the time of delivery (). Thrombocytopenia can result from
      a variety of physiologic or pathologic conditions, several of which are unique to
      pregnancy. Some causes of thrombocytopenia are serious medical disorders that
      have the potential for maternal and fetal morbidity. In contrast, other
      conditions, such as gestational thrombocytopenia, are benign and pose no maternal
      or fetal risks. Because of the increased recognition of maternal and fetal
      thrombocytopenia, there are numerous controversies about obstetric management of 
      this condition. Clinicians must weigh the risks of maternal and fetal bleeding
      complications against the costs and morbidity of diagnostic tests and invasive
      interventions. This Practice Bulletin is a targeted revision to reflect limited
      changes to information about new estimates for thrombocytopenia in pregnancy and 
      the risk of recurrence of fetal-neonatal alloimmune thrombocytopenia in
      subsequent pregnancies, and to provide new information on the level of
      thrombocytopenia that permits regional anesthesia.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Obstet Gynecol
JT  - Obstetrics and gynecology
JID - 0401101
EDAT- 2019/02/26 06:00
MHDA- 2019/02/26 06:00
CRDT- 2019/02/26 06:00
PHST- 2019/02/26 06:00 [entrez]
PHST- 2019/02/26 06:00 [pubmed]
PHST- 2019/02/26 06:00 [medline]
AID - 10.1097/AOG.0000000000003100 [doi]
AID - 00006250-201903000-00043 [pii]
PST - ppublish
SO  - Obstet Gynecol. 2019 Mar;133(3):e181-e193. doi: 10.1097/AOG.0000000000003100.