PMID- 30710526
OWN - NLM
STAT- MEDLINE
DCOM- 20190513
LR  - 20190513
IS  - 1528-0012 (Electronic)
IS  - 0016-5085 (Linking)
VI  - 156
IP  - 6
DP  - 2019 May
TI  - RNA Analysis Identifies Pathogenic Duplications in MSH2 in Patients With Lynch
      Syndrome.
PG  - 1924-1925.e4
LID - S0016-5085(19)30343-9 [pii]
LID - 10.1053/j.gastro.2019.01.248 [doi]
FAU - Conner, Blair R
AU  - Conner BR
AD  - Ambry Genetics, Aliso Viejo, California.
FAU - Hernandez, Felicia
AU  - Hernandez F
AD  - Ambry Genetics, Aliso Viejo, California.
FAU - Souders, Beth
AU  - Souders B
AD  - Ambry Genetics, Aliso Viejo, California.
FAU - Landrith, Tyler
AU  - Landrith T
AD  - Ambry Genetics, Aliso Viejo, California.
FAU - Boland, C Richard
AU  - Boland CR
AD  - Division of Gastroenterology, University of California, San Diego, California.
FAU - Karam, Rachid
AU  - Karam R
AD  - Ambry Genetics, Aliso Viejo, California. Electronic address: rkaram@ambrygen.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190130
PL  - United States
TA  - Gastroenterology
JT  - Gastroenterology
JID - 0374630
RN  - 63231-63-0 (RNA)
RN  - 9007-49-2 (DNA)
RN  - EC 3.6.1.3 (MSH2 protein, human)
RN  - EC 3.6.1.3 (MutS Homolog 2 Protein)
SB  - AIM
SB  - IM
MH  - Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
MH  - DNA/*analysis
MH  - Exons
MH  - *Gene Duplication
MH  - Genetic Testing/*methods
MH  - Humans
MH  - MutS Homolog 2 Protein/*genetics
MH  - RNA/*analysis
OTO - NOTNLM
OT  - *HNPCC
OT  - *Lynch Syndrome
OT  - *MSH2
OT  - *RNA-Seq
OT  - *Tandem Duplication
EDAT- 2019/02/03 06:00
MHDA- 2019/05/14 06:00
CRDT- 2019/02/03 06:00
PHST- 2018/07/16 00:00 [received]
PHST- 2019/01/04 00:00 [revised]
PHST- 2019/01/20 00:00 [accepted]
PHST- 2019/02/03 06:00 [pubmed]
PHST- 2019/05/14 06:00 [medline]
PHST- 2019/02/03 06:00 [entrez]
AID - S0016-5085(19)30343-9 [pii]
AID - 10.1053/j.gastro.2019.01.248 [doi]
PST - ppublish
SO  - Gastroenterology. 2019 May;156(6):1924-1925.e4. doi:
      10.1053/j.gastro.2019.01.248. Epub 2019 Jan 30.