PMID- 30666406
OWN - NLM
STAT- In-Process
LR  - 20190417
IS  - 1432-1262 (Electronic)
IS  - 0179-1958 (Linking)
VI  - 34
IP  - 4
DP  - 2019 Apr
TI  - Preoperative T staging of colon cancer using CT colonography with multiplanar
      reconstruction: new diagnostic criteria based on "bordering vessels".
PG  - 641-648
LID - 10.1007/s00384-019-03236-y [doi]
AB  - PURPOSE: Preoperative T staging of colon cancer, in particular, for
      distinguishing T3 from T2 and T4, has been a challenge. The aim of this study was
      to evaluate newly developed criteria for preoperative T staging of colorectal
      cancer using computed tomography colonography (CTC) with multiplanar
      reconstruction (MPR), based on the spatial relationship of tumors and "bordering 
      vessels," that is, marginal vessels that are detectable by multi-detector row CT 
      with MPR. METHODS: A total of 172 patients with colon and upper rectal cancer who
      underwent preoperative CTC and surgery between August 2011 and September 2013
      were included. Preoperative T staging using the new criteria was performed
      prospectively and compared with pathologic results. RESULTS: Sensitivity,
      specificity, and accuracy of T staging by CTC using the new criteria were 63%,
      80%, and 77% for T2 (n = 30); 72%, 94%, and 81% for T3 (n = 95); and 79%, 99%,
      and 97% for T4a (n = 14), respectively. Positive predictive value for T3 was 93%,
      indicating that a T3 diagnosis by CTC is precise. In addition, negative
      predictive value for pathological T4a was 98%, indicating that a "not T4a"
      diagnosis by CTC is also precise. CONCLUSIONS: Our newly developed criteria are
      useful for preoperative T staging, particularly for distinguishing T3 from T2 and
      T4.
FAU - Komono, Akira
AU  - Komono A
AD  - Colorectal Surgery Division, National Cancer Center Hospital, 5-1-1 Tsukiji,
      Chuo-ku, Tokyo, 1040045, Japan.
FAU - Shida, Dai
AU  - Shida D
AUID- ORCID: http://orcid.org/0000-0003-3294-1924
AD  - Colorectal Surgery Division, National Cancer Center Hospital, 5-1-1 Tsukiji,
      Chuo-ku, Tokyo, 1040045, Japan. dshida@ncc.go.jp.
FAU - Iinuma, Gen
AU  - Iinuma G
AD  - Department of Diagnostic Radiology, National Cancer Center Hospital, 5-1-1
      Tsukiji, Chuo-ku, Tokyo, 1040045, Japan.
FAU - Tsukamoto, Shunsuke
AU  - Tsukamoto S
AD  - Colorectal Surgery Division, National Cancer Center Hospital, 5-1-1 Tsukiji,
      Chuo-ku, Tokyo, 1040045, Japan.
FAU - Sakamoto, Ryohei
AU  - Sakamoto R
AD  - Colorectal Surgery Division, National Cancer Center Hospital, 5-1-1 Tsukiji,
      Chuo-ku, Tokyo, 1040045, Japan.
FAU - Moritani, Konosuke
AU  - Moritani K
AD  - Colorectal Surgery Division, National Cancer Center Hospital, 5-1-1 Tsukiji,
      Chuo-ku, Tokyo, 1040045, Japan.
FAU - Miyake, Mototaka
AU  - Miyake M
AD  - Department of Diagnostic Radiology, National Cancer Center Hospital, 5-1-1
      Tsukiji, Chuo-ku, Tokyo, 1040045, Japan.
FAU - Kanemitsu, Yukihide
AU  - Kanemitsu Y
AD  - Colorectal Surgery Division, National Cancer Center Hospital, 5-1-1 Tsukiji,
      Chuo-ku, Tokyo, 1040045, Japan.
LA  - eng
PT  - Journal Article
DEP - 20190121
PL  - Germany
TA  - Int J Colorectal Dis
JT  - International journal of colorectal disease
JID - 8607899
OTO - NOTNLM
OT  - CT colonography
OT  - Colon cancer
OT  - Multiplanar reconstruction (MPR)
OT  - Preoperative T staging
EDAT- 2019/01/23 06:00
MHDA- 2019/01/23 06:00
CRDT- 2019/01/23 06:00
PHST- 2019/01/04 00:00 [accepted]
PHST- 2019/01/23 06:00 [pubmed]
PHST- 2019/01/23 06:00 [medline]
PHST- 2019/01/23 06:00 [entrez]
AID - 10.1007/s00384-019-03236-y [doi]
AID - 10.1007/s00384-019-03236-y [pii]
PST - ppublish
SO  - Int J Colorectal Dis. 2019 Apr;34(4):641-648. doi: 10.1007/s00384-019-03236-y.
      Epub 2019 Jan 21.