PMID- 30317864
OWN - NLM
STAT- Publisher
LR  - 20181015
IS  - 1940-1574 (Electronic)
IS  - 0003-3197 (Linking)
DP  - 2018 Oct 15
TI  - Contrast-Induced Nephropathy and Long-Term Mortality After Percutaneous Coronary 
      Intervention in Patients With Acute Myocardial Infarction.
PG  - 3319718803677
LID - 10.1177/0003319718803677 [doi]
AB  - Abnormal hemodynamics is thought to contribute to the increased risk of
      contrast-induced nephropathy (CIN) and mortality. However, few studies focused on
      patients without abnormal hemodynamics (defined as hypotension, intra-aortic
      balloon pump usage) and reduced left ventricular ejection fraction (LVEF < 40%). 
      Our study was to explore the impact of CIN on mortality in patients with acute
      myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI)
      with relative stable hemodynamics. In this observational study, we included 696
      patients with AMI undergoing PCI without reduced LVEF and abnormal hemodynamics. 
      The end point was long-term, all-cause mortality. During the mean follow-up of
      2.79 years, CIN was detected in 110 (15.8%) patients. The total all-cause
      mortality was higher in CIN group than that in non-CIN group (24% vs 3.4%, P <
      .001). In the multivariate Cox analysis, CIN was an independent predictor of
      worse outcomes (adjusted hazard ratio [HR]: 2.97, 95% confidence interval:
      1.46-6.06, P < .001) and significantly associated with long-term mortality, so
      did renal insufficiency (adjusted HR: 4.40, P < .001) and use of beta-blockers
      (adjusted HR: 0.33, P < .001). Among patients with AMI, CIN independently
      predicted long-term mortality following PCI, regardless of LVEF impairment and
      abnormal hemodynamics.
FAU - Sun, Guoli
AU  - Sun G
AUID- ORCID: http://orcid.org/0000-0001-8888-379X
AD  - 1 Guangdong General Hospital, School of Medicine, South China University of
      Technology, Guangzhou, China.
AD  - 2 Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong
      Provincial Key Laboratory of Coronary Disease, Guangdong General Hospital,
      Guangdong Academy of Medical Sciences, Guangzhou, China.
FAU - Chen, Pengyuan
AU  - Chen P
AD  - 2 Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong
      Provincial Key Laboratory of Coronary Disease, Guangdong General Hospital,
      Guangdong Academy of Medical Sciences, Guangzhou, China.
FAU - Wang, Kun
AU  - Wang K
AD  - 2 Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong
      Provincial Key Laboratory of Coronary Disease, Guangdong General Hospital,
      Guangdong Academy of Medical Sciences, Guangzhou, China.
FAU - Li, Hualong
AU  - Li H
AD  - 2 Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong
      Provincial Key Laboratory of Coronary Disease, Guangdong General Hospital,
      Guangdong Academy of Medical Sciences, Guangzhou, China.
FAU - Chen, Shiqun
AU  - Chen S
AD  - 2 Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong
      Provincial Key Laboratory of Coronary Disease, Guangdong General Hospital,
      Guangdong Academy of Medical Sciences, Guangzhou, China.
FAU - Liu, Jin
AU  - Liu J
AD  - 2 Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong
      Provincial Key Laboratory of Coronary Disease, Guangdong General Hospital,
      Guangdong Academy of Medical Sciences, Guangzhou, China.
FAU - He, Yibo
AU  - He Y
AD  - 2 Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong
      Provincial Key Laboratory of Coronary Disease, Guangdong General Hospital,
      Guangdong Academy of Medical Sciences, Guangzhou, China.
FAU - Song, Feier
AU  - Song F
AD  - 2 Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong
      Provincial Key Laboratory of Coronary Disease, Guangdong General Hospital,
      Guangdong Academy of Medical Sciences, Guangzhou, China.
FAU - Liu, Yong
AU  - Liu Y
AD  - 1 Guangdong General Hospital, School of Medicine, South China University of
      Technology, Guangzhou, China.
AD  - 2 Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong
      Provincial Key Laboratory of Coronary Disease, Guangdong General Hospital,
      Guangdong Academy of Medical Sciences, Guangzhou, China.
FAU - Chen, Ji-Yan
AU  - Chen JY
AD  - 1 Guangdong General Hospital, School of Medicine, South China University of
      Technology, Guangzhou, China.
AD  - 2 Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong
      Provincial Key Laboratory of Coronary Disease, Guangdong General Hospital,
      Guangdong Academy of Medical Sciences, Guangzhou, China.
LA  - eng
PT  - Journal Article
DEP - 20181015
PL  - United States
TA  - Angiology
JT  - Angiology
JID - 0203706
OTO - NOTNLM
OT  - acute myocardial infarction
OT  - contrast-induced nephropathy
OT  - long-term mortality
OT  - relative stable hemodynamics
EDAT- 2018/10/16 06:00
MHDA- 2018/10/16 06:00
CRDT- 2018/10/16 06:00
PHST- 2018/10/16 06:00 [entrez]
PHST- 2018/10/16 06:00 [pubmed]
PHST- 2018/10/16 06:00 [medline]
AID - 10.1177/0003319718803677 [doi]
PST - aheadofprint
SO  - Angiology. 2018 Oct 15:3319718803677. doi: 10.1177/0003319718803677.