PMID- 30273709
OWN - NLM
STAT- Publisher
LR  - 20181001
IS  - 1097-6825 (Electronic)
IS  - 0091-6749 (Linking)
DP  - 2018 Sep 28
TI  - ARIA Phase 4 (2018): Change management in allergic rhinitis and asthma
      multimorbidity using mobile technology.
LID - S0091-6749(18)31359-9 [pii]
LID - 10.1016/j.jaci.2018.08.049 [doi]
AB  - Allergic Rhinitis and its Impact on Asthma (ARIA) has evolved from a guideline
      using the best approach to integrated care pathways (ICPs) using mobile
      technology in AR and asthma multimorbidity. The proposed next phase of ARIA is
      Change Management (CM) with the aim of providing an active and healthy life to
      rhinitis sufferers and to those with asthma multimorbidity across the life cycle 
      whatever their gender or socio-economic status in order to reduce health and
      social inequities incurred by the disease. ARIA has followed the 8-step model of 
      Kotter to assess and implement the impact of rhinitis on asthma multimorbidity
      and to propose multimorbid guidelines. A second change management strategy is
      proposed by ARIA Phase 4 to increase self-medication and shared decision making
      in rhinitis and asthma multimorbidity. An innovation of ARIA has been the
      development and validation of IT evidence-based tools (MASK: Mobile Airways
      Sentinel Network) that can inform patient decisions on the basis of a self-care
      plan proposed by the health care professional.
CI  - Copyright (c) 2018. Published by Elsevier Inc.
FAU - Bousquet, Jean
AU  - Bousquet J
AD  - University Hospital, Montpellier, France; MACVIA-France, Fondation partenariale
      FMC VIA-LR, Montpellier, France; VIMA. INSERM U 1168, VIMA : Ageing and chronic
      diseases Epidemiological and public health approaches, Villejuif, Universite
      Versailles St-Quentin-en-Yvelines, UMR-S 1168, Montigny le Bretonneux, France and
      Euforea, Brussels, Belgium. Electronic address: jean.bousquet@orange.fr.
FAU - Hellings, Peter W
AU  - Hellings PW
AD  - Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU 
      Leuven, Leuven, Belgium.
FAU - Agache, Ioana
AU  - Agache I
AD  - Transylvania University Brasov, Brasov, Romania.
FAU - Amat, Flore
AU  - Amat F
AD  - Allergology department, Centre de l'Asthme et des Allergies Hopital d'Enfants
      Armand-Trousseau (APHP); Sorbonne Universite, UPMC Univ Paris 06, UMR_S 1136,
      Institut Pierre Louis d'Epidemiologie et de Sante Publique, Equipe EPAR, Paris,
      France.
FAU - Annesi-Maesano, Isabella
AU  - Annesi-Maesano I
AD  - Epidemiology of Allergic and Respiratory Diseases, Department Institute Pierre
      Louis of Epidemiology and Public Health, INSERM and UPMC Sorbonne Universite,
      Medical School Saint Antoine, Paris, France.
FAU - Ansotegui, Ignacio J
AU  - Ansotegui IJ
AD  - Department of Allergy and Immunology, Hospital Quiron Bizkaia, Erandio, Spain.
FAU - Anto, Josep M
AU  - Anto JM
AD  - ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona,
      Spain; IMIM (Hospital del Mar Research Institute), Barcelona, Spain; CIBER
      Epidemiologia y Salud Publica (CIBERESP), Barcelona, Spain; Universitat Pompeu
      Fabra (UPF), Barcelona, Spain.
FAU - Bachert, Claus
AU  - Bachert C
AD  - Upper Airways Research Laboratory, ENT Dept, Ghent University Hospital, Ghent,
      Belgium.
FAU - Bateman, Eric D
AU  - Bateman ED
AD  - Department of Medicine, University of Cape Town, Cape Town, South Africa.
FAU - Bedbrook, Anna
AU  - Bedbrook A
AD  - MACVIA-France, Fondation partenariale FMC VIA-LR, Montpellier, France.
FAU - Bennoor, Kazi
AU  - Bennoor K
AD  - Dept of Respiratory Medicine, National Institute of Diseases of the Chest and
      Hospital, Dhaka, Bangladesh.
FAU - Bewick, Mickael
AU  - Bewick M
AD  - iQ4U Consultants Ltd, London, UK.
FAU - Bindslev-Jensen, Carsten
AU  - Bindslev-Jensen C
AD  - Department of Dermatology and Allergy Centre, Odense University Hospital, Odense 
      Research Center for Anaphylaxis (ORCA), Odense, Denmark.
FAU - Bosnic-Anticevich, Sinthia
AU  - Bosnic-Anticevich S
AD  - Woolcock Institute of Medical Research, University of Sydney and Woolcock
      Emphysema Centre and Local Health District, Glebe, NSW, Australia.
FAU - Bosse, Isabelle
AU  - Bosse I
AD  - Allergist, La Rochelle, France.
FAU - Brozek, Jan
AU  - Brozek J
AD  - Department of Health Research Methods, Evidence, and Impact, Division of
      Immunology and Allergy, Department of Medicine, McMaster University, Hamilton,
      ON, Canada.
FAU - Brussino, Luisa
AU  - Brussino L
AD  - Department of Medical Sciences, Allergy and Clinical Immunology Unit, University 
      of Torino & Mauriziano Hospital, Torino, Italy.
FAU - Canonica, Giorgio W
AU  - Canonica GW
AD  - Personalized Medicine Clinic Asthma & Allergy, Humanitas University, Humanitas
      Research Hospital, Rozzano, Milan, Italy.
FAU - Cardona, Victoria
AU  - Cardona V
AD  - Allergy Section, Department of Internal Medicine, Hospital Vall d'Hebron,
      Barcelona, Spain and ARADyAL Spanish Research Network, Barcelona, Spain.
FAU - Casale, Thomas
AU  - Casale T
AD  - Division of Allergy/Immunology, University of South Florida, Tampa, Fla.
FAU - Cepeda Sarabia, Alfonso M
AU  - Cepeda Sarabia AM
AD  - Allergy and Immunology Laboratory, Metropolitan University, Simon Bolivar
      University, Barranquilla, Colombia and SLaai, Sociedad Latinoamericana de
      Allergia, Asma e Immunologia, Branquilla, Columbia.
FAU - Chavannes, Niels H
AU  - Chavannes NH
AD  - Department of Public Health and Primary Care, Leiden University Medical Center,
      Leiden, The Netherlands.
FAU - Cecchi, Lorenzo
AU  - Cecchi L
AD  - SOS Allergology and Clinical Immunology, USL Toscana Centro, Prato, Italy.
FAU - Correia de Sousa, Jaime
AU  - Correia de Sousa J
AD  - Life and Health Sciences Research Institute (ICVS), School of Medicine,
      University of Minho, Braga, Portugal; ICVS/3B's, PT Government Associate
      Laboratory, Braga/Guimaraes, Portugal.
FAU - Costa, Elisio
AU  - Costa E
AD  - UCIBIO, REQUINTE, Faculty of Pharmacy and Competence Center on Active and Healthy
      Ageing of University of Porto (Porto4Ageing), Porto, Portugal.
FAU - Cruz, Alvaro A
AU  - Cruz AA
AD  - ProAR - Nucleo de Excelencia em Asma, Federal University of Bahia, Brasil and WHO
      GARD Planning Group, Brazil.
FAU - Czarlewski, Wienczyslawa
AU  - Czarlewski W
AD  - Medical Consulting Czarlewski, Levallois, France.
FAU - De Carlo, Giuseppe
AU  - De Carlo G
AD  - EFA European Federation of Allergy and Airways Diseases Patients' Associations,
      Brussels, Belgium.
FAU - De Feo, Giulia
AU  - De Feo G
AD  - Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana",
      University of Salerno, Salerno, Italy.
FAU - Demoly, Pascal
AU  - Demoly P
AD  - Epidemiology of Allergic and Respiratory Diseases, Department Institute Pierre
      Louis of Epidemiology and Public Health, INSERM and UPMC Sorbonne Universite,
      Medical School Saint Antoine, Paris, France; Department of Respiratory Diseases, 
      Montpellier University Hospital, France.
FAU - Devillier, Philippe
AU  - Devillier P
AD  - Laboratoire de Pharmacologie Respiratoire UPRES EA220, Hopital Foch, Suresnes,
      Universite Versailles Saint-Quentin, Universite Paris Saclay, France.
FAU - Dykewicz, Mark S
AU  - Dykewicz MS
AD  - Section of Allergy and Immunology, Saint Louis University School of Medicine,
      Saint Louis, Missouri, USA.
FAU - El-Gamal, Yehia
AU  - El-Gamal Y
AD  - Pediatric Allergy and Immunology Unit, Children's hospital, Ain Shams University,
      Cairo, Egypt.
FAU - Eller, Esben
AU  - Eller E
AD  - Department of Dermatology and Allergy Centre, Odense University Hospital, Odense 
      Research Center for Anaphylaxis (ORCA), Odense, Denmark.
FAU - Fonseca, Joao A
AU  - Fonseca JA
AD  - CINTESIS, Center for research in health technologies and information systems,
      Faculdade de Medicina da Universidade do Porto, Porto, Portugal and MEDIDA, Lda, 
      Porto, Portugal.
FAU - Fontaine, Jean-Francois
AU  - Fontaine JF
AD  - Allergist, Reims, France.
FAU - Fokkens, Wytske J
AU  - Fokkens WJ
AD  - Department of Otorhinolaryngology, Academic Medical Centres, AMC, Amsterdam, the 
      Netherlands.
FAU - Guzman, Maria-Antonieta
AU  - Guzman MA
AD  - Immunology and Allergy Division, Clinical Hospital, University of Chile,
      Santiago, Chile.
FAU - Haahtela, Tari
AU  - Haahtela T
AD  - Skin and Allergy Hospital, Helsinki University Hospital and University of
      Helsinki, Helsinki, Finland.
FAU - Illario, Magdalena
AU  - Illario M
AD  - Division for Health Innovation, Campania Region and Federico II University and
      Hospital Naples (DISMET and R1D Unit) Naples, Italy.
FAU - Ivancevich, Juan-Carlos
AU  - Ivancevich JC
AD  - Servicio de Alergia e Immunologia, Clinica Santa Isabel, Buenos Aires, Argentina.
FAU - Just, Jocelyne
AU  - Just J
AD  - Allergology department, Centre de l'Asthme et des Allergies Hopital d'Enfants
      Armand-Trousseau (APHP); Sorbonne Universite, UPMC Univ Paris 06, UMR_S 1136,
      Institut Pierre Louis d'Epidemiologie et de Sante Publique, Equipe EPAR, Paris,
      France.
FAU - Kaidashev, Igor
AU  - Kaidashev I
AD  - Ukrainina Medical Stomatological Academy, Poltava, Ukraine.
FAU - Khaitov, Musa
AU  - Khaitov M
AD  - National Research Center, Institute of Immunology, Federal Medicobiological
      Agency, Laboratory of Molecular immunology, Moscow, Russian Federation.
FAU - Kalayci, Omer
AU  - Kalayci O
AD  - Pediatric Allergy and Asthma Unit, Hacettepe University School of Medicine,
      Ankara, Turkey.
FAU - Keil, Thomas
AU  - Keil T
AD  - Institute of Social Medicine, Epidemiology and Health Economics, Charite -
      Universitatsmedizin Berlin, Berlin, and Institute for Clinical Epidemiology and
      Biometry, University of Wuerzburg, Germany.
FAU - Klimek, Ludger
AU  - Klimek L
AD  - Center for Rhinology and Allergology, Wiesbaden, Germany.
FAU - Kowalski, Marek L
AU  - Kowalski ML
AD  - Department of Immunology and Allergy, Healthy Ageing Research Center, Medical
      University of Lodz, Poland.
FAU - Kuna, Piotr
AU  - Kuna P
AD  - Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, 
      Medical University of Lodz, Poland.
FAU - Kvedariene, Violeta
AU  - Kvedariene V
AD  - Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
FAU - Larenas-Linnemann, Desiree
AU  - Larenas-Linnemann D
AD  - Center of Excellence in Asthma and Allergy, Medica Sur Clinical Foundation and
      Hospital, Mexico City, Mexico.
FAU - Laune, Daniel
AU  - Laune D
AD  - Kyomed, Montpellier, France.
FAU - Le, Lan Tt
AU  - Le LT
AD  - University of Medicine and Pharmacy, Hochiminh City, Vietnam.
FAU - Carlsen, Kai-Hakon
AU  - Carlsen KH
AD  - Oslo University Hospital, Department of Paediatrics, Oslo, and University of
      Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.
FAU - Lourenco, Olga
AU  - Lourenco O
AD  - Faculty of Health Sciences and CICS - UBI, Health Sciences Research Centre,
      University of Beira Interior, Covilha, Portugal.
FAU - Mahboub, Bassam
AU  - Mahboub B
AD  - Department of Pulmonary Medicine, Rashid Hospital, Dubai, UAE.
FAU - Mair, Alpana
AU  - Mair A
AD  - DG for Health & Social Care, Scottish Government, Edinburgh, UK.
FAU - Menditto, Enrica
AU  - Menditto E
AD  - CIRFF, Federico II University, Naples, Italy.
FAU - Milenkovic, Branislava
AU  - Milenkovic B
AD  - Clinic for Pulmonary Diseases, Clinical Center of Serbia, Faculty of Medicine,
      University of Belgrade, Serbian Association for Asthma and COPD, Belgrade,
      Serbia.
FAU - Morais-Almeida, Mario
AU  - Morais-Almeida M
AD  - Allergy Center, CUF Descobertas Hospital, Lisbon, Portugal.
FAU - Mosges, Ralp
AU  - Mosges R
AD  - Institute of Medical Statistics, and Computational Biology, Medical Faculty,
      University of Cologne, Germany and CRI-Clinical Research International-Ltd,
      Hamburg, Germany.
FAU - Mullol, Joaquim
AU  - Mullol J
AD  - Rhinology Unit & Smell Clinic, ENT Department, Hospital Clinic; Clinical &
      Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES, University of
      Barcelona, Spain.
FAU - Murray, Ruth
AU  - Murray R
AD  - Director, Medical Communications Consultant, MedScript Ltd, Dundalk, Co Louth,
      Ireland.
FAU - Naclerio, Robert
AU  - Naclerio R
AD  - Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
FAU - Namazova-Baranova, Leyla
AU  - Namazova-Baranova L
AD  - Scientific Centre of Children's Health under the MoH, Moscow, Russia.
FAU - Novellino, Ettore
AU  - Novellino E
AD  - Director of Department of Pharmacy of University of Naples Federico II, Naples,
      Italy.
FAU - O'Hehir, Robyn E
AU  - O'Hehir RE
AD  - OHEHIR. Department of Allergy, Immunology and Respiratory Medicine, Alfred
      Hospital and Central Clinical School, Monash University, Melbourne, Victoria,
      Australia; Department of Immunology, Monash University, Melbourne, Victoria,
      Australia.
FAU - Ohta, Ken
AU  - Ohta K
AD  - National Hospital Organization, Tokyo National Hospital, Tokyo, Japan.
FAU - Okamoto, Yoshitaka
AU  - Okamoto Y
AD  - Dept of Otorhinolaryngology, Chiba University Hospital, Chiba, Japan.
FAU - Okubo, Ken
AU  - Okubo K
AD  - Dept of Otolaryngology, Nippon Medical School, Tokyo, Japan.
FAU - Onorato, Gabrielle L
AU  - Onorato GL
AD  - MACVIA-France, Fondation partenariale FMC VIA-LR, Montpellier, France.
FAU - Palkonen, Susanna
AU  - Palkonen S
AD  - EFA European Federation of Allergy and Airways Diseases Patients' Associations,
      Brussels, Belgium.
FAU - Panzner, Petr
AU  - Panzner P
AD  - Department of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles 
      University Prague, Czech Republic.
FAU - Papadopoulos, Nikos G
AU  - Papadopoulos NG
AD  - Center for Pediatrics and Child Health, Institute of Human Development, Royal
      Manchester Children's Hospital, University of Manchester, Manchester, UK and
      Allergy Department, 2nd Pediatric Clinic, Athens General Children's Hospital "P&A
      Kyriakou," University of Athens, Athens, Greece.
FAU - Park, Hae-Sim
AU  - Park HS
AD  - Department of Allergy and Clinical Immunology, Ajou University School of
      Medicine, Suwon, South Korea.
FAU - Paulino, Ema
AU  - Paulino E
AD  - Farmacias Holon, Lisbon, Portugal.
FAU - Pawankar, Ruby
AU  - Pawankar R
AD  - Department of Pediatrics, Nippon Medical School, Tokyo, Japan.
FAU - Pfaar, Oliver
AU  - Pfaar O
AD  - Center for Rhinology and Allergology, Wiesbaden, Germany; Department of
      Otorhinolaryngology, Head and Neck Surgery, Universitatsmedizin Mannheim, Medical
      Faculty Mannheim, Heidelberg University, Mannheim, Germany.
FAU - Plavec, Davor
AU  - Plavec D
AD  - Children's Hospital Srebrnjak, Zagreb, School of Medicine, University J.J.
      Strossmayer, Osijek, Croatia.
FAU - Popov, Ted A
AU  - Popov TA
AD  - University Hospital 'Sv Ivan Rilski'", Sofia, Bulgaria.
FAU - Potter, Paul
AU  - Potter P
AD  - Allergy Diagnostic and Clinical Research Unit, University of Cape Town Lung
      Institute, Cape Town, South Africa.
FAU - Prokopakis, Emmanuel P
AU  - Prokopakis EP
AD  - Department of Otorhinolaryngology University of Crete School of Medicine,
      Heraklion, Greece.
FAU - Rottem, Menachem
AU  - Rottem M
AD  - Division of Allergy Asthma and Clinical Immunology, Emek Medical Center, Afula,
      Israel.
FAU - Ryan, Dermot
AU  - Ryan D
AD  - Honorary Clinical Research Fellow, Allergy and Respiratory Research Group, The
      University of Edinburgh, Edinburgh, Past President SLAAI, FACAAI, UK.
FAU - Salimaki, Johanna
AU  - Salimaki J
AD  - Association of Finnish Pharmacies, Finland.
FAU - Samolinski, Boleslaw
AU  - Samolinski B
AD  - Department of Prevention of Envinronmental Hazards and Allergology, Medical
      University of Warsaw, Poland.
FAU - Sanchez-Borges, Mario
AU  - Sanchez-Borges M
AD  - Allergy and Clinical Immunology Department, Centro Medico-Docente la, Trinidad
      and Clinica El Avila, Caracas, Venezuela.
FAU - Schunemann, Holger J
AU  - Schunemann HJ
AD  - Department of Health Research Methods, Evidence, and Impact, Division of
      Immunology and Allergy, Department of Medicine, McMaster University, Hamilton,
      ON, Canada.
FAU - Sheikh, Aziz
AU  - Sheikh A
AD  - The Usher Institute of Population Health Sciences and Informatics, The University
      of Edinburgh, Edinburgh, UK.
FAU - Sisul, Juan-Carlos
AU  - Sisul JC
AD  - Sociedad Paraguaya de Alergia Asma e Inmunologi a, Paraguay.
FAU - Rajabian-Soderlund, Rojin
AU  - Rajabian-Soderlund R
AD  - Department of Nephrology and Endocrinology, Karolinska University Hospital,
      Stockholm, Sweden.
FAU - Sooronbaev, Talant
AU  - Sooronbaev T
AD  - Kyrgyzstan National Centre of Cardiology and Internal medicine, Euro-Asian
      respiratory Society, Bishkek, Kyrgyzstan.
FAU - Stellato, Cristiana
AU  - Stellato C
AD  - Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana",
      University of Salerno, Salerno, Italy.
FAU - To, Teresa
AU  - To T
AD  - Sidkkids hospitala and Institute of Health Policy, Management and Evaluation,
      Toronto, Canada.
FAU - Todo-Bom, Ana-Maria
AU  - Todo-Bom AM
AD  - Imunoalergologia, Centro Hospitalar Universitario de Coimbra and Faculty of
      Medicine, University of Coimbra, Portugal.
FAU - Tomazic, Peter-Valentin
AU  - Tomazic PV
AD  - Department of ENT, Medical University of Graz, Austria.
FAU - Toppila-Salmi, Sanna
AU  - Toppila-Salmi S
AD  - Skin and Allergy Hospital, Helsinki University Hospital and University of
      Helsinki, Helsinki, Finland.
FAU - Valero, Antonio
AU  - Valero A
AD  - Pneumology and Allergy Department CIBERES and Clinical & Experimental Respiratory
      Immunoallergy, IDIBAPS, University of Barcelona, Spain.
FAU - Valiulis, Arunas
AU  - Valiulis A
AD  - Vilnius University Institute of Clinical Medicine, Clinic of Children's Diseases,
      and Institute of Health Sciences, Department of Public Health, Vilnius,
      Lithuania; European Academy of Paediatrics (EAP/UEMS-SP), Brussels, Belgium.
FAU - Valovirta, Erkka
AU  - Valovirta E
AD  - Department of Lung Diseases and Clinical Immunology Allergology, University of
      Turku and Terveystalo allergy clinic, Turku, Finland.
FAU - Ventura, Maria-Teresa
AU  - Ventura MT
AD  - University of Bari Medical School, Unit of Geriatric Immunoallergology, Bari,
      Italy.
FAU - Wagenmann, Martin
AU  - Wagenmann M
AD  - Dept of Otorhinolaryngology, Universitatsklinikum Dusseldorf, Germany.
FAU - Wang, De Yun
AU  - Wang Y
AD  - Department of Otolaryngology, Yong Loo Lin School of Medicine, National
      University of Singapore, Singapore, Singapore.
FAU - Wallace, Dana
AU  - Wallace D
AD  - Nova Southeastern University, Fort Lauderdale, Florida, USA.
FAU - Waserman, Susan
AU  - Waserman S
AD  - Department of Medicine, Clinical Immunology and Allergy, McMaster University,
      Hamilton, Ontario, Canada.
FAU - Wickman, Magnus
AU  - Wickman M
AD  - Centre for Clinical Research Sormland, Uppsala University, Eskilstuna, Sweden.
FAU - Yorgancioglu, Arzu
AU  - Yorgancioglu A
AD  - Celal Bayar University Department of Pulmonology, Manisa, Turkey.
FAU - Zhang, Luo
AU  - Zhang L
AD  - Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital and 
      Beijing Institute of Otolaryngology, Beijing, China.
FAU - Zhong, Nanshan
AU  - Zhong N
AD  - State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory 
      Disease, the First Affiliated Hospital of Guangzhou Medical University,
      Guangzhou, China.
FAU - Zidarn, Mihaela
AU  - Zidarn M
AD  - University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.
FAU - Zuberbier, Torsten
AU  - Zuberbier T
AD  - Comprehensive Allergy Center Charite, Department of Dermatology and Allergy,
      Charite - Universitatsmedizin Berlin; Global Allergy and Asthma European Network 
      (GA2LEN), Berlin, Germany.
CN  - MASK study group
LA  - eng
PT  - Journal Article
DEP - 20180928
PL  - United States
TA  - J Allergy Clin Immunol
JT  - The Journal of allergy and clinical immunology
JID - 1275002
OTO - NOTNLM
OT  - ARIA
OT  - Change management
OT  - asthma
OT  - rhinitis
EDAT- 2018/10/03 06:00
MHDA- 2018/10/03 06:00
CRDT- 2018/10/02 06:00
PHST- 2018/05/18 00:00 [received]
PHST- 2018/07/13 00:00 [revised]
PHST- 2018/08/13 00:00 [accepted]
PHST- 2018/10/02 06:00 [entrez]
PHST- 2018/10/03 06:00 [pubmed]
PHST- 2018/10/03 06:00 [medline]
AID - S0091-6749(18)31359-9 [pii]
AID - 10.1016/j.jaci.2018.08.049 [doi]
PST - aheadofprint
SO  - J Allergy Clin Immunol. 2018 Sep 28. pii: S0091-6749(18)31359-9. doi:
      10.1016/j.jaci.2018.08.049.