PMID- 30126655
OWN - NLM
STAT- MEDLINE
DCOM- 20190311
LR  - 20190311
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 272
DP  - 2018 Dec 1
TI  - Initial single centre experience with the novel Rhythmia(c) high density mapping 
      system in an all comer collective of 400 electrophysiological patients.
PG  - 168-174
LID - S0167-5273(18)33013-4 [pii]
LID - 10.1016/j.ijcard.2018.07.141 [doi]
AB  - BACKGROUND: A novel, automatically annotating ultra-high density mapping system
      (Rhythmia(c), Boston Scientific) collects a high number and quality of
      electrograms (EGMs). So far, data on general use in the electrophysiological
      laboratory are sparse. METHODS: We retrospectively analyzed all our ablations
      using Rhythmia and recorded patient clinical data, procedural parameters, and
      mapping parameters including the count of EGMs, mapping time, and mapping volume.
      Where appropriate, procedural parameters were compared over time to assess a
      learning curve. RESULTS: 400 patients underwent ablation of atrial fibrillation
      (n=202), typical (n=16) or atypical atrial flutter (n=49), VT (n=48), PVC (n=35),
      accessory pathways (n=14), AVNRT (n=4), and focal atrial tachycardia (n=32).
      System use was feasible, as no procedure had to be stopped for technical reasons 
      and no ablation had to be withheld because of mapping failure, and safe, with an 
      overall complication rate of 2.25%. Initial restrictions in manoeuvrability of
      the mapping catheter were overcome rapidly, as indicated by a significant
      decrease of fluoroscopy time (20 vs. 14min, p=0.02), use of contrast agent (50
      vs. 40ml; p<0.01), and (not significant) lower procedure times (194 vs. 170min;
      p=0.12; comparing the first with the last third of patients undergoing pulmonary 
      vein isolation only procedure). Ablation of complex left atrial, focal and
      ventricular tachycardias benefited from the reliable automatic annotation of a
      high number of EGMs. CONCLUSION: The use of the Rhythmia is feasible and safe.
      Initial restrictions in manoeuvrability of the Orion mapping catheter were
      overcome rapidly. The procedures that benefit the most from ultra-high density
      mapping are complex left atrial tachycardias, focal tachycardias, and ventricular
      tachycardias.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Lackermair, Korbinian
AU  - Lackermair K
AD  - Department of Medicine I, University Hospital Munich, Ludwig Maximilians
      University, Munich, Germany. Electronic address:
      korbinian.lackermair@med.uni-muenchen.de.
FAU - Kellner, Stefanie
AU  - Kellner S
AD  - Department of Medicine I, University Hospital Munich, Ludwig Maximilians
      University, Munich, Germany.
FAU - Kellnar, Antonia
AU  - Kellnar A
AD  - Department of Medicine I, University Hospital Munich, Ludwig Maximilians
      University, Munich, Germany.
FAU - Riesinger, Lisa M
AU  - Riesinger LM
AD  - Department of Medicine I, University Hospital Munich, Ludwig Maximilians
      University, Munich, Germany.
FAU - Wakili, Reza
AU  - Wakili R
AD  - Department of Medicine I, University Hospital Munich, Ludwig Maximilians
      University, Munich, Germany; Department of Cardiology and Vascular Medicine,
      West-German Heart and Vascular Center Essen, University of Essen Medical School, 
      University Duisburg-Essen, Essen, Germany; German Cardiovascular Research Centre 
      (DZHK), partner site: Munich Heart Alliance, Munich, Germany.
FAU - Sinner, Moritz F
AU  - Sinner MF
AD  - Department of Medicine I, University Hospital Munich, Ludwig Maximilians
      University, Munich, Germany; German Cardiovascular Research Centre (DZHK),
      partner site: Munich Heart Alliance, Munich, Germany.
FAU - Rizas, Konstantinos D
AU  - Rizas KD
AD  - Department of Medicine I, University Hospital Munich, Ludwig Maximilians
      University, Munich, Germany; German Cardiovascular Research Centre (DZHK),
      partner site: Munich Heart Alliance, Munich, Germany.
FAU - Fichtner, Stephanie
AU  - Fichtner S
AD  - Department of Medicine I, University Hospital Munich, Ludwig Maximilians
      University, Munich, Germany.
FAU - Estner, Heidi L
AU  - Estner HL
AD  - Department of Medicine I, University Hospital Munich, Ludwig Maximilians
      University, Munich, Germany.
LA  - eng
PT  - Journal Article
DEP - 20180802
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Catheter Ablation/*methods
MH  - Cohort Studies
MH  - Electrophysiologic Techniques, Cardiac/*methods
MH  - Female
MH  - Heart Rate/*physiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Tachycardia, Supraventricular/*diagnosis/*physiopathology
OTO - NOTNLM
OT  - 3D mapping
OT  - Ablation
OT  - Arrhythmia
OT  - High density
OT  - Orion
OT  - Rhythmia
EDAT- 2018/08/22 06:00
MHDA- 2019/03/12 06:00
CRDT- 2018/08/22 06:00
PHST- 2018/05/08 00:00 [received]
PHST- 2018/07/10 00:00 [revised]
PHST- 2018/07/30 00:00 [accepted]
PHST- 2018/08/22 06:00 [pubmed]
PHST- 2019/03/12 06:00 [medline]
PHST- 2018/08/22 06:00 [entrez]
AID - S0167-5273(18)33013-4 [pii]
AID - 10.1016/j.ijcard.2018.07.141 [doi]
PST - ppublish
SO  - Int J Cardiol. 2018 Dec 1;272:168-174. doi: 10.1016/j.ijcard.2018.07.141. Epub
      2018 Aug 2.