PMID- 30093166
OWN - NLM
STAT- Publisher
LR  - 20180810
IS  - 1873-4588 (Electronic)
IS  - 0892-1997 (Linking)
DP  - 2018 Aug 6
TI  - Acoustic Voice Analysis and Maximum Phonation Time in Relation to Voice Handicap 
      Index Score and Larynx Disease.
LID - S0892-1997(18)30132-2 [pii]
LID - 10.1016/j.jvoice.2018.07.002 [doi]
AB  - OBJECTIVES: Patients with voice-related disorders are ideally treated by a
      multidisciplinary team. Acoustic voice analysis and patient-reported outcome
      measures are recommended parts of the clinical assessment. The present paper aims
      at further documenting the importance of acoustic voice analyses, maximum
      phonation time (MPT) and Voice Handicap Index (VHI) into clinical investigations.
      STUDY DESIGN: The participants (N=80 larynx cancer, N=32 recurrent palsy, N=23
      dysfunctional, N=75 degenerative/inflammation (N=19 various excluded)) were
      included consecutively at the outpatient laryngology clinic at Haukeland
      University Hospital. In addition, a control group of 98 healthy subjects were
      included. METHOD: Voice samples, MPT, and the VHI scores in addition to standard 
      clinical information were obtained. Acoustic analyses were performed from these
      samples determining level of jitter, shimmer and Noise-to-Harmonic ratio (NHR) as
      well as analyzing frequency of a prolonged vowel. RESULTS: Jitter, shimmer, and
      NHR scores correlated strongly (r approximately 0.8; P < 0.001) to each other. By
      Analysis of Variance analyses, we have determined significant dependence on
      diagnostic group analyzing all the obtained acoustic scores (all P < 0.001). All 
      patient groups but the dysfunctional group scored to some extent worse than the
      control group (mostly at P < 0.001). In addition, jitter scores from dysfunction 
      group were lower than recurrent palsy group (P < 0.05) and shimmer scores were
      lower among dysfunctional than the cancer group (P < 0.05). Regarding NHR the
      cancer patients scored higher than the degenerative/inflammatory group (P <
      0.05). The cancer group scored with longer MPT than the degenerative/inflammatory
      (P < 0.001) and recurrent palsy groups (P < 0.05). CONCLUSION: Among larynx
      disease patients acoustic and MPT analyses segregated with all determined
      analyses between patients and control conditions except the dysfunctional group, 
      but also to some extent between various patient groups. VHI scores correlated to 
      jitter, shimmer and NHR scores among cancer and degenerative/inflammatory disease
      patients. Acoustic analyses potentially add information useful to laryngological 
      patient studies.
CI  - Copyright (c) 2018. Published by Elsevier Inc.
FAU - Karlsen, Tom
AU  - Karlsen T
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Haukeland University
      Hospital, Bergen, Norway; Department of Clinical Medicine, Faculty of Medicine
      and Dentistry, University of Bergen, Bergen, Norway; Department of Speech and
      Language, Statped Vest, Bergen, Norway. Electronic address:
      tom.karlsen@helse-bergen.no.
FAU - Sandvik, Lorentz
AU  - Sandvik L
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Haukeland University
      Hospital, Bergen, Norway.
FAU - Heimdal, John-Helge
AU  - Heimdal JH
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Haukeland University
      Hospital, Bergen, Norway; Department of Clinical Medicine, Faculty of Medicine
      and Dentistry, University of Bergen, Bergen, Norway.
FAU - Aarstad, Hans Jorgen
AU  - Aarstad HJ
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Haukeland University
      Hospital, Bergen, Norway; Department of Clinical Medicine, Faculty of Medicine
      and Dentistry, University of Bergen, Bergen, Norway.
LA  - eng
PT  - Journal Article
DEP - 20180806
PL  - United States
TA  - J Voice
JT  - Journal of voice : official journal of the Voice Foundation
JID - 8712262
OTO - NOTNLM
OT  - Acoustic voice analysis
OT  - Maximum phonation time
OT  - Norwegian
OT  - Voice disorders
OT  - Voice handicap index
EDAT- 2018/08/11 06:00
MHDA- 2018/08/11 06:00
CRDT- 2018/08/11 06:00
PHST- 2018/03/22 00:00 [received]
PHST- 2018/06/29 00:00 [revised]
PHST- 2018/07/02 00:00 [accepted]
PHST- 2018/08/11 06:00 [entrez]
PHST- 2018/08/11 06:00 [pubmed]
PHST- 2018/08/11 06:00 [medline]
AID - S0892-1997(18)30132-2 [pii]
AID - 10.1016/j.jvoice.2018.07.002 [doi]
PST - aheadofprint
SO  - J Voice. 2018 Aug 6. pii: S0892-1997(18)30132-2. doi:
      10.1016/j.jvoice.2018.07.002.