PMID- 30092328
OWN - NLM
STAT- MEDLINE
DCOM- 20190305
LR  - 20190305
IS  - 1097-6787 (Electronic)
IS  - 0190-9622 (Linking)
VI  - 80
IP  - 2
DP  - 2019 Feb
TI  - Cutaneous malignant melanoma incidence and mortality trends in Canada: A
      comprehensive population-based study.
PG  - 448-459
LID - S0190-9622(18)32343-0 [pii]
LID - 10.1016/j.jaad.2018.07.041 [doi]
AB  - BACKGROUND: The incidence of cutaneous malignant melanoma (CMM) is on the rise in
      many parts of the world. However, there is limited knowledge on the epidemiology 
      of CMM in Canada. OBJECTIVE: To conduct a comprehensive population-based study of
      CMM in Canada. METHODS: We examined patient clinical and pathologic
      characteristics as well as the incidence and mortality trends of CMM in Canada
      using 3 independent population-based registries. RESULTS: In total, 72,565
      Canadian patients were given CMM diagnoses during 1992-2010; 47.5% were women.
      Average age at the time of diagnosis was 56.5 years for women and 60.4 years for 
      men. We report a steady increase in CMM incidence and mortality rates in both
      sexes. The overall incidence rate of CMM in Canada was 12.29 cases/100,000
      person-years. We also report important differences in the incidence and mortality
      rates between Canadian provinces and territories; the highest incidence of this
      cancer was documented in Nova Scotia and Prince Edward Island. LIMITATIONS: Data 
      on race, clinical disease stage, and Breslow depth of CMM was not available.
      CONCLUSION: This study, for the first time, defines the disease burden of CMM in 
      Canada and highlights important longitudinal, geographic, and spatial differences
      in the distribution of CMM in this country.
CI  - Copyright (c) 2018 American Academy of Dermatology, Inc. Published by Elsevier
      Inc. All rights reserved.
FAU - Ghazawi, Feras M
AU  - Ghazawi FM
AD  - Division of Dermatology, University of Ottawa, Ottawa, Canada.
FAU - Cyr, Janelle
AU  - Cyr J
AD  - Divisions of Dermatology, McGill University, Montreal, Canada.
FAU - Darwich, Rami
AU  - Darwich R
AD  - Divisions of Dermatology, McGill University, Montreal, Canada.
FAU - Le, Michelle
AU  - Le M
AD  - Divisions of Dermatology, McGill University, Montreal, Canada.
FAU - Rahme, Elham
AU  - Rahme E
AD  - Clinical Epidemiology, McGill University, Montreal, Canada.
FAU - Moreau, Linda
AU  - Moreau L
AD  - Divisions of Dermatology, McGill University, Montreal, Canada.
FAU - Netchiporouk, Elena
AU  - Netchiporouk E
AD  - Divisions of Dermatology, McGill University, Montreal, Canada.
FAU - Zubarev, Andrei
AU  - Zubarev A
AD  - Divisions of Dermatology, McGill University, Montreal, Canada.
FAU - Roshdy, Osama
AU  - Roshdy O
AD  - Divisions of Dermatology, McGill University, Montreal, Canada.
FAU - Glassman, Steven J
AU  - Glassman SJ
AD  - Division of Dermatology, University of Ottawa, Ottawa, Canada.
FAU - Sasseville, Denis
AU  - Sasseville D
AD  - Divisions of Dermatology, McGill University, Montreal, Canada. Electronic
      address: denis.sasseville@mail.mcgill.ca.
FAU - Litvinov, Ivan V
AU  - Litvinov IV
AD  - Divisions of Dermatology, McGill University, Montreal, Canada. Electronic
      address: ivan.litvinov@mcgill.ca.
LA  - eng
PT  - Journal Article
DEP - 20180806
PL  - United States
TA  - J Am Acad Dermatol
JT  - Journal of the American Academy of Dermatology
JID - 7907132
RN  - Melanoma, Cutaneous Malignant
SB  - IM
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Canada/epidemiology
MH  - Disease-Free Survival
MH  - Female
MH  - Health Surveys
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Melanoma/diagnosis/*epidemiology/therapy
MH  - Middle Aged
MH  - Neoplasm Invasiveness/pathology
MH  - Neoplasm Staging
MH  - Prognosis
MH  - *Registries
MH  - Sex Distribution
MH  - Skin Neoplasms/diagnosis/*epidemiology/therapy
MH  - Survival Analysis
OTO - NOTNLM
OT  - CMM
OT  - Canada
OT  - cutaneous malignant melanoma
OT  - epidemiology
OT  - incidence
OT  - lentigo maligna melanoma
OT  - mortality
OT  - nodular melanoma
OT  - risk factors
OT  - superficial spreading melanoma
EDAT- 2018/08/10 06:00
MHDA- 2019/03/06 06:00
CRDT- 2018/08/10 06:00
PHST- 2018/05/01 00:00 [received]
PHST- 2018/07/09 00:00 [revised]
PHST- 2018/07/14 00:00 [accepted]
PHST- 2018/08/10 06:00 [pubmed]
PHST- 2019/03/06 06:00 [medline]
PHST- 2018/08/10 06:00 [entrez]
AID - S0190-9622(18)32343-0 [pii]
AID - 10.1016/j.jaad.2018.07.041 [doi]
PST - ppublish
SO  - J Am Acad Dermatol. 2019 Feb;80(2):448-459. doi: 10.1016/j.jaad.2018.07.041. Epub
      2018 Aug 6.