PMID- 29969723
OWN - NLM
STAT- MEDLINE
DCOM- 20181105
LR  - 20181105
IS  - 1872-8227 (Electronic)
IS  - 0168-8227 (Linking)
VI  - 143
DP  - 2018 Sep
TI  - Fatigue in type 1 diabetes, prevalence, predictors and comparison with the
      background population.
PG  - 71-78
LID - S0168-8227(18)30004-4 [pii]
LID - 10.1016/j.diabres.2018.06.012 [doi]
AB  - AIM: Fatigue is scarcely studied in type 1 diabetes (T1D), and the aims were to
      investigate its prevalence compared to the background population, potential
      associations, and to validate the Fatigue Questionnaire (FQ) in type 1 diabetes. 
      METHODS: Persons with T1D were recruited from three outpatient clinics in Norway.
      Fatigue was measured using the FQ, and FQ data from the Norwegian background
      population were used for comparison. Socio-demographic and clinical variables
      were obtained by self-report, clinical investigation, medical records and
      laboratory tests. RESULTS: Of 332 eligible patients, 288 (87%) were included.
      Mean age was 44.65/44.95years (SD 13.34/13.38) for females/males, respectively.
      Total fatigue (TF) was 15.31 (SD 5.51) compared to 12.2 (SD 4.0) in the
      background population (p<0.001). HADS>/=8, current menstruation, increased
      leukocytes and sleep problems were associated with increased TF. Chronic fatigue 
      (CF) was reported in 26.4% compared to 11% in the background population
      (p<0.001). HADS>/=8, increased time since diagnosis and decreased sleep quality
      were associated with CF. The validity, internal consistency and repeatability of 
      the FQ was confirmed. CONCLUSIONS: Fatigue was more common in T1D than in the
      background population, and associated with increased anxiety, depression and
      sleep problems. The FQ demonstrated satisfactory psychometric properties.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Jensen, Oystein
AU  - Jensen O
AD  - Ostfold University College, Dept of Health and Welfare, Pb 770, 1757 Halden,
      Norway; Institute of Clinical Medicine, University of Oslo, Klaus Torgards vei 3,
      0372 Oslo, Norway. Electronic address: oystein.jensen@hiof.no.
FAU - Bernklev, Tomm
AU  - Bernklev T
AD  - Vestfold Hospital Trust, Research and Development, Halfdan Wilhelmsens alle 17,
      3116 Tonsberg, Norway; Institute of Clinical Medicine, University of Oslo, Klaus 
      Torgards vei 3, 0372 Oslo, Norway. Electronic address: tomm.bernklev@siv.no.
FAU - Gibbs, Charlotte
AU  - Gibbs C
AD  - Telemark Hospital Trust, Dept of Endocrinology, Ulefossvegen 55, 3710 Skien,
      Norway. Electronic address: charlotte.gibbs@sthf.no.
FAU - Moe, Ragnar Bekkhus
AU  - Moe RB
AD  - Ostfold Hospital Trust, Dept of Internal Medicine, Kalnesveien 300, 1714 Gralum, 
      Norway. Electronic address: ragnar.bekkhus.moe@sohf.no.
FAU - Hofso, Dag
AU  - Hofso D
AD  - Vestfold Hospital Trust, Morbid Obesity Centre and Section of Endocrinology,
      Halfdan Wilhelmsens alle 17, 3116 Tonsberg, Norway. Electronic address:
      dag.hofso@siv.no.
FAU - Jelsness-Jorgensen, Lars-Petter
AU  - Jelsness-Jorgensen LP
AD  - Ostfold University College, Dept of Health and Welfare, Pb 770, 1757 Halden,
      Norway; Ostfold Hospital Trust, Dept of Internal Medicine, Kalnesveien 300, 1714 
      Gralum, Norway. Electronic address: lars.p.jelsness-jorgensen@hiof.no.
LA  - eng
PT  - Journal Article
DEP - 20180630
PL  - Ireland
TA  - Diabetes Res Clin Pract
JT  - Diabetes research and clinical practice
JID - 8508335
SB  - IM
MH  - Adult
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 1/*complications/pathology
MH  - Fatigue/epidemiology/*etiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Prevalence
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Chronic fatigue
OT  - Fatigue
OT  - Total fatigue
OT  - Type 1 diabetes
EDAT- 2018/07/04 06:00
MHDA- 2018/11/06 06:00
CRDT- 2018/07/04 06:00
PHST- 2018/01/03 00:00 [received]
PHST- 2018/05/29 00:00 [revised]
PHST- 2018/06/13 00:00 [accepted]
PHST- 2018/07/04 06:00 [pubmed]
PHST- 2018/11/06 06:00 [medline]
PHST- 2018/07/04 06:00 [entrez]
AID - S0168-8227(18)30004-4 [pii]
AID - 10.1016/j.diabres.2018.06.012 [doi]
PST - ppublish
SO  - Diabetes Res Clin Pract. 2018 Sep;143:71-78. doi: 10.1016/j.diabres.2018.06.012. 
      Epub 2018 Jun 30.