PMID- 29800632
OWN - NLM
STAT- MEDLINE
DCOM- 20181231
LR  - 20181231
IS  - 1527-9995 (Electronic)
IS  - 0090-4295 (Linking)
VI  - 118
DP  - 2018 Aug
TI  - Characterization of Septal and Punctate Scarring in Peyronie's Disease.
PG  - 87-91
LID - S0090-4295(18)30474-6 [pii]
LID - 10.1016/j.urology.2018.05.014 [doi]
AB  - OBJECTIVE: To characterize patients with isolated septal scarring (ISS) and
      punctate scarring (PS) in Peyronie's disease (PD) and to highlight the importance
      of duplex ultrasonography in the workup of patients with PD. MATERIALS AND
      METHODS: Data from all men undergoing duplex ultrasonography at London Health
      Sciences Center for PD or erectile dysfunction over a 3-year period were
      retrospectively reviewed. RESULTS: Our cohort included 722 patients with duplex
      ultrasound. ISS were demonstrated in 217 patients (30%), and PS in 197 (27%),
      with 72 (33%) and 148 (75%), respectively, having a normal physical examination. 
      In both ISS and PS groups, more than half of patients also had associated
      erectile dysfunction. Predictive factors for ISS on multivariate analysis
      included trauma history (odds ratio [OR] 1.90, P = .04) and age (OR 1.02, P =
      .01). Patients with ISS were more likely to have dorsal curvature (OR 3.81, P
      <.01). CONCLUSION: Limited data exist in the literature regarding ISS and PS in
      PD. Our study illustrates that one-third of ISS and three-quarters of PS would
      have remained unrecognized without duplex ultrasonography, and it highlights its 
      importance in the workup and subsequent management of these patients. Further
      studies are needed to better understand and to determine the at-risk patient and 
      the associated clinical implications of ISS and PS, and to ultimately provide
      optimized and individualized management strategies.
CI  - Crown Copyright (c) 2018. Published by Elsevier Inc. All rights reserved.
FAU - Punjani, Nahid
AU  - Punjani N
AD  - Division of Urology, Department of Surgery, Western University, London, Ontario, 
      Canada.
FAU - Stern, Noah
AU  - Stern N
AD  - Division of Urology, Department of Surgery, Western University, London, Ontario, 
      Canada.
FAU - Brock, Gerald
AU  - Brock G
AD  - Division of Urology, Department of Surgery, Western University, London, Ontario, 
      Canada. Electronic address: gebrock@sympatico.ca.
LA  - eng
PT  - Journal Article
DEP - 20180522
PL  - United States
TA  - Urology
JT  - Urology
JID - 0366151
SB  - IM
MH  - Adult
MH  - Aged
MH  - Canada/epidemiology
MH  - *Cicatrix/diagnosis/etiology
MH  - *Erectile Dysfunction/diagnosis/etiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Needs Assessment
MH  - Patient Care Management/*methods
MH  - *Penile Induration/complications/diagnosis/epidemiology/physiopathology
MH  - Penis/pathology
MH  - Retrospective Studies
MH  - Ultrasonography, Doppler, Duplex/methods
EDAT- 2018/05/26 06:00
MHDA- 2019/01/01 06:00
CRDT- 2018/05/26 06:00
PHST- 2018/01/23 00:00 [received]
PHST- 2018/05/04 00:00 [revised]
PHST- 2018/05/11 00:00 [accepted]
PHST- 2018/05/26 06:00 [pubmed]
PHST- 2019/01/01 06:00 [medline]
PHST- 2018/05/26 06:00 [entrez]
AID - S0090-4295(18)30474-6 [pii]
AID - 10.1016/j.urology.2018.05.014 [doi]
PST - ppublish
SO  - Urology. 2018 Aug;118:87-91. doi: 10.1016/j.urology.2018.05.014. Epub 2018 May
      22.