PMID- 29730140
OWN - NLM
STAT- MEDLINE
DCOM- 20190204
LR  - 20190215
IS  - 1532-2939 (Electronic)
IS  - 0195-6701 (Linking)
VI  - 101
IP  - 1
DP  - 2019 Jan
TI  - Multi-centre point-prevalence survey of hospital-acquired infections in Ghana.
PG  - 60-68
LID - S0195-6701(18)30257-3 [pii]
LID - 10.1016/j.jhin.2018.04.019 [doi]
AB  - BACKGROUND: There is a paucity of data describing hospital-acquired infections
      (HAIs) in Africa. OBJECTIVE: To describe the prevalence and distribution of HAIs 
      in acute care hospitals in Ghana. METHODS: Between September and December 2016,
      point-prevalence surveys were conducted in participating hospitals using
      protocols of the European Centre for Disease Prevention and Control. Medical
      records of eligible inpatients at or before 8am on the survey date were reviewed 
      to identify HAIs present at the time of the survey. FINDINGS: Ten hospitals were 
      surveyed, representing 32.9% of all acute care beds in government hospitals. Of
      2107 inpatients surveyed, 184 HAIs were identified among 172 patients,
      corresponding to an overall prevalence of 8.2%. The prevalence values in
      hospitals ranged from 3.5% to 14.4%, with higher proportions of infections in
      secondary and tertiary care facilities. The most common HAIs were surgical site
      infections (32.6%), bloodstream infections (19.5%), urinary tract infections
      (18.5%) and respiratory tract infections (16.3%). Device-associated infections
      accounted for 7.1% of HAIs. For 12.5% of HAIs, a micro-organism was reported; the
      most commonly isolated micro-organism was Escherichia coli. Approximately 61% of 
      all patients surveyed were on antibiotics; 89.5% of patients with an HAI received
      at least one antimicrobial agent on the survey date. The strongest independent
      predictors for HAI were the presence of an invasive device before onset of
      infection and duration of hospital stay. CONCLUSION: A low HAI burden was found
      compared with findings from other low- and middle-income countries.
CI  - Copyright (c) 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.
FAU - Labi, A-K
AU  - Labi AK
AD  - Department of Microbiology, Korle-Bu Teaching Hospital, Accra, Ghana.
FAU - Obeng-Nkrumah, N
AU  - Obeng-Nkrumah N
AD  - Department of Medical Laboratory Sciences, School of Biomedical and Allied Health
      Sciences, College of Health Sciences, University of Ghana, Accra, Ghana.
      Electronic address: successfulnoahforchrist@yahoo.com.
FAU - Owusu, E
AU  - Owusu E
AD  - Department of Medical Laboratory Sciences, School of Biomedical and Allied Health
      Sciences, College of Health Sciences, University of Ghana, Accra, Ghana.
FAU - Bjerrum, S
AU  - Bjerrum S
AD  - Department of Public Health, Global Health Section, University of Copenhagen,
      Copenhagen, Denmark.
FAU - Bediako-Bowan, A
AU  - Bediako-Bowan A
AD  - Department of Surgery, School of Medicine and Dentistry, College of Health
      Sciences, University of Ghana, Accra, Ghana.
FAU - Sunkwa-Mills, G
AU  - Sunkwa-Mills G
AD  - Department of Medical Microbiology, School of Biomedical and Allied Health
      Sciences, College of Health Sciences, University of Ghana, Accra, Ghana.
FAU - Akufo, C
AU  - Akufo C
AD  - Institutional Care Division, Ghana Health Service, Accra, PMB, Ministries-Accra, 
      Ghana.
FAU - Fenny, A P
AU  - Fenny AP
AD  - Institute of Statistics, Social and Economic Research, University of Ghana,
      Accra, Ghana.
FAU - Opintan, J A
AU  - Opintan JA
AD  - Department of Medical Microbiology, School of Biomedical and Allied Health
      Sciences, College of Health Sciences, University of Ghana, Accra, Ghana.
FAU - Enweronu-Laryea, C
AU  - Enweronu-Laryea C
AD  - Department of Child Health, School of Medicine and Dentistry, College of Health
      Sciences, University of Ghana, Accra, Ghana.
FAU - Debrah, S
AU  - Debrah S
AD  - Department of Surgery, Cape Coast Teaching Hospital, Cape Coast, Ghana.
FAU - Damale, N
AU  - Damale N
AD  - Department of Obstetrics and Gynaecology, Korle-Bu Teaching Hospital, Accra,
      Ghana.
FAU - Bannerman, C
AU  - Bannerman C
AD  - Institutional Care Division, Ghana Health Service, Accra, PMB, Ministries-Accra, 
      Ghana.
FAU - Newman, M J
AU  - Newman MJ
AD  - Department of Medical Microbiology, School of Biomedical and Allied Health
      Sciences, College of Health Sciences, University of Ghana, Accra, Ghana.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20180503
PL  - England
TA  - J Hosp Infect
JT  - The Journal of hospital infection
JID - 8007166
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Child
MH  - Child, Preschool
MH  - Cross Infection/*epidemiology
MH  - Cross-Sectional Studies
MH  - Escherichia coli/isolation & purification
MH  - Female
MH  - Ghana/epidemiology
MH  - Hospitals, Public
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Middle Aged
MH  - Respiratory Tract Infections/*epidemiology
MH  - Sepsis/*epidemiology
MH  - Surgical Wound Infection/*epidemiology
MH  - Urinary Tract Infections/*epidemiology
MH  - Young Adult
OTO - NOTNLM
OT  - Ghana
OT  - Hospital-acquired infection
OT  - Prevalence
EDAT- 2018/05/08 06:00
MHDA- 2019/02/05 06:00
CRDT- 2018/05/07 06:00
PHST- 2018/02/16 00:00 [received]
PHST- 2018/04/26 00:00 [accepted]
PHST- 2018/05/08 06:00 [pubmed]
PHST- 2019/02/05 06:00 [medline]
PHST- 2018/05/07 06:00 [entrez]
AID - S0195-6701(18)30257-3 [pii]
AID - 10.1016/j.jhin.2018.04.019 [doi]
PST - ppublish
SO  - J Hosp Infect. 2019 Jan;101(1):60-68. doi: 10.1016/j.jhin.2018.04.019. Epub 2018 
      May 3.