PMID- 29675592
OWN - NLM
STAT- MEDLINE
DCOM- 20181211
LR  - 20181211
IS  - 1432-1262 (Electronic)
IS  - 0179-1958 (Linking)
VI  - 33
IP  - 8
DP  - 2018 Aug
TI  - Late assessment of quality of life in patients with rectal carcinoma: comparison 
      between sphincter preservation and definitive colostomy.
PG  - 1039-1045
LID - 10.1007/s00384-018-3044-4 [doi]
AB  - PURPOSE: Patients with cancer of the lower and middle rectum who are candidates
      for curative surgery often have negative opinions on definitive colostomy. The
      purpose of this study is to compare the quality of life (QoL) of patients who
      undergo standard treatment for rectal cancer with sphincter preservation or
      definitive colostomy. METHODS: A total of 125 patients with adenocarcinoma of the
      lower or middle rectum who underwent radical surgery with curative intent with a 
      follow-up >/= 1 year were recruited: 83 patients (group 1) were subjected to low 
      anterior resection and low colorectal or coloanal anastomosis-thus preserving
      their sphincter-and 42 (group 2) were treated with abdominoperineal resection,
      followed by terminal definitive colostomy. QoL was assessed with the EORTC
      QLQ-C30 and QLQ-CR29 questionnaires. RESULTS: Health and global quality of life
      were similar between groups; however, patients who underwent definitive colostomy
      had higher scores on the emotional (p value = 0.016) and cognitive function
      scales (p value = 0.017). Patients with sphincter preservation presented with
      more symptoms that were related to stool frequency (p value < 0.001), intestinal 
      constipation (p value = 0.005), fecal incontinence (p value = 0.001), buttock
      pain (p value = 0.023), and nausea and vomiting (p value = 0.036), whereas
      patients with permanent colostomy had higher scores for dysuria (p value =
      0.033). CONCLUSION: Although global QoL scores did not differ between groups,
      patients who underwent definitive colostomy had significantly better functional
      and symptom scale scores, reflecting greater function with fewer symptoms.
FAU - Silva, Mariane Messias Reis Lima
AU  - Silva MMRL
AD  - Department of Colorectal Tumors, AC Camargo Cancer Center, Professor Antonio
      Prudente, 211, Sao Paulo, SP, 01509-900, Brazil. mari_animo@hotmail.com.
FAU - Junior, Samuel Aguiar
AU  - Junior SA
AD  - Department of Colorectal Tumors, AC Camargo Cancer Center, Professor Antonio
      Prudente, 211, Sao Paulo, SP, 01509-900, Brazil.
FAU - de Aguiar Pastore, Juliana
AU  - de Aguiar Pastore J
AD  - Department of Colorectal Tumors, AC Camargo Cancer Center, Professor Antonio
      Prudente, 211, Sao Paulo, SP, 01509-900, Brazil.
FAU - Santos, Erica Maria Monteiro
AU  - Santos EMM
AD  - Department of Colorectal Tumors, AC Camargo Cancer Center, Professor Antonio
      Prudente, 211, Sao Paulo, SP, 01509-900, Brazil.
FAU - de Oliveira Ferreira, Fabio
AU  - de Oliveira Ferreira F
AD  - Department of Colorectal Tumors, AC Camargo Cancer Center, Professor Antonio
      Prudente, 211, Sao Paulo, SP, 01509-900, Brazil.
FAU - Spencer, Ranyell Matheus S B
AU  - Spencer RMSB
AD  - Department of Colorectal Tumors, AC Camargo Cancer Center, Professor Antonio
      Prudente, 211, Sao Paulo, SP, 01509-900, Brazil.
FAU - Calsavara, Vinicius F
AU  - Calsavara VF
AD  - Department of Colorectal Tumors, AC Camargo Cancer Center, Professor Antonio
      Prudente, 211, Sao Paulo, SP, 01509-900, Brazil.
FAU - Nakagawa, Wilson Toshihiko
AU  - Nakagawa WT
AD  - Department of Colorectal Tumors, AC Camargo Cancer Center, Professor Antonio
      Prudente, 211, Sao Paulo, SP, 01509-900, Brazil.
FAU - Lopes, Ademar
AU  - Lopes A
AD  - Department of Colorectal Tumors, AC Camargo Cancer Center, Professor Antonio
      Prudente, 211, Sao Paulo, SP, 01509-900, Brazil.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20180419
PL  - Germany
TA  - Int J Colorectal Dis
JT  - International journal of colorectal disease
JID - 8607899
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Anal Canal
MH  - *Colostomy
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Quality of Life
MH  - Rectal Neoplasms/*surgery
PMC - PMC6060835
OTO - NOTNLM
OT  - Abdominoperineal resection
OT  - Colostomy
OT  - Low anterior resection
OT  - Quality of life
OT  - Rectal cancer
EDAT- 2018/04/21 06:00
MHDA- 2018/12/12 06:00
CRDT- 2018/04/21 06:00
PHST- 2018/04/04 00:00 [accepted]
PHST- 2018/04/21 06:00 [pubmed]
PHST- 2018/12/12 06:00 [medline]
PHST- 2018/04/21 06:00 [entrez]
AID - 10.1007/s00384-018-3044-4 [doi]
AID - 10.1007/s00384-018-3044-4 [pii]
PST - ppublish
SO  - Int J Colorectal Dis. 2018 Aug;33(8):1039-1045. doi: 10.1007/s00384-018-3044-4.
      Epub 2018 Apr 19.