PMID- 29630673
OWN - NLM
STAT- MEDLINE
DCOM- 20180725
LR  - 20181114
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 13
IP  - 4
DP  - 2018
TI  - Weather and risk of ST-elevation myocardial infarction revisited: Impact on young
      women.
PG  - e0195602
LID - 10.1371/journal.pone.0195602 [doi]
AB  - BACKGROUND: During the last decade, the incidence and mortality rates of
      ST-elevation myocardial infarction (STEMI) has been steadily increasing in young 
      women but not in men. Environmental variables that contribute to cardiovascular
      events in women remain ill-defined. METHODS AND RESULTS: A total of 2199
      consecutive patients presenting with acute ST-elevation myocardial infarction
      (STEMI, 25.8% women, mean age 62.6+/-12.4 years) were admitted at the Montreal
      Heart Institute between June 2010 and December 2014. Snow fall exceeding 2cm/day 
      was identified as a positive predictor for STEMI admission rates in the overall
      population (RR 1.28, 95% CI 1.07-1.48, p = 0.005), with a significant effect
      being seen in men (RR 1.30, 95% CI 1.06-1.53, p = 0.01) but not in women (p =
      NS). An age-specific analysis revealed a significant increase in hospital
      admission rates for STEMI in younger women </=55 years, (n = 104) during days
      with higher outside temperature (p = 0.004 vs men </=55 years) and longer
      daylight hours (p = 0.0009 vs men </=55 years). Accordingly, summer season,
      increased outside temperature and sunshine hours were identified as strong
      positive predictors for STEMI occurrence in women </=55 years (RR 1.66, 95% CI
      1.1-2.5, p = 0.012, RR 1.70, 95% CI 1.2-2.5, p = 0.007, and RR 1.67, 95% CI
      1.2-2.5, p = 0.011, respectively), while an opposite trend was observed in men
      </=55 years (RR for outside temperature 0.8, 95% CI 0.73-0.95, p = 0.01).
      CONCLUSION: The impact of environmental variables on STEMI is age- and
      sex-dependent. Higher temperature may play an important role in triggering such
      acute events in young women.
FAU - Gebhard, Catherine
AU  - Gebhard C
AUID- ORCID: 0000-0001-7240-5822
AD  - Montreal Heart Institute, Montreal, Canada.
AD  - Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.
AD  - University Heart Centre, Freiburg-Bad Krozingen, Bad Krozingen, Germany.
FAU - Gebhard, Caroline E
AU  - Gebhard CE
AD  - Montreal Heart Institute, Montreal, Canada.
AD  - Department of Anaesthesiology, University Hospital Basel, Basel, Switzerland.
FAU - Stahli, Barbara E
AU  - Stahli BE
AD  - Montreal Heart Institute, Montreal, Canada.
FAU - Maafi, Foued
AU  - Maafi F
AD  - Montreal Heart Institute, Montreal, Canada.
FAU - Bertrand, Marie-Jeanne
AU  - Bertrand MJ
AD  - Montreal Heart Institute, Montreal, Canada.
FAU - Wildi, Karin
AU  - Wildi K
AD  - Department of Anaesthesiology, University Hospital Basel, Basel, Switzerland.
FAU - Fortier, Annik
AU  - Fortier A
AD  - Montreal Health Innovations Coordinating Center, Montreal, Canada.
FAU - Galvan Onandia, Zurine
AU  - Galvan Onandia Z
AD  - Montreal Heart Institute, Montreal, Canada.
FAU - Toma, Aurel
AU  - Toma A
AD  - University Heart Centre, Freiburg-Bad Krozingen, Bad Krozingen, Germany.
FAU - Zhang, Zheng W
AU  - Zhang ZW
AD  - Montreal Heart Institute, Montreal, Canada.
FAU - Smith, David C
AU  - Smith DC
AD  - Montreal Heart Institute, Montreal, Canada.
FAU - Spagnoli, Vincent
AU  - Spagnoli V
AD  - Montreal Heart Institute, Montreal, Canada.
FAU - Ly, Hung Q
AU  - Ly HQ
AD  - Montreal Heart Institute, Montreal, Canada.
AD  - Department of Medicine, Universite de Montreal, Montreal, Canada.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180409
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Hospitalization
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Quebec/epidemiology
MH  - Retrospective Studies
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/*epidemiology/*etiology
MH  - Seasons
MH  - Sex Factors
MH  - *Weather
PMC - PMC5891074
EDAT- 2018/04/10 06:00
MHDA- 2018/07/26 06:00
CRDT- 2018/04/10 06:00
PHST- 2017/11/04 00:00 [received]
PHST- 2018/03/26 00:00 [accepted]
PHST- 2018/04/10 06:00 [entrez]
PHST- 2018/04/10 06:00 [pubmed]
PHST- 2018/07/26 06:00 [medline]
AID - 10.1371/journal.pone.0195602 [doi]
AID - PONE-D-17-39247 [pii]
PST - epublish
SO  - PLoS One. 2018 Apr 9;13(4):e0195602. doi: 10.1371/journal.pone.0195602.
      eCollection 2018.