PMID- 29501290
OWN - NLM
STAT- MEDLINE
DCOM- 20180402
LR  - 20190530
IS  - 1872-8464 (Electronic)
IS  - 0165-5876 (Linking)
VI  - 107
DP  - 2018 Apr
TI  - Population-based cross-sectional study to assess newborn hearing screening
      program in central Germany.
PG  - 110-120
LID - S0165-5876(18)30051-X [pii]
LID - 10.1016/j.ijporl.2018.01.035 [doi]
AB  - OBJECTIVES: Early diagnosis of congenital hearing loss is fundamental to minimize
      the negative consequences on the speech development. To lower the age at
      diagnosis and at intervention in hearing impaired children, not only universal
      newborn hearing screening (NHS) but also tracking is considered essential. The
      aim of the study was to evaluate the first six years after implementation of the 
      population based newborn hearing screening program in Saxony-Anhalt, one German
      Federal State. METHODS: The cross-sectional cohort study consisted of three
      cohort samples. Overall 102,301 infants born between January 2010 and December
      2015 were included. NHS protocol was developed as dual target group protocol with
      two sub-protocols. The screening technique included Transient Evoked Otoacoustic 
      Emissions (TEOAE) and Automated Auditory Brainstem Response (AABR) test. Newborns
      were assigned to the sub-protocols according to their audiological risk factors. 
      Additionally, to evaluate the quality of NHS and tracking (false-negative
      screening) we were analysing data from a cohort of hearing impaired children
      diagnosed up to the age of three years. We calculated quality indicators and
      compared them with international guidelines. RESULTS: 101,102 (98.8%) infants
      were screened. The prevalence of bilateral neonatal hearing loss was 2.32 per
      1000 newborns. The median age was two days at first screening, three month at
      diagnostic testing, and four month at intervention onset. 2.6% infants were lost 
      to follow-up. 56.3% had a final diagnosis of bilateral sensorineural hearing
      loss. The sensitivity of 0.85 (KI 95%: 0.76-0.91) and a specificity of 0.84 (KI
      95%: 0.84-0.85) was calculated for the NHS program. CONCLUSIONS: The analysis of 
      benchmarks and outcomes of NHS demonstrated that the program reaches its main
      goal to identify the hearing impaired newborns in a timely manner.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Rissmann, Anke
AU  - Rissmann A
AD  - Newborn Hearing Screening Tracking Centre, Malformation Monitoring Centre
      Saxony-Anhalt, Medical Faculty Otto-von-Guericke University Magdeburg, Leipziger 
      Strasse 44, 39120 Magdeburg, Germany. Electronic address:
      anke.rissmann@med.ovgu.de.
FAU - Koehn, Andrea
AU  - Koehn A
AD  - Newborn Hearing Screening Tracking Centre, Malformation Monitoring Centre
      Saxony-Anhalt, Medical Faculty Otto-von-Guericke University Magdeburg, Leipziger 
      Strasse 44, 39120 Magdeburg, Germany.
FAU - Loderstedt, Marja
AU  - Loderstedt M
AD  - Department of Otorhinolaryngology, University Hospital Magdeburg, Leipziger
      Strasse 44, 39120 Magdeburg, Germany.
FAU - Schwemmle, Cornelia
AU  - Schwemmle C
AD  - Department of Otorhinolaryngology, University Hospital Magdeburg, Leipziger
      Strasse 44, 39120 Magdeburg, Germany.
FAU - Goetze, Gerrit
AU  - Goetze G
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, Martin Luther
      University Halle-Wittenberg, University Medicine Halle (Saale),
      Ernst-Grube-Strasse 40, 06120 Halle (Saale), Germany.
FAU - Bartel, Sylva
AU  - Bartel S
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, Martin Luther
      University Halle-Wittenberg, University Medicine Halle (Saale),
      Ernst-Grube-Strasse 40, 06120 Halle (Saale), Germany.
FAU - Plontke, Stefan K
AU  - Plontke SK
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, Martin Luther
      University Halle-Wittenberg, University Medicine Halle (Saale),
      Ernst-Grube-Strasse 40, 06120 Halle (Saale), Germany.
FAU - Langer, Joerg
AU  - Langer J
AD  - Department of Otorhinolaryngology, AMEOS Hospital Halberstadt, Gleimstrasse 5,
      38820, Halberstadt, Germany.
FAU - Begall, Klaus
AU  - Begall K
AD  - Department of Otorhinolaryngology, AMEOS Hospital Halberstadt, Gleimstrasse 5,
      38820, Halberstadt, Germany.
FAU - Matulat, Peter
AU  - Matulat P
AD  - Department of Phoniatrics and Pedaudiology, University Hospital Munster,
      Kardinal-von-Galen-Ring 10, 48149 Munster, Germany.
FAU - Roehl, Friedrich-Wilhelm
AU  - Roehl FW
AD  - Department for Biometry and Medical Informatics, Medical Faculty
      Otto-von-Guericke University Magdeburg, Leipziger Strasse 44, 39120 Magdeburg,
      Germany.
FAU - Vorwerk, Ulrich
AU  - Vorwerk U
AD  - Department of Otorhinolaryngology, University Hospital Magdeburg, Leipziger
      Strasse 44, 39120 Magdeburg, Germany.
LA  - eng
PT  - Journal Article
DEP - 20180131
PL  - Ireland
TA  - Int J Pediatr Otorhinolaryngol
JT  - International journal of pediatric otorhinolaryngology
JID - 8003603
SB  - IM
EIN - Int J Pediatr Otorhinolaryngol. 2019 Apr;119:193. PMID: 30717978
MH  - Cohort Studies
MH  - Cross-Sectional Studies
MH  - Female
MH  - Germany
MH  - Hearing Loss/*epidemiology
MH  - Hearing Tests/*methods
MH  - Humans
MH  - Infant, Newborn
MH  - Male
MH  - Neonatal Screening/*methods
MH  - Program Evaluation
MH  - Sensitivity and Specificity
OTO - NOTNLM
OT  - *Adenoid
OT  - *Adenoidectomy
OT  - *Airway
OT  - *LMA
OT  - *Laryngeal
OT  - *Mask
EDAT- 2018/03/05 06:00
MHDA- 2018/04/03 06:00
CRDT- 2018/03/05 06:00
PHST- 2017/09/18 00:00 [received]
PHST- 2018/01/22 00:00 [revised]
PHST- 2018/01/23 00:00 [accepted]
PHST- 2018/03/05 06:00 [entrez]
PHST- 2018/03/05 06:00 [pubmed]
PHST- 2018/04/03 06:00 [medline]
AID - S0165-5876(18)30051-X [pii]
AID - 10.1016/j.ijporl.2018.01.035 [doi]
PST - ppublish
SO  - Int J Pediatr Otorhinolaryngol. 2018 Apr;107:110-120. doi:
      10.1016/j.ijporl.2018.01.035. Epub 2018 Jan 31.