PMID- 29499526
OWN - NLM
STAT- MEDLINE
DCOM- 20180911
LR  - 20180911
IS  - 1872-7654 (Electronic)
IS  - 0301-2115 (Linking)
VI  - 223
DP  - 2018 Apr
TI  - Uterine massage for preventing postpartum hemorrhage at cesarean delivery: Which 
      evidence?
PG  - 64-67
LID - S0301-2115(18)30080-0 [pii]
LID - 10.1016/j.ejogrb.2018.02.023 [doi]
AB  - BACKGROUND: Cesarean delivery could be complicated by postpartum hemorrhage
      (PPH), the first cause of maternal death. OBJECTIVES: To evaluate the efficacy of
      uterine massage in preventing postpartum hemorrhage at cesarean delivery. DATA
      SOURCES: Electronic databases from their inception until October 2017. STUDY
      ELIGIBILITY CRITERIA, PARTICIPANTS, AND INTERVENTIONS: We included all RCTs
      comparing uterine massage alone or as part of the active management of labor
      before or after delivery of the placenta, or both, with non-massage in the
      setting of cesarean delivery. DATA COLLECTION AND ANALYSIS: The primary outcome
      was PPH, defined as blood loss >1000mL. Meta-analysis was performed using the
      random effects model of DerSimonian and Laird, to produce summary treatment
      effects in terms of mean difference (MD) or relative risk (RR) with 95%
      confidence interval (CI). RESULTS: Only 3 RCTs comparing uterine massage vs no
      uterine massage were found. The quality of these 3 trials in general was very low
      with high or unclear risk of bias. All of them included only women in the setting
      of spontaneous vaginal delivery and none of them included cesarean delivery, and 
      therefore the meta-analysis was not feasible. CONCLUSIONS: There is not enough
      evidence to determine if uterine massage prevents postpartum hemorrhage at
      cesarean delivery.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Saccone, Gabriele
AU  - Saccone G
AD  - Department of Neuroscience, Reproductive Sciences and Dentistry, School of
      Medicine, University of Naples Federico II, Naples, Italy.
FAU - Caissutti, Claudia
AU  - Caissutti C
AD  - Department of Experimental Clinical and Medical Science, DISM, Clinic of
      Obstetrics and Gynecology, University of Udine, Udine, Italy.
FAU - Ciardulli, Andrea
AU  - Ciardulli A
AD  - Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology,
      Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA,
      USA.
FAU - Berghella, Vincenzo
AU  - Berghella V
AD  - Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology,
      Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA,
      USA. Electronic address: vincenzo.berghella@jefferson.edu.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
DEP - 20180223
PL  - Ireland
TA  - Eur J Obstet Gynecol Reprod Biol
JT  - European journal of obstetrics, gynecology, and reproductive biology
JID - 0375672
SB  - IM
MH  - Cesarean Section/*adverse effects
MH  - Female
MH  - Humans
MH  - *Massage
MH  - Postpartum Hemorrhage/*prevention & control
MH  - Pregnancy
MH  - Randomized Controlled Trials as Topic
OTO - NOTNLM
OT  - Bleeding
OT  - Cesarean section
OT  - Maternal death
OT  - Maternal mortality
OT  - Postpartum hemorrhage
EDAT- 2018/03/03 06:00
MHDA- 2018/09/12 06:00
CRDT- 2018/03/03 06:00
PHST- 2017/11/13 00:00 [received]
PHST- 2018/02/22 00:00 [accepted]
PHST- 2018/03/03 06:00 [pubmed]
PHST- 2018/09/12 06:00 [medline]
PHST- 2018/03/03 06:00 [entrez]
AID - S0301-2115(18)30080-0 [pii]
AID - 10.1016/j.ejogrb.2018.02.023 [doi]
PST - ppublish
SO  - Eur J Obstet Gynecol Reprod Biol. 2018 Apr;223:64-67. doi:
      10.1016/j.ejogrb.2018.02.023. Epub 2018 Feb 23.