PMID- 29326110
DCOM- 20190131
LR  - 20190131
IS  - 1468-201X (Electronic)
IS  - 1355-6037 (Linking)
VI  - 104
IP  - 14
DP  - 2018 Jul
TI  - Contemporary management and outcomes in congenitally corrected transposition of
      the great arteries.
PG  - 1148-1155
LID - 10.1136/heartjnl-2016-311032 [doi]
AB  - Congenitally corrected transposition of the great arteries (ccTGA) can occur in
      isolation, or in combination with other structural cardiac anomalies, most
      commonly ventricular septal defect, pulmonary stenosis and tricuspid valve
      disease. Clinical recognition can be challenging, so echocardiography is often
      the means by which definitive diagnosis is made. The tricuspid valve and right
      ventricle are on the systemic arterial side of the ccTGA circulation, and are
      therefore subject to progressive functional deterioration. The natural history of
      ccTGA is also greatly influenced by the nature and severity of accompanying
      lesions, some of which require surgical repair. Some management strategies leave 
      the right ventricle as the systemic arterial pump, but carry the risk of
      worsening heart failure. More complex 'double switch' repairs establish the left 
      ventricle as the systemic pump, and include an atrial baffle to redirect venous
      return in combination with either arterial switch or Rastelli operation (if a
      suitable ventricular septal defect permits). Occasionally, the anatomic
      peculiarities of ccTGA do not allow straightforward biventricular repair, and
      Fontan palliation is a reasonable option. Regardless of the approach selected,
      late cardiovascular complications are relatively common, so ongoing outpatient
      surveillance should be established in an age-appropriate facility with expertise 
      in congenital heart disease care.
CI  - (c) Article author(s) (or their employer(s) unless otherwise stated in the text
      of the article) 2018. All rights reserved. No commercial use is permitted unless 
      otherwise expressly granted.
FAU - Kutty, Shelby
AU  - Kutty S
AUID- ORCID: 0000-0001-9428-0979
AD  - Division of Cardiology, University of Nebraska College of Medicine and Children's
      Hospital and Medical Center, Omaha, Nebraska, USA.
FAU - Danford, David A
AU  - Danford DA
AD  - Division of Cardiology, University of Nebraska College of Medicine and Children's
      Hospital and Medical Center, Omaha, Nebraska, USA.
FAU - Diller, Gerhard-Paul
AU  - Diller GP
AD  - Division of Adult Congenital and Valvular Heart Disease, Department of
      Cardiovascular Medicine, University Hospital Munich, Munich, Germany.
FAU - Tutarel, Oktay
AU  - Tutarel O
AD  - Department of Paediatric Cardiology and Congenital Heart Disease, German Heart
      Centre Munich, Technical University of Munich, Muenster, Germany.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20180111
PL  - England
TA  - Heart
JT  - Heart (British Cardiac Society)
JID - 9602087
RN  - Congenitally corrected transposition of the great arteries
SB  - IM
CIN - Heart. 2018 Jul;104(14):1226. PMID: 29945948
CIN - Heart. 2018 Jul;104(14):1226-1227. PMID: 29945949
MH  - Atrioventricular Block/etiology
MH  - Cardiovascular Surgical Procedures/adverse effects
MH  - Coronary Vessel Anomalies/complications/diagnostic imaging
MH  - Echocardiography
MH  - Heart Septal Defects, Ventricular/complications/diagnostic imaging
MH  - Humans
MH  - Magnetic Resonance Imaging, Cine
MH  - Postoperative Complications
MH  - Pulmonary Valve Stenosis/complications/diagnostic imaging
MH  - Respiratory Distress Syndrome, Newborn/etiology
MH  - Tachypnea/etiology
MH  - Transposition of Great Vessels/complications/*diagnosis/*surgery
MH  - Tricuspid Valve/abnormalities/diagnostic imaging
MH  - Ventricular Outflow Obstruction/etiology
OT  - *cardiac magnetic resonance (CMR) imaging
OT  - *complex congenital heart disease
OT  - *congenital heart disease surgery
OT  - *echocardiography
OT  - *heart failure
COIS- Competing interests: None declared.
EDAT- 2018/01/13 06:00
MHDA- 2019/02/01 06:00
CRDT- 2018/01/13 06:00
PHST- 2017/06/01 00:00 [received]
PHST- 2017/12/13 00:00 [revised]
PHST- 2017/12/14 00:00 [accepted]
PHST- 2018/01/13 06:00 [pubmed]
PHST- 2019/02/01 06:00 [medline]
PHST- 2018/01/13 06:00 [entrez]
AID - heartjnl-2016-311032 [pii]
AID - 10.1136/heartjnl-2016-311032 [doi]
PST - ppublish
SO  - Heart. 2018 Jul;104(14):1148-1155. doi: 10.1136/heartjnl-2016-311032. Epub 2018
      Jan 11.