PMID- 29304393
OWN - NLM
STAT- MEDLINE
DCOM- 20180907
LR  - 20180907
IS  - 1872-7654 (Electronic)
IS  - 0301-2115 (Linking)
VI  - 221
DP  - 2018 Feb
TI  - Factors associated with insomnia in pregnancy: A prospective Cohort Study.
PG  - 70-75
LID - S0301-2115(17)30546-8 [pii]
LID - 10.1016/j.ejogrb.2017.12.007 [doi]
AB  - OBJECTIVE: To quantify insomnia and their components in a longitudinal cohort of 
      pregnant women and factors associated with insomnia. STUDY DESIGN: A prospective 
      cohort of 486 healthy singleton pregnancies assembled before the 14th gestational
      week (February 2013 to March 2016). Insomnia data were collected
      pre-gestationally, in each trimester and six months post-partum, analysing five
      different moments. Multiple logistic regression analysis was performed to
      generate adjusted Odds Ratios (aOR) with 95% confidence intervals (CI) of
      determinants of insomnia in each trimester, defined using Athens Insomnia Scale
      (AIS) as score >/=8. RESULTS: Insomnia prevalence was 6.1% (3.9-8.9)
      pre-gestational, 44.2% (39.3-49.6) in first trimester (T1), 46.3% (41.9-51.3) in 
      second (T2) and 63.7% (57.7-67.8) in third trimester (T3). Post-gestational
      insomnia was 33.2% (28.2-37.9) (p<0.001 pre-gestational vs T1, T2 vs T3 and T3 vs
      after pregnancy). There was worsening mean AIS score, from: 2.34 before pregnancy
      to 9.87 in T3 because the deterioration of nighttime sleep, in absolute terms,
      but daytime impact was higher in T1. Previous trimester insomnia was associated
      with insomnia in T2 (aOR=4.21, 95% CI 2.78-6.37) and T3 (aOR=4.43, 95% CI
      2.77-7.08). Pre-gestational insomnia was determinant of insomnia in T1 (aOR
      12.50, 95% CI 3.58-43.60) and obesity was associated with insomnia in T3
      (aOR=2.30, 95% CI 0.99-5.32). On the contrary, moderate physical activity reduced
      the odds of insomnia in T3 (aOR 0.65, 95% CI 0.40-1.03). CONCLUSIONS: Insomnia
      prevalence was high from the beginning of pregnancy, associated with
      pre-gestational insomnia. In late pregnancy, two out of three pregnant women
      suffering insomnia. Insomnia prevention should be targeted particularly to those 
      with high body mass index and pre-gestational insomnia.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Roman-Galvez, R M
AU  - Roman-Galvez RM
AD  - Unidad de Gestion Clinica Churriana de la Vega, Andalusian Health Service,
      C/Santa Lucia 1, Churriana de la Vega, 18194, Granada, Spain; Doctoral Program of
      Clinical Medicine and Public Health, University of Granada, Spain.
FAU - Amezcua-Prieto, C
AU  - Amezcua-Prieto C
AD  - Department of Preventive Medicine and Public Health, Faculty of Medicine,
      University of Granada, Avenida de la Investigacion, 11, 18071 Granada, Spain;
      CIBER de Epidemiologia y Salud Publica, CIBERESP, Spain; Instituto de
      Investigacion Biosanitaria ibs.GRANADA. Electronic address: carmezcua@ugr.es.
FAU - Salcedo-Bellido, I
AU  - Salcedo-Bellido I
AD  - Department of Preventive Medicine and Public Health, Faculty of Medicine,
      University of Granada, Avenida de la Investigacion, 11, 18071 Granada, Spain;
      CIBER de Epidemiologia y Salud Publica, CIBERESP, Spain; Instituto de
      Investigacion Biosanitaria ibs.GRANADA.
FAU - Martinez-Galiano, J M
AU  - Martinez-Galiano JM
AD  - CIBER de Epidemiologia y Salud Publica, CIBERESP, Spain; University of Jaen,
      Campus de las Lagunillas S/N. Edificio B3, despacho 413, 23071, Jaen, Spain.
FAU - Khan, K S
AU  - Khan KS
AD  - Department of Preventive Medicine and Public Health, Faculty of Medicine,
      University of Granada, Avenida de la Investigacion, 11, 18071 Granada, Spain;
      Women's Health Research Unit, Barts and the London School of Medicine and
      Dentistry, Queen Mary University of London, London, UK.
FAU - Bueno-Cavanillas, A
AU  - Bueno-Cavanillas A
AD  - Department of Preventive Medicine and Public Health, Faculty of Medicine,
      University of Granada, Avenida de la Investigacion, 11, 18071 Granada, Spain;
      CIBER de Epidemiologia y Salud Publica, CIBERESP, Spain; Instituto de
      Investigacion Biosanitaria ibs.GRANADA.
LA  - eng
PT  - Journal Article
DEP - 20171207
PL  - Ireland
TA  - Eur J Obstet Gynecol Reprod Biol
JT  - European journal of obstetrics, gynecology, and reproductive biology
JID - 0375672
SB  - IM
MH  - Adult
MH  - Body Mass Index
MH  - Female
MH  - Gestational Age
MH  - Humans
MH  - Pregnancy
MH  - Pregnancy Complications/*epidemiology/etiology
MH  - Prevalence
MH  - Prospective Studies
MH  - Risk Factors
MH  - Sleep Initiation and Maintenance Disorders/*epidemiology/etiology
OTO - NOTNLM
OT  - Insomnia
OT  - Obese
OT  - Physical activity
OT  - Pregnancy
OT  - Trimester
EDAT- 2018/01/06 06:00
MHDA- 2018/09/08 06:00
CRDT- 2018/01/06 06:00
PHST- 2017/10/12 00:00 [received]
PHST- 2017/12/06 00:00 [accepted]
PHST- 2018/01/06 06:00 [pubmed]
PHST- 2018/09/08 06:00 [medline]
PHST- 2018/01/06 06:00 [entrez]
AID - S0301-2115(17)30546-8 [pii]
AID - 10.1016/j.ejogrb.2017.12.007 [doi]
PST - ppublish
SO  - Eur J Obstet Gynecol Reprod Biol. 2018 Feb;221:70-75. doi:
      10.1016/j.ejogrb.2017.12.007. Epub 2017 Dec 7.