PMID- 29293141
OWN - NLM
STAT- MEDLINE
DCOM- 20180607
LR  - 20180607
IS  - 1536-0229 (Electronic)
IS  - 0363-9762 (Linking)
VI  - 43
IP  - 3
DP  - 2018 Mar
TI  - High 18F-FDG Avidity of Low-Grade Esthesioneuroblastoma.
PG  - e101-e102
LID - 10.1097/RLU.0000000000001962 [doi]
AB  - Esthesioneuroblastoma is a rare neuroectodermic tumor of the olfactory tract. An 
      F-FDG PET/CT was performed in a 75-year-old woman with cervical lymphadenopathy. 
      It demonstrated focal intense uptake (SUVmax, 72 g/mL) in an occult sphenoclival 
      tumor. Anatomopathological examination of the lymphadenopathy and the primary
      tumor biopsy revealed well-differentiated esthesioneuroblastoma. Explaining the
      paradox between tumor differentiation and PET findings, immunohistochemistry
      showed low Ki-67 but overexpression of GLUT-1 suggesting an activation of hypoxia
      pathways. Unlike many solid tumors, FDG avidity is not correlated with
      histological grade in esthesioneuroblastoma. The tumor biology may clarify the
      discrepancy between metabolic activity and cellular mitotic processes.
FAU - Jannin, Arnaud
AU  - Jannin A
FAU - Turpin, Anthony
AU  - Turpin A
FAU - Baillet, Clio
AU  - Baillet C
FAU - Aubert, Sebastien
AU  - Aubert S
FAU - Do Cao, Christine
AU  - Do Cao C
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Clin Nucl Med
JT  - Clinical nuclear medicine
JID - 7611109
RN  - 0Z5B2CJX4D (Fluorodeoxyglucose F18)
SB  - IM
MH  - Aged
MH  - Esthesioneuroblastoma, Olfactory/*diagnostic imaging/*pathology
MH  - Female
MH  - *Fluorodeoxyglucose F18
MH  - Humans
MH  - Nasal Cavity/diagnostic imaging
MH  - Neoplasm Grading
MH  - Nose Neoplasms/*diagnostic imaging/*pathology
MH  - Positron Emission Tomography Computed Tomography
EDAT- 2018/01/03 06:00
MHDA- 2018/06/08 06:00
CRDT- 2018/01/03 06:00
PHST- 2018/01/03 06:00 [pubmed]
PHST- 2018/06/08 06:00 [medline]
PHST- 2018/01/03 06:00 [entrez]
AID - 10.1097/RLU.0000000000001962 [doi]
PST - ppublish
SO  - Clin Nucl Med. 2018 Mar;43(3):e101-e102. doi: 10.1097/RLU.0000000000001962.