PMID- 29185869
OWN - NLM
STAT- In-Data-Review
LR  - 20190610
IS  - 1527-7755 (Electronic)
IS  - 0732-183X (Linking)
VI  - 36
IP  - 6
DP  - 2018 Feb 20
TI  - Development and Validation of a Novel Integrated Clinical-Genomic Risk Group
      Classification for Localized Prostate Cancer.
PG  - 581-590
LID - 10.1200/JCO.2017.74.2940 [doi]
AB  - Purpose It is clinically challenging to integrate genomic-classifier results that
      report a numeric risk of recurrence into treatment recommendations for localized 
      prostate cancer, which are founded in the framework of risk groups. We aimed to
      develop a novel clinical-genomic risk grouping system that can readily be
      incorporated into treatment guidelines for localized prostate cancer. Materials
      and Methods Two multicenter cohorts (n = 991) were used for training and
      validation of the clinical-genomic risk groups, and two additional cohorts (n =
      5,937) were used for reclassification analyses. Competing risks analysis was used
      to estimate the risk of distant metastasis. Time-dependent c-indices were
      constructed to compare clinicopathologic risk models with the clinical-genomic
      risk groups. Results With a median follow-up of 8 years for patients in the
      training cohort, 10-year distant metastasis rates for National Comprehensive
      Cancer Network (NCCN) low, favorable-intermediate, unfavorable-intermediate, and 
      high-risk were 7.3%, 9.2%, 38.0%, and 39.5%, respectively. In contrast, the
      three-tier clinical-genomic risk groups had 10-year distant metastasis rates of
      3.5%, 29.4%, and 54.6%, for low-, intermediate-, and high-risk, respectively,
      which were consistent in the validation cohort (0%, 25.9%, and 55.2%,
      respectively). C-indices for the clinical-genomic risk grouping system (0.84; 95%
      CI, 0.61 to 0.93) were improved over NCCN (0.73; 95% CI, 0.60 to 0.86) and Cancer
      of the Prostate Risk Assessment (0.74; 95% CI, 0.65 to 0.84), and 30% of patients
      using NCCN low/intermediate/high would be reclassified by the new three-tier
      system and 67% of patients would be reclassified from NCCN six-tier (very-low- to
      very-high-risk) by the new six-tier system. Conclusion A commercially available
      genomic classifier in combination with standard clinicopathologic variables can
      generate a simple-to-use clinical-genomic risk grouping that more accurately
      identifies patients at low, intermediate, and high risk for metastasis and can be
      easily incorporated into current guidelines to better risk-stratify patients.
FAU - Spratt, Daniel E
AU  - Spratt DE
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Zhang, Jingbin
AU  - Zhang J
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Santiago-Jimenez, Maria
AU  - Santiago-Jimenez M
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Dess, Robert T
AU  - Dess RT
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Davis, John W
AU  - Davis JW
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Den, Robert B
AU  - Den RB
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Dicker, Adam P
AU  - Dicker AP
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Kane, Christopher J
AU  - Kane CJ
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Pollack, Alan
AU  - Pollack A
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Stoyanova, Radka
AU  - Stoyanova R
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Abdollah, Firas
AU  - Abdollah F
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Ross, Ashley E
AU  - Ross AE
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Cole, Adam
AU  - Cole A
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Uchio, Edward
AU  - Uchio E
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Randall, Josh M
AU  - Randall JM
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Nguyen, Hao
AU  - Nguyen H
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Zhao, Shuang G
AU  - Zhao SG
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Mehra, Rohit
AU  - Mehra R
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Glass, Andrew G
AU  - Glass AG
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Lam, Lucia L C
AU  - Lam LLC
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Chelliserry, Jijumon
AU  - Chelliserry J
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - du Plessis, Marguerite
AU  - du Plessis M
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Choeurng, Voleak
AU  - Choeurng V
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Aranes, Maria
AU  - Aranes M
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Kolisnik, Tyler
AU  - Kolisnik T
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Margrave, Jennifer
AU  - Margrave J
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Alter, Jason
AU  - Alter J
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Jordan, Jennifer
AU  - Jordan J
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Buerki, Christine
AU  - Buerki C
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Yousefi, Kasra
AU  - Yousefi K
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Haddad, Zaid
AU  - Haddad Z
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Davicioni, Elai
AU  - Davicioni E
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Trabulsi, Edouard J
AU  - Trabulsi EJ
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Loeb, Stacy
AU  - Loeb S
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Tewari, Ashutosh
AU  - Tewari A
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Carroll, Peter R
AU  - Carroll PR
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Weinmann, Sheila
AU  - Weinmann S
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Schaeffer, Edward M
AU  - Schaeffer EM
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Klein, Eric A
AU  - Klein EA
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Karnes, R Jeffrey
AU  - Karnes RJ
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Feng, Felix Y
AU  - Feng FY
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
FAU - Nguyen, Paul L
AU  - Nguyen PL
AD  - Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra,
      University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System,
      Detroit, MI; Jingbin Zhang, Maria Santiago-Jimenez, Lucia L.C. Lam, Jijumon
      Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler
      Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki,
      Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, 
      British Columbia, Canada; John W. Davis, The University of Texas MD Anderson
      Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J.
      Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane,
      University of California San Diego, San Diego; Edward Uchio, University of
      California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao
      Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San
      Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of
      Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore,
      MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland,
      OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at
      Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University,
      Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, 
      Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital,
      Harvard Medical School, Boston, MA.
LA  - eng
GR  - P50 CA180995/CA/NCI NIH HHS/United States
GR  - U01 CA196390/CA/NCI NIH HHS/United States
PT  - Journal Article
DEP - 20171129
PL  - United States
TA  - J Clin Oncol
JT  - Journal of clinical oncology : official journal of the American Society of
      Clinical Oncology
JID - 8309333
CIN - J Urol. 2018 Sep;200(3):498-499. PMID: 30412981
CIN - Nat Rev Clin Oncol. 2018 Feb;15(2):66-67. PMID: 29255241
PMC - PMC6530900
MID - NIHMS1026296
EDAT- 2017/12/01 06:00
MHDA- 2017/12/01 06:00
CRDT- 2017/11/30 06:00
PHST- 2017/12/01 06:00 [pubmed]
PHST- 2017/12/01 06:00 [medline]
PHST- 2017/11/30 06:00 [entrez]
AID - 10.1200/JCO.2017.74.2940 [doi]
PST - ppublish
SO  - J Clin Oncol. 2018 Feb 20;36(6):581-590. doi: 10.1200/JCO.2017.74.2940. Epub 2017
      Nov 29.