PMID- 29164614
OWN - NLM
STAT- MEDLINE
DCOM- 20180730
LR  - 20181202
IS  - 1879-3479 (Electronic)
IS  - 0020-7292 (Linking)
VI  - 141
IP  - 1
DP  - 2018 Apr
TI  - Evaluating the utility of a point-of-care glucometer for the diagnosis of
      gestational diabetes.
PG  - 91-96
LID - 10.1002/ijgo.12399 [doi]
AB  - OBJECTIVE: To investigate the performance of the Roche Accuchek Active glucometer
      in diagnosing gestational diabetes mellitus (GDM) versus the gold-standard
      laboratory test. METHODS: In a prospective cohort observational study at a
      primary healthcare clinic in Johannesburg, South Africa, pregnant women,
      excluding known diabetics, were recruited between 2013 and 2016. A 75-g 2-hour
      oral glucose tolerance test (OGTT) was scheduled at 24-28 gestational weeks.
      Glucose was measured in venous blood (laboratory) and capillary blood
      (glucometer). GDM was diagnosed via FIGO criteria. Diagnostic accuracy was
      evaluated by calculating the sensitivity, specificity, and coefficient of
      variance (CV) of the glucometer test, and by Bland-Altman plots. RESULTS: Data
      from 529 women were analyzed. Of these, 141 (26.7%) and 79 (14.9%) were diagnosed
      with GDM by laboratory and glucometer measurements, respectively. The CV of the
      glucometer ranged from 15% to 17%. Bland-Altman plots showed a positive bias of
      the glucometer results at 0 hours, but a negative bias at 1 and 2 hours of the
      OGTT. The sensitivity and specificity of the glucometer for the diagnosis of GDM 
      were 27.0% and 89.4%, respectively. CONCLUSION: Use of the Roche Accuchek Active 
      glucometer for the diagnosis of GDM cannot be recommended.
CI  - (c) 2017 International Federation of Gynecology and Obstetrics.
FAU - Adam, Sumaiya
AU  - Adam S
AD  - Department of Obstetrics and Gynaecology, University of Pretoria, Pretoria, South
      Africa.
FAU - Rheeder, Paul
AU  - Rheeder P
AD  - Department of Internal Medicine, University of Pretoria, Pretoria, South Africa.
LA  - eng
PT  - Journal Article
DEP - 20171215
PL  - United States
TA  - Int J Gynaecol Obstet
JT  - International journal of gynaecology and obstetrics: the official organ of the
      International Federation of Gynaecology and Obstetrics
JID - 0210174
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Blood Glucose/*analysis
MH  - Cohort Studies
MH  - Diabetes, Gestational/*diagnosis
MH  - Female
MH  - Glucose Tolerance Test/*methods
MH  - Humans
MH  - *Point-of-Care Systems
MH  - Pregnancy
MH  - Prospective Studies
MH  - Sensitivity and Specificity
MH  - South Africa
MH  - Young Adult
OTO - NOTNLM
OT  - Accuracy
OT  - Gestational diabetes
OT  - Glucometer
OT  - Point-of-care testing
EDAT- 2017/11/23 06:00
MHDA- 2018/07/31 06:00
CRDT- 2017/11/23 06:00
PHST- 2017/06/01 00:00 [received]
PHST- 2017/09/05 00:00 [revised]
PHST- 2017/11/21 00:00 [accepted]
PHST- 2017/11/23 06:00 [pubmed]
PHST- 2018/07/31 06:00 [medline]
PHST- 2017/11/23 06:00 [entrez]
AID - 10.1002/ijgo.12399 [doi]
PST - ppublish
SO  - Int J Gynaecol Obstet. 2018 Apr;141(1):91-96. doi: 10.1002/ijgo.12399. Epub 2017 
      Dec 15.