PMID- 29141014
OWN - NLM
STAT- MEDLINE
DCOM- 20171211
LR  - 20171219
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 12
IP  - 11
DP  - 2017
TI  - Prevalence and risk factors of anal human papillomavirus infection among
      HIV-negative men who have sex with men in Urumqi city of Xinjiang Uyghur
      Autonomous Region, China.
PG  - e0187928
LID - 10.1371/journal.pone.0187928 [doi]
AB  - BACKGROUND: Infection with human papillomavirus (HPV) is the most common sexually
      transmitted infection among men who have sex with men (MSM). Study on prevalence 
      and risk factors of anal HPV infection among HIV-negative MSM in Northwestern
      China was rare. METHODS: We performed a cross-sectional study of HPV prevalence
      using anal swab specimens among HIV-negative MSM in Urumqi city of Xinjiang
      Uyghur Autonomous Region, China between April 1st and October 30th in 2016.
      Prevalence of any anal HPV infection, high-risk and low-risk HPV infection was
      estimated. Risk factors associated with any anal HPV infection was analyzed using
      univariate and multivariate logistic regression models. RESULTS: Among 538
      potential participants, 500(92.9%) were recruited in this study. The genotyping
      results of anal HPV infection were available for all. Of them, 259 (51.8%), 190
      (38.0%) and 141(28.2%) were positive for at least one of the targeted 37 HPV
      genotypes, high-risk HPV genotypes, and any low-risk HPV genotypes. The most
      prevalent anal HPV genotype was HPV 6(11.8%), followed by HPV 16(11.2%), HPV
      11(10.8%), HPV 51(7.0%) and HPV 18(5.4%).Among those infected with at least one
      of the targeted 37 anal HPV genotypes, 75(29.0%), 155(59.8%) and 191(73.7%) were 
      infected with 2-valent, quadrivalent and 9-valent HPV vaccine-covered genotypes. 
      Receptive anal intercourse in the past year was the only predictor of any anal
      HPV infection in multivariate logistic regression model. CONCLUSION: Prevalence
      of any anal HPV infection and high-risk HPV infection among HIV-negative MSM in
      Urumqi city of Xinjiang is high. The majority of genotypes detected in our study 
      were covered by quadrivalent and 9-valent HPV vaccines. Regular anal exams and
      early HPV vaccination among MSM may be considered in future HPV prevention
      programs in Xinjiang, China.
FAU - Tian, Tian
AU  - Tian T
AUID- ORCID: http://orcid.org/0000-0002-6103-1666
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Xinjiang
      Medical University, Urumqi, Xinjiang, China.
FAU - Mijiti, Peierdun
AU  - Mijiti P
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Xinjiang
      Medical University, Urumqi, Xinjiang, China.
FAU - Bingxue, Huang
AU  - Bingxue H
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Xinjiang
      Medical University, Urumqi, Xinjiang, China.
FAU - Fadong, Zhang
AU  - Fadong Z
AD  - Surgery Department of Toutunhe District General Hospital, Urumqi, Xinjiang,
      China.
FAU - Ainiwaer, Abidan
AU  - Ainiwaer A
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Xinjiang
      Medical University, Urumqi, Xinjiang, China.
FAU - Guoyao, Sang
AU  - Guoyao S
AD  - Clinical Laboratory of Xinjiang Medical University First Affiliated Hospital,
      Urumqi, Xinjiang, China.
FAU - Zhanlin, Zhang
AU  - Zhanlin Z
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Xinjiang
      Medical University, Urumqi, Xinjiang, China.
FAU - Mahan, Yeledan
AU  - Mahan Y
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Xinjiang
      Medical University, Urumqi, Xinjiang, China.
FAU - Xiaoqin, Tuo
AU  - Xiaoqin T
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Xinjiang
      Medical University, Urumqi, Xinjiang, China.
FAU - Zheng, Gong
AU  - Zheng G
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Xinjiang
      Medical University, Urumqi, Xinjiang, China.
FAU - Jianghong, Dai
AU  - Jianghong D
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Xinjiang
      Medical University, Urumqi, Xinjiang, China.
LA  - eng
PT  - Journal Article
DEP - 20171115
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Adult
MH  - Alphapapillomavirus/classification/genetics/*isolation & purification
MH  - Anus Diseases/*epidemiology/virology
MH  - China/epidemiology
MH  - Cross-Sectional Studies
MH  - Genes, Viral
MH  - *HIV Seronegativity
MH  - *Homosexuality, Male
MH  - Humans
MH  - Male
MH  - Prevalence
MH  - Regression Analysis
MH  - Risk Factors
MH  - *Sexual Partners
MH  - Tumor Virus Infections/*epidemiology/transmission/virology
PMC - PMC5687769
EDAT- 2017/11/16 06:00
MHDA- 2017/12/12 06:00
CRDT- 2017/11/16 06:00
PHST- 2017/07/19 00:00 [received]
PHST- 2017/10/27 00:00 [accepted]
PHST- 2017/11/16 06:00 [entrez]
PHST- 2017/11/16 06:00 [pubmed]
PHST- 2017/12/12 06:00 [medline]
AID - 10.1371/journal.pone.0187928 [doi]
AID - PONE-D-17-27017 [pii]
PST - epublish
SO  - PLoS One. 2017 Nov 15;12(11):e0187928. doi: 10.1371/journal.pone.0187928.
      eCollection 2017.