PMID- 29140818
OWN - NLM
STAT- MEDLINE
DCOM- 20180223
LR  - 20180223
IS  - 1531-7021 (Electronic)
IS  - 1040-8738 (Linking)
VI  - 29
IP  - 2
DP  - 2018 Mar
TI  - Drop instillation and glaucoma.
PG  - 171-177
LID - 10.1097/ICU.0000000000000451 [doi]
AB  - PURPOSE OF REVIEW: To describe the current state of knowledge regarding glaucoma 
      patients' eye drop technique, interventions attempting to improve eye drop
      technique, and methods for assessing eye drop technique. RECENT FINDINGS: In
      observational studies, between 18.2 and 80% of patients contaminate their eye
      drop bottle by touching their eye or face, 11.3-60.6% do not instill exactly one 
      drop, and 6.8-37.3% miss the eye with the drop. Factors significantly associated 
      with poorer technique include older age, lack of instruction on eye drop
      technique, female sex, arthritis, more severe visual field defect, lack of
      positive reinforcement to take eye drops, lower educational level, low
      self-efficacy, and being seen at a clinic rather than a private practice. Among
      intervention studies, four of five studies using a mechanical device and three of
      four studies using educational interventions to improve technique showed positive
      results, but none of the studies were randomized controlled trials. SUMMARY: Poor
      eye drop technique is a significant impediment to achieving good control of
      intraocular pressure in glaucoma. Both mechanical device interventions and
      educational interventions offer promise to improve patients' technique, but
      studies with stronger designs need to be done followed by introduction into
      clinical practice.
FAU - Davis, Scott A
AU  - Davis SA
AD  - Division of Pharmaceutical Outcomes and Policy, University of North Carolina
      Eshelman School of Pharmacy.
FAU - Sleath, Betsy
AU  - Sleath B
AD  - Division of Pharmaceutical Outcomes and Policy, University of North Carolina
      Eshelman School of Pharmacy.
AD  - Cecil G. Sheps Center for Health Services Research, Chapel Hill, North Carolina.
FAU - Carpenter, Delesha M
AU  - Carpenter DM
AD  - Division of Pharmaceutical Outcomes and Policy, University of North Carolina
      Eshelman School of Pharmacy.
FAU - Blalock, Susan J
AU  - Blalock SJ
AD  - Division of Pharmaceutical Outcomes and Policy, University of North Carolina
      Eshelman School of Pharmacy.
FAU - Muir, Kelly W
AU  - Muir KW
AD  - Department of Ophthalmology, Duke University School of Medicine, Durham, North
      Carolina.
FAU - Budenz, Donald L
AU  - Budenz DL
AD  - Department of Ophthalmology, University of North Carolina at Chapel Hill, Chapel 
      Hill, North Carolina, USA.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Ophthalmol
JT  - Current opinion in ophthalmology
JID - 9011108
RN  - 0 (Antihypertensive Agents)
RN  - 0 (Ophthalmic Solutions)
SB  - IM
MH  - *Administration, Ophthalmic
MH  - Antihypertensive Agents/*administration & dosage
MH  - Drug Packaging
MH  - Glaucoma/*drug therapy
MH  - Humans
MH  - Intraocular Pressure/drug effects
MH  - Medication Adherence
MH  - Ophthalmic Solutions/*administration & dosage
MH  - Patient Education as Topic
MH  - Tonometry, Ocular
EDAT- 2017/11/16 06:00
MHDA- 2018/02/24 06:00
CRDT- 2017/11/16 06:00
PHST- 2017/11/16 06:00 [pubmed]
PHST- 2018/02/24 06:00 [medline]
PHST- 2017/11/16 06:00 [entrez]
AID - 10.1097/ICU.0000000000000451 [doi]
PST - ppublish
SO  - Curr Opin Ophthalmol. 2018 Mar;29(2):171-177. doi: 10.1097/ICU.0000000000000451.