PMID- 29130649
OWN - NLM
STAT- MEDLINE
DCOM- 20190130
LR  - 20190130
IS  - 1749-4486 (Electronic)
IS  - 1749-4478 (Linking)
VI  - 43
IP  - 2
DP  - 2018 Apr
TI  - Sino-Nasal Outcome Test-22 quality-of-life patterns in patients presenting with
      nasal septal perforation.
PG  - 604-608
LID - 10.1111/coa.13031 [doi]
AB  - OBJECTIVES: To assess the impact of nasal septal perforation (NSP) on quality of 
      life. DESIGN: Retrospective cohort study. SETTING: Rhinology clinics from two
      hospitals in Liverpool, United Kingdom. PARTICIPANTS: Patients diagnosed with
      NSP. MAIN OUTCOME MEASURES: Patients (n = 26) diagnosed with NSP completed the
      Sino-Nasal Outcome Test-22 (SNOT-22). The collated data were compared with
      SNOT-22 scores from a cohort of healthy volunteers (n = 34) and a cohort of
      patients (n = 30) diagnosed with chronic rhinosinusitis (CRS). RESULTS: The mean 
      total SNOT-22 score of NSP and CRS cohorts was higher than that observed in
      healthy volunteers. The mean total SNOT-22 score in the CRS cohort (57.2,
      standard deviation SD 10.3) was the higher than NSP (50.2, SD 23.5), although
      this difference did not achieve statistical significance. The mean score for the 
      rhinologic-specific domains (rhinologic symptoms, extranasal rhinologic
      symptoms), ear/facial symptoms and psychological dysfunction domain was higher in
      the CRS cohort compared to NSP, although statistical significance was only
      observed in the extranasal rhinologic symptoms domain (11.2, SD 2.4 vs 6.4, SD
      4.1). Conversely, the mean sleep dysfunction domain score for NSP (12.7, SD 7.5) 
      was higher than CRS (10.0, SD 4.9, respectively) although this was not
      statistically significant. CONCLUSIONS: This study has assessed the clinimetric
      and psychometric properties of patients suffering from symptomatic NSP. Future
      reports should consider inclusion of SNOT-22 data but with the addition of
      perforation-specific symptoms (nasal crusting, epistaxis, whistling noise).
CI  - (c) 2017 John Wiley & Sons Ltd.
FAU - Leong, S C
AU  - Leong SC
AUID- ORCID: 0000-0002-7213-0387
AD  - Department of Otorhinolaryngology - Head and Neck Surgery, Aintree University
      Hospital NHS Foundation Trust, Liverpool, UK.
FAU - Webb, C J
AU  - Webb CJ
AD  - Department of Otorhinolaryngology - Head and Neck Surgery, Royal Liverpool and
      Broadgreen Hospitals NHS trust, Liverpool, UK.
LA  - eng
PT  - Journal Article
DEP - 20171204
PL  - England
TA  - Clin Otolaryngol
JT  - Clinical otolaryngology : official journal of ENT-UK ; official journal of
      Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
JID - 101247023
SB  - IM
MH  - Adult
MH  - Aged
MH  - Case-Control Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nasal Septal Perforation/*complications/*psychology/surgery
MH  - Outcome Assessment (Health Care)
MH  - Psychometrics
MH  - *Quality of Life
MH  - Retrospective Studies
MH  - *Symptom Assessment
MH  - United Kingdom
MH  - Young Adult
OTO - NOTNLM
OT  - *facial pain
OT  - *nasal septal perforation
OT  - *outcome assessment
OT  - *sinusitis
EDAT- 2017/11/14 06:00
MHDA- 2019/01/31 06:00
CRDT- 2017/11/14 06:00
PHST- 2017/11/02 00:00 [accepted]
PHST- 2017/11/14 06:00 [pubmed]
PHST- 2019/01/31 06:00 [medline]
PHST- 2017/11/14 06:00 [entrez]
AID - 10.1111/coa.13031 [doi]
PST - ppublish
SO  - Clin Otolaryngol. 2018 Apr;43(2):604-608. doi: 10.1111/coa.13031. Epub 2017 Dec
      4.