PMID- 29020413
OWN - NLM
STAT- In-Data-Review
LR  - 20180531
IS  - 1522-9645 (Electronic)
IS  - 0195-668X (Linking)
VI  - 39
IP  - 8
DP  - 2018 Feb 21
TI  - Incidence, predictors, and clinical outcomes of coronary obstruction following
      transcatheter aortic valve replacement for degenerative bioprosthetic surgical
      valves: insights from the VIVID registry.
PG  - 687-695
LID - 10.1093/eurheartj/ehx455 [doi]
AB  - Aims: There are limited data on coronary obstruction following transcatheter
      valve-in-valve (ViV) implantation inside failed aortic bioprostheses. The
      objectives of this study were to determine the incidence, predictors, and
      clinical outcomes of coronary obstruction in transcatheter ViV procedures.
      Methods and results: A total of 1612 aortic procedures from the Valve-in-Valve
      International Data (VIVID) Registry were evaluated. Data were subject to
      centralized blinded corelab computed tomography (CT) analysis in a subset of
      patients. The virtual transcatheter valve to coronary ostium distance (VTC) was
      determined. A total of 37 patients (2.3%) had clinically evident coronary
      obstruction. Baseline clinical characteristics in the coronary obstruction
      patients were similar to controls. Coronary obstruction was more common in
      stented bioprostheses with externally mounted leaflets or stentless bioprostheses
      than in stented with internally mounted leaflets bioprostheses (6.1% vs. 3.7% vs.
      0.8%, respectively; P < 0.001). CT measurements were obtained in 20 (54%) and 90 
      (5.4%) of patients with and without coronary obstruction, respectively. VTC
      distance was shorter in coronary obstruction patients in relation to controls
      (3.24 +/- 2.22 vs. 6.30 +/- 2.34, respectively; P < 0.001). Using multivariable
      analysis, the use of a stentless or stented bioprosthesis with externally mounted
      leaflets [odds ratio (OR): 7.67; 95% confidence interval (CI): 3.14-18.7; P <
      0.001] associated with coronary obstruction for the global population. In a
      second model with CT data, a shorter VTC distance predicted this complication
      (OR: 0.22 per 1 mm increase; 95% CI: 0.09-0.51; P < 0.001), with an optimal
      cut-off level of 4 mm (area under the curve: 0.943; P < 0.001). Coronary
      obstruction was associated with a high 30-day mortality (52.9% vs. 3.9% in the
      controls, respectively; P < 0.001). Conclusion: Coronary obstruction following
      aortic ViV procedures is a life-threatening complication that occurred more
      frequently in patients with prior stentless or stented bioprostheses with
      externally mounted leaflets and in those with a short VTC.
CI  - Published on behalf of the European Society of Cardiology. All rights reserved.
      (c) The Author 2017. For permissions, please email: journals.permissions@oup.com.
FAU - Ribeiro, Henrique B
AU  - Ribeiro HB
AD  - Department of Cardiology, Quebec Heart and Lung Institute, Laval University,
      2725, Chemin Ste Foy, G1V 4G5 Quebec City, Canada.
AD  - Department of Cardiology, Heart Institute of Sao Paulo (InCor), University of Sao
      Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, 05403-900 Sao Paulo, Brazil.
FAU - Rodes-Cabau, Josep
AU  - Rodes-Cabau J
AD  - Department of Cardiology, Quebec Heart and Lung Institute, Laval University,
      2725, Chemin Ste Foy, G1V 4G5 Quebec City, Canada.
FAU - Blanke, Philipp
AU  - Blanke P
AD  - Division of Cardiology, St. Paul's Hospital, 1081 Burrard Street, V6Z 1Y6
      Vancouver, Canada.
FAU - Leipsic, Jonathon
AU  - Leipsic J
AD  - Division of Cardiology, St. Paul's Hospital, 1081 Burrard Street, V6Z 1Y6
      Vancouver, Canada.
FAU - Kwan Park, Jong
AU  - Kwan Park J
AD  - Division of Cardiology, St. Paul's Hospital, 1081 Burrard Street, V6Z 1Y6
      Vancouver, Canada.
FAU - Bapat, Vinayak
AU  - Bapat V
AD  - Cardiac Surgery, St. Thomas Hospital, 6th Floor, East Wing Street, Westminster
      Bridge Road, SE1 7EH London, UK.
FAU - Makkar, Raj
AU  - Makkar R
AD  - Cardiac Catherization Laboratory, Cedars-Sinai Medical Center, Advanced Health
      Sciences Pavilion, A3600 127 S. San Vicente Blvd., 90048 Los Angeles, CA, USA.
FAU - Simonato, Matheus
AU  - Simonato M
AD  - Division of Cardiology, St. Paul's Hospital, 1081 Burrard Street, V6Z 1Y6
      Vancouver, Canada.
AD  - Division of Cardiac Surgery, Escola Paulista de Medicina - UNIFESP, R. Botucatu, 
      740, 04023-062 Sao Paulo, Brazil.
FAU - Barbanti, Marco
AU  - Barbanti M
AD  - Division of Interventional Cardiology, Ferrarotto Hospital, Via S. Sofia, 78,
      95123 Catania, Italy.
FAU - Schofer, Joachim
AU  - Schofer J
AD  - Cardiology Department, Albertinen Herz- und Gefasszentrum Hamburg, Hogenfelder
      Strasse, 22, 22457 Hamburg, Germany.
FAU - Bleiziffer, Sabine
AU  - Bleiziffer S
AD  - Department of Cardiovascular Surgery, German Heart Center of the State of
      Bavaria, Lazarettstrasse 36, 80636 Munich, Germany.
FAU - Latib, Azeem
AU  - Latib A
AD  - Cardiologia Interventistica ed Emodinamica, Ospedale San Raffaele, Via Olgettina,
      60 - 20132 Milan, Italy.
FAU - Hildick-Smith, David
AU  - Hildick-Smith D
AD  - Interventional Cardiology, Sussex Cardiac Centre, Eastern Road, BN2 5BE Brighton,
      UK.
FAU - Presbitero, Patrizia
AU  - Presbitero P
AD  - Cardiologia Clinica e Interventistica, Humanitas, Via Alessandro Manzoni, 56,
      20089 Milan, Italy.
FAU - Windecker, Stephan
AU  - Windecker S
AD  - Universitatsklinik fur Kardiologie, Universitatsspital Bern, Freiburgstrasse 4,
      3010 Bern, Switzerland.
FAU - Napodano, Massimo
AU  - Napodano M
AD  - Interventional Cardiology, University of Padova, Via Giustiniani, 2 - 35128
      Padova, Italy.
FAU - Cerillo, Alfredo G
AU  - Cerillo AG
AD  - Division of Cardiac Surgery, G. Pasquinucci Hospital, Via Vittorio Veneto, 293,
      55049 Massa, Italy.
FAU - Abdel-Wahab, Mohamed
AU  - Abdel-Wahab M
AD  - Innere Medizin, Kardiologie, Segeberger Kliniken, Krankenhausstrasse 2, 23795 Bad
      Segeberg, Germany.
FAU - Tchetche, Didier
AU  - Tchetche D
AD  - General Interventional Cardiology, Clinique Pasteur, 45 avenue de Lombez, BP
      27617, 31076 Toulouse, France.
FAU - Fiorina, Claudia
AU  - Fiorina C
AD  - Cardiothoracic Department, Spedali Civili Brescia, Piazzale Spedali Civili, 1,
      25123 Brescia, Italy.
FAU - Sinning, Jan-Malte
AU  - Sinning JM
AD  - Medizinische Klinik und Poliklinik II, Universitatsklinikum Bonn,
      Sigmund-Freud-Strasse, 25, 53127 Bonn, Germany.
FAU - Cohen, Mauricio G
AU  - Cohen MG
AD  - Cardiac Catheterization Lab, University of Miami Miller School of Medicine, 1400 
      NW 12th Ave, 33136 Miami, FL, USA.
FAU - Guerrero, Mayra E
AU  - Guerrero ME
AD  - Interventional Cardiology, Evanston Hospital, 2650 Ridge Avenue, 60201 Evanston, 
      IL, USA.
FAU - Whisenant, Brian
AU  - Whisenant B
AD  - Division of Cardiology, Intermountain Healthcare, 5169 S Cottonwood St Ste 520,
      84107 Murray, UT, USA.
FAU - Nietlispach, Fabian
AU  - Nietlispach F
AD  - Universitares Herzzentrum Zurich, Universitatsspital Zurich, Ramistrasse 100,
      8091 Zurich, Switzerland.
FAU - Palma, Jose Honorio
AU  - Palma JH
AD  - Department of Cardiology, Heart Institute of Sao Paulo (InCor), University of Sao
      Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, 05403-900 Sao Paulo, Brazil.
AD  - Division of Cardiac Surgery, Escola Paulista de Medicina - UNIFESP, R. Botucatu, 
      740, 04023-062 Sao Paulo, Brazil.
FAU - Nombela-Franco, Luis
AU  - Nombela-Franco L
AD  - Interventional Cardiology, Hospital Clinico San Carlos, Calle del Prof Martin
      Lagos, s/n, 28040 Madrid, Spain.
FAU - de Weger, Arend
AU  - de Weger A
AD  - Department of Cardiothoracic Surgery, Leids Universitair Medisch Centrum,
      Albinusdreef 2, Postbus 9600, 2300 Leiden, The Netherlands.
FAU - Kass, Malek
AU  - Kass M
AD  - Division of Cardiology, St. Boniface General Hospital, 409 Tache Ave, R2H 2A6
      Winnipeg, Canada.
FAU - Sandoli de Brito, Fabio Jr
AU  - Sandoli de Brito F Jr
AD  - Division of Cardiology, Hospital Israelita Albert Einstein, Av. Albert Einstein, 
      627, 05652-900 Sao Paulo, Brazil.
FAU - Lemos, Pedro A
AU  - Lemos PA
AD  - Department of Cardiology, Heart Institute of Sao Paulo (InCor), University of Sao
      Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, 05403-900 Sao Paulo, Brazil.
AD  - Division of Cardiology, Hospital Israelita Albert Einstein, Av. Albert Einstein, 
      627, 05652-900 Sao Paulo, Brazil.
FAU - Kornowski, Ran
AU  - Kornowski R
AD  - Division of Interventional Cardiology, Rabin Medical Center, Ze'ev Jabotinsky Rd 
      39, 4941492 Petah Tikva, Israel.
FAU - Webb, John
AU  - Webb J
AD  - Division of Cardiology, St. Paul's Hospital, 1081 Burrard Street, V6Z 1Y6
      Vancouver, Canada.
FAU - Dvir, Danny
AU  - Dvir D
AD  - Division of Cardiology, St. Paul's Hospital, 1081 Burrard Street, V6Z 1Y6
      Vancouver, Canada.
AD  - Division of Cardiology, University of Washington, 1959 NE Pacific St, 98195
      Seattle, WA, USA.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Eur Heart J
JT  - European heart journal
JID - 8006263
EDAT- 2017/10/12 06:00
MHDA- 2017/10/12 06:00
CRDT- 2017/10/12 06:00
PHST- 2017/01/02 00:00 [received]
PHST- 2017/07/19 00:00 [accepted]
PHST- 2017/10/12 06:00 [pubmed]
PHST- 2017/10/12 06:00 [medline]
PHST- 2017/10/12 06:00 [entrez]
AID - 4082639 [pii]
AID - 10.1093/eurheartj/ehx455 [doi]
PST - ppublish
SO  - Eur Heart J. 2018 Feb 21;39(8):687-695. doi: 10.1093/eurheartj/ehx455.