PMID- 28914687
OWN - NLM
STAT- MEDLINE
DCOM- 20171226
LR  - 20171226
IS  - 1531-7021 (Electronic)
IS  - 1040-8738 (Linking)
VI  - 29
IP  - 1
DP  - 2018 Jan
TI  - Prevention of macular edema after cataract surgery.
PG  - 48-53
LID - 10.1097/ICU.0000000000000436 [doi]
AB  - PURPOSE OF REVIEW: Although cataract surgery can effectively restore visual
      function in many patients with cataract, PCME remains an important cause of
      suboptimal visual acuity. The present review provides an overview of the current 
      literature on the prevention and treatment of PCME. RECENT FINDINGS: Optimal
      prevention of PCME starts preoperatively with a personalized risk assessment.
      Diabetes mellitus, retinal vein occlusion, epiretinal membrane, macular hole, and
      uveitis are the most important risk factors for developing cystoid macular edema 
      after cataract surgery. Topical NSAIDs either in addition to, or instead of,
      topical corticosteroids reduce the risk of developing PCME. Additional
      intravitreal corticosteroid and antivascular endothelial growth factor injections
      have been studied in patients with diabetes. Timely diagnosis and treatment of
      PCME is essential. Topical NSAIDs solely, or in addition to corticosteroids,
      improve visual acuity in patients with PCME. Oral acetazolamide and intravitreal 
      dexamethasone implants have been used in refractory cases. SUMMARY: Topical
      NSAIDs can be used solely, or in combination with topical corticosteroids, to
      prevent and treat PCME. Further research is needed to compare the efficacy of
      various NSAIDs, and to investigate the cost-effectiveness and long-term benefit
      of anti-inflammatory treatments on visual acuity, contrast sensitivity, and
      quality of life.
FAU - Wielders, Laura H P
AU  - Wielders LHP
AD  - University Eye Clinic Maastricht UMC+, Maastricht University Medical Center+,
      Maastricht, The Netherlands.
FAU - Schouten, Jan S A G
AU  - Schouten JSAG
FAU - Nuijts, Rudy M M A
AU  - Nuijts RMMA
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Ophthalmol
JT  - Current opinion in ophthalmology
JID - 9011108
RN  - 0 (Anti-Inflammatory Agents)
RN  - 0 (Glucocorticoids)
SB  - IM
MH  - Anti-Inflammatory Agents/*therapeutic use
MH  - Cataract Extraction/*adverse effects
MH  - Glucocorticoids/*therapeutic use
MH  - Humans
MH  - Macular Edema/*prevention & control
MH  - Postoperative Complications/*prevention & control
MH  - Risk Factors
EDAT- 2017/09/16 06:00
MHDA- 2017/12/27 06:00
CRDT- 2017/09/16 06:00
PHST- 2017/09/16 06:00 [pubmed]
PHST- 2017/12/27 06:00 [medline]
PHST- 2017/09/16 06:00 [entrez]
AID - 10.1097/ICU.0000000000000436 [doi]
PST - ppublish
SO  - Curr Opin Ophthalmol. 2018 Jan;29(1):48-53. doi: 10.1097/ICU.0000000000000436.