PMID- 28902719
OWN - NLM
STAT- MEDLINE
DCOM- 20171226
LR  - 20171226
IS  - 1531-7021 (Electronic)
IS  - 1040-8738 (Linking)
VI  - 29
IP  - 1
DP  - 2018 Jan
TI  - Wound closure and tissue adhesives in clear corneal incision cataract surgery.
PG  - 14-18
LID - 10.1097/ICU.0000000000000431 [doi]
AB  - PURPOSE OF REVIEW: Achieving secure wound closure in clear corneal incision
      cataract surgery remains highly desired for its role in reducing infection risk
      and leak-related complications, including hypotony, corneal edema, and lens
      dislocation. Although classic techniques of stromal hydration or wound suturing
      represent traditional approaches, the introduction of newer and more effective
      ocular surface adhesives has increased the options that are available. This
      review aims to provide an update on the peer-reviewed literature regarding wound 
      closure and the currently available and investigational tissue adhesives used to 
      seal clear corneal incisions in cataract surgery. RECENT FINDINGS: Stromal
      hydration and sutured closure of clear corneal incisions remain viable options
      for wound closure. Wound sealants, particularly polyethylene glycol (PEG)-based
      hydrogels, have been found to provide watertight wound seal with less
      foreign-body sensation and surgically induced astigmatism compared with sutures, 
      and less adverse effects and greater ease of use compared with cyanoacrylate and 
      fibrin glues. SUMMARY: Stromal hydration, sutured closure, and use of a corneal
      adhesive are all wound closure options for clear corneal incisions. Of the
      currently available tissue adhesives, PEG hydrogel sealants have become the most 
      widely accepted, with an improved side-effect and biocompatibility profile.
FAU - Tong, Amy Y
AU  - Tong AY
AD  - Department of Ophthalmology, Duke University, Durham, North Carolina, USA.
FAU - Gupta, Preeya K
AU  - Gupta PK
FAU - Kim, Terry
AU  - Kim T
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Ophthalmol
JT  - Current opinion in ophthalmology
JID - 9011108
RN  - 0 (Tissue Adhesives)
SB  - IM
MH  - *Cataract Extraction
MH  - Cornea/surgery
MH  - Humans
MH  - Surgical Wound Dehiscence/*prevention & control
MH  - Tissue Adhesives/*therapeutic use
MH  - *Wound Closure Techniques
MH  - *Wound Healing
EDAT- 2017/09/14 06:00
MHDA- 2017/12/27 06:00
CRDT- 2017/09/14 06:00
PHST- 2017/09/14 06:00 [pubmed]
PHST- 2017/12/27 06:00 [medline]
PHST- 2017/09/14 06:00 [entrez]
AID - 10.1097/ICU.0000000000000431 [doi]
PST - ppublish
SO  - Curr Opin Ophthalmol. 2018 Jan;29(1):14-18. doi: 10.1097/ICU.0000000000000431.