PMID- 28854246
OWN - NLM
STAT- MEDLINE
DCOM- 20171013
LR  - 20181113
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 12
IP  - 8
DP  - 2017
TI  - Non-alcoholic fatty liver disease as a risk factor for female sexual dysfunction 
      in premenopausal women.
PG  - e0182708
LID - 10.1371/journal.pone.0182708 [doi]
AB  - OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) has become a common and
      important chronic liver disease worldwide. Previous studies have indicated that
      NAFLD has an adverse effect on the quality of life, but information is lacking
      about the impact of NAFLD on female sexual dysfunction. The aim of this study was
      to determine the association between NAFLD and female sexual dysfunction in
      premenopausal women. METHODS: This retrospective study consisted of premenopausal
      women who were sexually active and visited the outpatient clinic for a routine
      health check-up between January 2010 and December 2011. Based on the examination 
      of the liver ultrasound scan, the study population was divided into 2 groups:
      cases with NAFLD and normal controls (cases without NAFLD). The female sexual
      function was compared between the two groups of cases. For the assessment of
      sexual function, a female sexual function index (FSFI) questionnaire was used.
      RESULTS: Four hundred seventy women were included, and the prevalence of NAFLD
      and female sexual dysfunction were 67/470 (14.3%) and 238/470 (50.6%),
      respectively. Cases with NAFLD had a lower total FSFI score and higher rate of
      female sexual dysfunction than the normal control [median score of total FSFI
      (interquartile range): 24.7 (21.9-27.8) in NAFLD vs. 26.7 (23.7-29.8) in normal
      control, p<0.005; the female sexual dysfunction: 64.2% in NAFLD vs. 48.4% in
      normal control, p<0.05]. This difference in female sexual dysfunction between the
      two groups remained significant after adjustment. CONCLUSION: NAFLD is associated
      with female sexual dysfunction in premenopausal women.
FAU - Lee, Jae Yeon
AU  - Lee JY
AD  - Department of Obstetrics and Gynecology, Seoul National University College of
      Medicine, Seoul, Korea.
AD  - Department of Obstetrics and Gynecology, Seoul Metropolitan Government Seoul
      National University Boramae Medical Center, Seoul, Korea.
FAU - Shin, Dong Wook
AU  - Shin DW
AD  - Department of Family Medicine, Seoul National University College of Medicine,
      Seoul, Korea.
AD  - Health Promotion Center, Seoul National University Hospital, Seoul, Korea.
AD  - Department of Family Medicine, Samsung Medical Center, Seoul, Korea.
FAU - Oh, Jeong Won
AU  - Oh JW
AD  - Department of Obstetrics and Gynecology, Seoul National University College of
      Medicine, Seoul, Korea.
FAU - Kim, Won
AU  - Kim W
AD  - Department of Internal Medicine, Seoul Metropolitan Government Seoul National
      University Boramae Medical Center, Seoul, Korea.
FAU - Joo, Sae Kyung
AU  - Joo SK
AD  - Department of Internal Medicine, Seoul Metropolitan Government Seoul National
      University Boramae Medical Center, Seoul, Korea.
FAU - Jeon, Myung Jae
AU  - Jeon MJ
AD  - Department of Obstetrics and Gynecology, Seoul National University College of
      Medicine, Seoul, Korea.
FAU - Kim, Sun Min
AU  - Kim SM
AD  - Department of Obstetrics and Gynecology, Seoul National University College of
      Medicine, Seoul, Korea.
AD  - Department of Obstetrics and Gynecology, Seoul Metropolitan Government Seoul
      National University Boramae Medical Center, Seoul, Korea.
AD  - Health Promotion Center, Seoul National University Hospital, Seoul, Korea.
FAU - Yun, Jae Moon
AU  - Yun JM
AD  - Department of Family Medicine, Seoul National University College of Medicine,
      Seoul, Korea.
AD  - Health Promotion Center, Seoul National University Hospital, Seoul, Korea.
FAU - Son, Ki Young
AU  - Son KY
AD  - Department of Family Medicine, Seoul National University College of Medicine,
      Seoul, Korea.
AD  - Health Promotion Center, Seoul National University Hospital, Seoul, Korea.
FAU - Park, Jin Ho
AU  - Park JH
AD  - Department of Family Medicine, Seoul National University College of Medicine,
      Seoul, Korea.
AD  - Health Promotion Center, Seoul National University Hospital, Seoul, Korea.
FAU - Cho, Belong
AU  - Cho B
AD  - Department of Family Medicine, Seoul National University College of Medicine,
      Seoul, Korea.
AD  - Health Promotion Center, Seoul National University Hospital, Seoul, Korea.
FAU - Lee, Seung Mi
AU  - Lee SM
AUID- ORCID: http://orcid.org/0000-0002-2543-0408
AD  - Department of Obstetrics and Gynecology, Seoul National University College of
      Medicine, Seoul, Korea.
AD  - Health Promotion Center, Seoul National University Hospital, Seoul, Korea.
LA  - eng
PT  - Journal Article
DEP - 20170830
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Liver/diagnostic imaging
MH  - Non-alcoholic Fatty Liver Disease/*complications/diagnostic imaging
MH  - *Premenopause
MH  - Quality of Life
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Sexual Dysfunction, Physiological/*etiology
MH  - Surveys and Questionnaires
MH  - Ultrasonography
PMC - PMC5576732
EDAT- 2017/08/31 06:00
MHDA- 2017/10/14 06:00
CRDT- 2017/08/31 06:00
PHST- 2017/03/03 00:00 [received]
PHST- 2017/07/24 00:00 [accepted]
PHST- 2017/08/31 06:00 [entrez]
PHST- 2017/08/31 06:00 [pubmed]
PHST- 2017/10/14 06:00 [medline]
AID - 10.1371/journal.pone.0182708 [doi]
AID - PONE-D-17-08607 [pii]
PST - epublish
SO  - PLoS One. 2017 Aug 30;12(8):e0182708. doi: 10.1371/journal.pone.0182708.
      eCollection 2017.