PMID- 28836174
OWN - NLM
STAT- MEDLINE
DCOM- 20171024
LR  - 20181113
IS  - 1573-2568 (Electronic)
IS  - 0163-2116 (Linking)
VI  - 62
IP  - 10
DP  - 2017 Oct
TI  - Higher Frequency of Nocturnal Blood Pressure Dipping but Not Heart Rate Dipping
      in Inflammatory Bowel Disease.
PG  - 2863-2869
LID - 10.1007/s10620-017-4712-x [doi]
AB  - BACKGROUND: Masked hypertension (MHTN) and lack of nocturnal dipping in blood
      pressure (BP) have been linked to the state of inflammation. AIMS: We aimed to
      assess the frequency of nocturnal patterns of BP and heart rate (HR) in patients 
      with IBD. METHODS: Sixty-three normotensive patients with confirmed IBD during
      remission and 63 healthy subjects were enrolled in a case-control study. All
      subjects were monitored for BP and HR over a period of 24 h under ambulatory
      setting. Means for BP and HR were calculated for nighttime and daytime periods.
      Daytime BP >/= 135/85 mmHg, nighttime BP >/= 120/70 mmHg, and 24-h average BP >/=
      130/80 mmHg were defined as MHTN. The main end points of this study were lack of 
      >10% nocturnal decrease in the systolic BP (NDP-BP) and in HR (NDP-HR). RESULTS: 
      After exclusion of 8 patients with IBD from analysis, 55 patients and 63 control 
      subjects (49% men) with a mean age of 37.5 +/- 11.0 years were enrolled. NDP-BP
      was more common in the IBD group compared to controls (55 vs. 33%; P = 0.026).
      MHTN was detected in 24% of IBD patients compared to 8% among controls (P =
      0.017). Meanwhile, NDP-HR was observed in 22% of the IBD patients and 30% of the 
      control group (P = 0.402). IBD remained a significant predictor of NDP-BP (odds
      ratio 2.60, 95% confidence interval 1.19-5.51) following an adjustment for age
      and gender. CONCLUSIONS: IBD is associated with higher frequency of NDP-BP and
      MHTN; however, nocturnal changes in HR were similar in both groups.
FAU - Pourafkari, Leili
AU  - Pourafkari L
AD  - Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical
      Sciences, Tabriz, Iran.
AD  - Department of Anesthesiology, University at Buffalo, 77 Goodell Street, Suite
      #550, Buffalo, NY, 14203, USA.
FAU - Masnadi-Shirazi, Kourosh
AU  - Masnadi-Shirazi K
AD  - Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical
      Sciences, Tabriz, Iran.
FAU - Taban, Mohammadreza
AU  - Taban M
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz,
      Iran.
FAU - Mohammadi, Solmaz
AU  - Mohammadi S
AD  - Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical
      Sciences, Tabriz, Iran.
FAU - Parizad, Razieh
AU  - Parizad R
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz,
      Iran.
FAU - Ghaffari, Samad
AU  - Ghaffari S
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz,
      Iran.
FAU - Tajlil, Arezou
AU  - Tajlil A
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz,
      Iran.
FAU - Khoshknab, Mir Milad Pourmousavi
AU  - Khoshknab MMP
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz,
      Iran.
FAU - Nader, Nader D
AU  - Nader ND
AD  - Department of Anesthesiology, University at Buffalo, 77 Goodell Street, Suite
      #550, Buffalo, NY, 14203, USA. nnader@buffalo.edu.
LA  - eng
PT  - Journal Article
DEP - 20170823
PL  - United States
TA  - Dig Dis Sci
JT  - Digestive diseases and sciences
JID - 7902782
SB  - AIM
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - *Blood Pressure
MH  - Blood Pressure Monitoring, Ambulatory
MH  - Case-Control Studies
MH  - Chi-Square Distribution
MH  - *Circadian Rhythm
MH  - Female
MH  - Heart Rate
MH  - Humans
MH  - Inflammatory Bowel Diseases/complications/diagnosis/*physiopathology
MH  - Logistic Models
MH  - Male
MH  - Masked Hypertension/diagnosis/etiology/*physiopathology
MH  - Middle Aged
MH  - Odds Ratio
MH  - Prospective Studies
MH  - Risk Factors
MH  - Time Factors
MH  - Young Adult
OTO - NOTNLM
OT  - *Blood pressure
OT  - *Blood pressure monitoring
OT  - *Inflammatory bowel disease
OT  - *Masked hypertension
OT  - *Ulcerative colitis
EDAT- 2017/08/25 06:00
MHDA- 2017/10/25 06:00
CRDT- 2017/08/25 06:00
PHST- 2017/04/28 00:00 [received]
PHST- 2017/08/07 00:00 [accepted]
PHST- 2017/08/25 06:00 [pubmed]
PHST- 2017/10/25 06:00 [medline]
PHST- 2017/08/25 06:00 [entrez]
AID - 10.1007/s10620-017-4712-x [doi]
AID - 10.1007/s10620-017-4712-x [pii]
PST - ppublish
SO  - Dig Dis Sci. 2017 Oct;62(10):2863-2869. doi: 10.1007/s10620-017-4712-x. Epub 2017
      Aug 23.