PMID- 28780072
OWN - NLM
STAT- MEDLINE
DCOM- 20180418
LR  - 20180418
IS  - 1528-0012 (Electronic)
IS  - 0016-5085 (Linking)
VI  - 154
IP  - 2
DP  - 2018 Jan
TI  - Presentation and Epidemiology of Gastroesophageal Reflux Disease.
PG  - 267-276
LID - S0016-5085(17)35977-2 [pii]
LID - 10.1053/j.gastro.2017.07.045 [doi]
AB  - Gastroesophageal reflux disease (GERD) is the most prevalent gastrointestinal
      disorder in the United States, and leads to substantial morbidity, though
      associated mortality is rare. The prevalence of GERD symptoms appeared to
      increase until 1999. Risk factors for complications of GERD include advanced age,
      male sex, white race, abdominal obesity, and tobacco use. Most patients with GERD
      present with heartburn and effortless regurgitation. Coexistent dysphagia is
      considered an alarm symptom, prompting evaluation. There is substantial overlap
      between symptoms of GERD and those of eosinophilic esophagitis, functional
      dyspepsia, and gastroparesis, posing a challenge for patient management.
CI  - Copyright (c) 2018 AGA Institute. Published by Elsevier Inc. All rights reserved.
FAU - Richter, Joel E
AU  - Richter JE
AD  - Joy McCann Culverhouse Center for Swallowing Disorders, Division of Digestive
      Diseases & Nutrition, University of South Florida College of Medicine, Tampa,
      Florida. Electronic address: Jrichte1@health.usf.edu.
FAU - Rubenstein, Joel H
AU  - Rubenstein JH
AD  - Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan;
      Barrett's Esophagus Program, Division of Gastroenterology & Hepatology,
      University of Michigan Medical School, Ann Arbor, Michigan.
LA  - eng
GR  - I01 CX000899/CX/CSRD VA/United States
GR  - U01 CA199336/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Review
DEP - 20170803
PL  - United States
TA  - Gastroenterology
JT  - Gastroenterology
JID - 0374630
SB  - AIM
SB  - IM
MH  - Age Factors
MH  - Biopsy
MH  - Diagnosis, Differential
MH  - Dyspepsia/diagnosis
MH  - Eosinophilic Esophagitis/diagnosis
MH  - Esophageal Neoplasms/diagnosis/etiology
MH  - Esophagitis, Peptic/etiology
MH  - Esophagoscopy
MH  - Female
MH  - Gastroesophageal Reflux/complications/*diagnosis/*epidemiology/etiology
MH  - Gastrointestinal Hemorrhage/etiology
MH  - Gastroparesis/diagnosis
MH  - Heartburn/diagnosis/epidemiology
MH  - Humans
MH  - Male
MH  - Obesity/*epidemiology
MH  - Prevalence
MH  - Quality of Life
MH  - Risk Factors
MH  - Sex Factors
MH  - United States/epidemiology
PMC - PMC5797499
MID - NIHMS897295
OTO - NOTNLM
OT  - *Barrett's Esophagus
OT  - *Erosive Esophagitis
OT  - *Esophageal Stricture
EDAT- 2017/08/07 06:00
MHDA- 2018/04/19 06:00
CRDT- 2017/08/07 06:00
PMCR- 2019/01/01 00:00
PHST- 2017/05/01 00:00 [received]
PHST- 2017/07/18 00:00 [revised]
PHST- 2017/07/18 00:00 [accepted]
PHST- 2019/01/01 00:00 [pmc-release]
PHST- 2017/08/07 06:00 [pubmed]
PHST- 2018/04/19 06:00 [medline]
PHST- 2017/08/07 06:00 [entrez]
AID - S0016-5085(17)35977-2 [pii]
AID - 10.1053/j.gastro.2017.07.045 [doi]
PST - ppublish
SO  - Gastroenterology. 2018 Jan;154(2):267-276. doi: 10.1053/j.gastro.2017.07.045.
      Epub 2017 Aug 3.