PMID- 28648576
OWN - NLM
STAT- MEDLINE
DCOM- 20180822
LR  - 20180822
IS  - 1097-6779 (Electronic)
IS  - 0016-5107 (Linking)
VI  - 87
IP  - 1
DP  - 2018 Jan
TI  - Prior gastroscopy and mortality in patients with gastric cancer: a matched
      retrospective cohort study.
PG  - 119-127.e3
LID - S0016-5107(17)32036-9 [pii]
LID - 10.1016/j.gie.2017.06.013 [doi]
AB  - BACKGROUND AND AIMS: The role of prior gastroscopy on the outcome of patients
      with gastric cancer remains unknown. This study determines the association
      between intervals of prior gastroscopy and mortality in patients with gastric
      cancer. METHODS: We identified 20,066 newly diagnosed patients with gastric
      cancer in the National Health Insurance Database of Taiwan between 2002 and 2007.
      After we excluded patients who had gastroscopies performed </=6 months before the
      diagnosis of cancer, patients were matched into 3 cohorts according to the
      intervals of prior gastroscopy: 6 months to 2 years (<2 Y cohort), 2 to 5 years
      (2-5 Y cohort), and none within the previous 5 years (>5 Y cohort). The 3 cohorts
      were matched for age, curative treatment for gastric cancer, Helicobacter pylori 
      therapy, and propensity scores comprised of sex, comorbidities, and concomitant
      medication usage. The primary outcome is the hazard ratio (HR) of all-cause
      mortality. RESULTS: After matching, we identified 1286, 1286, and 5144 patients
      for the <2 Y, 2 to 5 Y, and >5 Y cohorts. Compared with the >5 Y cohort, the HR
      of all-cause mortality for the <2 Y and 2 to 5 Y cohorts was 0.80 (95% confidence
      interval [CI], 0.72-0.89; P < .001) and 0.83 (95% CI, 0.76-0.91; P < .001),
      respectively. The HRs of gastric cancer-specific mortality were significantly
      lower in the <2 Y (0.80; 95% CI, 0.71-0.91; P < .001) and 2 to 5 Y cohorts (0.83;
      95% CI, 0.75-0.93; P < .001). CONCLUSIONS: Patients with gastric cancer who had a
      gastroscopy performed within 5 years before the cancer diagnosis had
      significantly lower mortality. Our results may support the role of repeat
      endoscopic examination or surveillance endoscopy in selected patients.
CI  - Copyright (c) 2018 American Society for Gastrointestinal Endoscopy. Published by 
      Elsevier Inc. All rights reserved.
FAU - Leung, Wai K
AU  - Leung WK
AD  - Department of Medicine, University of Hong Kong, Hong Kong, China.
FAU - Ho, Hsiu J
AU  - Ho HJ
AD  - Division of Gastroenterology, Taichung Veterans General Hospital, Taichung,
      Taiwan.
FAU - Lin, Jaw-Town
AU  - Lin JT
AD  - School of Medicine, Fu Jen Catholic University, Taipei, Taiwan; Institute of
      Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan.
FAU - Wu, Ming-Shiang
AU  - Wu MS
AD  - Division of Gastroenterology, National Taiwan University Hospital, Taipei,
      Taiwan.
FAU - Wu, Chun-Ying
AU  - Wu CY
AD  - Division of Gastroenterology, Taichung Veterans General Hospital, Taichung,
      Taiwan; Faculty of Medicine and Graduate Institute of Clinical Medicine, National
      Yang-Ming University, Taipei, Taiwan; Department of Public Health and Graduate
      Institute of Clinical Medical Sciences, China Medical University, Taichung,
      Taiwan; National Institute of Cancer Research, National Health Research
      Institutes, Miaoli, Taiwan; Department of Life Sciences and Rong Hsing Research
      Center for Translational Medicine, National Chung-Hsing University, Taichung,
      Taiwan.
LA  - eng
PT  - Journal Article
DEP - 20170623
PL  - United States
TA  - Gastrointest Endosc
JT  - Gastrointestinal endoscopy
JID - 0010505
SB  - IM
CIN - Gastrointest Endosc. 2018 Jan;87(1):128-130. PMID: 29241848
MH  - Adenocarcinoma/*mortality/therapy
MH  - Aged
MH  - Aged, 80 and over
MH  - Cause of Death
MH  - Cohort Studies
MH  - Female
MH  - Gastroscopy/*utilization
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Mortality
MH  - Propensity Score
MH  - Proportional Hazards Models
MH  - Retrospective Studies
MH  - Stomach Neoplasms/*mortality/therapy
MH  - Taiwan
EDAT- 2017/06/27 06:00
MHDA- 2018/08/23 06:00
CRDT- 2017/06/27 06:00
PHST- 2017/03/07 00:00 [received]
PHST- 2017/06/12 00:00 [accepted]
PHST- 2017/06/27 06:00 [pubmed]
PHST- 2018/08/23 06:00 [medline]
PHST- 2017/06/27 06:00 [entrez]
AID - S0016-5107(17)32036-9 [pii]
AID - 10.1016/j.gie.2017.06.013 [doi]
PST - ppublish
SO  - Gastrointest Endosc. 2018 Jan;87(1):119-127.e3. doi: 10.1016/j.gie.2017.06.013.
      Epub 2017 Jun 23.