PMID- 28632793
OWN - NLM
STAT- MEDLINE
DCOM- 20170919
LR  - 20181113
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 12
IP  - 6
DP  - 2017
TI  - The prevalence and correlates of low sexual functioning in women on hemodialysis:
      A multinational, cross-sectional study.
PG  - e0179511
LID - 10.1371/journal.pone.0179511 [doi]
AB  - Sexual dysfunction may affect 80% of women in hemodialysis. However the specific 
      patterns and clinical correlates of sexual functioning remain poorly described.
      The aim of this study was to assess prevalence and correlates of the individual
      domains of sexual functioning in women treated with hemodialysis. We recruited,
      into this multinational cross-sectional study, women treated with long-term
      hemodialysis (Collaborative Working Group on Depression and Sexual dysfunction in
      Hemodialysis study). Self-reported domains of sexual functioning were assessed by
      the Female Sexual Function Index, which is routinely administered within the
      network of dialysis patients followed by the working group. Lower scores
      represented lower sexual functioning. Socio-demographic and clinical correlates
      of each domain of sexual functioning were identified by stepwise multivariable
      linear regression. Sensitivity analyses were restricted to women who reported
      being sexually active. We found that of 1309 enrolled women, 659 (50.3%) provided
      complete responses to FSFI survey questions and 232 (35%) reported being sexually
      active. Overall, most respondents reported either no sexual activity or low
      sexual functioning in all measured domains (orgasm 75.1%; arousal 64.0%;
      lubrication 63.3%; pain 60.7%; satisfaction 60.1%; sexual desire 58.0%).
      Respondents who were waitlisted for a kidney transplant reported scores with
      higher sexual functioning, while older respondents reported scores with lower
      functioning. The presence of depression was associated with worse lubrication and
      pain scores [mean difference for depressed versus non-depressed women (95% CI)
      -0.42 (-0.73 to -0.11), -0.53 (-0.89 to -0.16), respectively] while women who had
      experienced a previous cardiovascular event reported higher pain scores [-0.77
      (-1.40- to -0.13)]. In conclusion, women in hemodialysis reported scores
      consistent with marked low sexual functioning across a range of domains; the low 
      functioning appeared to be associated with comorbidity.
FAU - Saglimbene, Valeria
AU  - Saglimbene V
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
AD  - Sydney School of Public Health, University of Sydney, Sydney, Australia.
FAU - Natale, Patrizia
AU  - Natale P
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Palmer, Suetonia
AU  - Palmer S
AD  - Department of Medicine, University of Otago Christchurch, Christchurch, New
      Zealand.
FAU - Scardapane, Marco
AU  - Scardapane M
AD  - Centre for Outcomes, Research and clinical Epidemiology, Pescara, Italy.
FAU - Craig, Jonathan C
AU  - Craig JC
AD  - Sydney School of Public Health, University of Sydney, Sydney, Australia.
FAU - Ruospo, Marinella
AU  - Ruospo M
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
AD  - Division of Nephrology and Transplantation, Department of Translational Medicine,
      Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.
FAU - Gargano, Letizia
AU  - Gargano L
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Lucisano, Giuseppe
AU  - Lucisano G
AD  - Centre for Outcomes, Research and clinical Epidemiology, Pescara, Italy.
FAU - Torok, Marietta
AU  - Torok M
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Celia, Eduardo
AU  - Celia E
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Gelfman, Ruben
AU  - Gelfman R
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Bednarek-Skublewska, Anna
AU  - Bednarek-Skublewska A
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
AD  - Medical University of Lublin, Lublin, Poland.
FAU - Dulawa, Jan
AU  - Dulawa J
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
AD  - SHS, Medical University of Silesia, Katowice, Poland.
FAU - Stroumza, Paul
AU  - Stroumza P
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Leal, Miguel
AU  - Leal M
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Del Castillo, Domingo
AU  - Del Castillo D
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Murgo, Angelo Marco
AU  - Murgo AM
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Schon, Staffan
AU  - Schon S
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Wollheim, Charlotta
AU  - Wollheim C
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
FAU - Hegbrant, Jorgen
AU  - Hegbrant J
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
AD  - Diaverum Academy, Bari, Italy.
FAU - Strippoli, Giovanni F M
AU  - Strippoli GFM
AD  - Medical Scientific Office, Diaverum, Lund, Sweden.
AD  - Sydney School of Public Health, University of Sydney, Sydney, Australia.
AD  - Diaverum Academy, Bari, Italy.
AD  - Department of Emergency and Organ Transplantation, University of Bari, Bari,
      Italy.
LA  - eng
PT  - Journal Article
DEP - 20170620
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Aged
MH  - Arousal
MH  - Cross-Sectional Studies
MH  - Depression/complications
MH  - Female
MH  - Humans
MH  - Kidney Failure, Chronic/*complications
MH  - Linear Models
MH  - Lubrication
MH  - Middle Aged
MH  - Orgasm
MH  - Prevalence
MH  - Renal Dialysis
MH  - Sexual Behavior
MH  - Sexual Dysfunction, Physiological/complications/*epidemiology
MH  - Surveys and Questionnaires
PMC - PMC5478101
EDAT- 2017/06/21 06:00
MHDA- 2017/09/20 06:00
CRDT- 2017/06/21 06:00
PHST- 2017/02/22 00:00 [received]
PHST- 2017/05/30 00:00 [accepted]
PHST- 2017/06/21 06:00 [entrez]
PHST- 2017/06/21 06:00 [pubmed]
PHST- 2017/09/20 06:00 [medline]
AID - 10.1371/journal.pone.0179511 [doi]
AID - PONE-D-17-07166 [pii]
PST - epublish
SO  - PLoS One. 2017 Jun 20;12(6):e0179511. doi: 10.1371/journal.pone.0179511.
      eCollection 2017.