PMID- 28623004
OWN - NLM
STAT- MEDLINE
DCOM- 20180103
LR  - 20180103
IS  - 1532-8171 (Electronic)
IS  - 0735-6757 (Linking)
VI  - 35
IP  - 12
DP  - 2017 Dec
TI  - Variable methodological quality and use found in systematic reviews referenced in
      STEMI clinical practice guidelines.
PG  - 1828-1835
LID - S0735-6757(17)30449-7 [pii]
LID - 10.1016/j.ajem.2017.06.010 [doi]
AB  - BACKGROUND: The objective of this study was to assess the methodological quality 
      and clarity of reporting of the systematic reviews (SRs) supporting clinical
      practice guideline (CPG) recommendations in the management of ST-elevation
      myocardial infarction (STEMI) across international CPGs. METHODS: We searched 13 
      guideline clearinghouses including the National Guideline Clearinghouse and
      Guidelines International Network (GIN). To meet inclusion criteria CPGs must be
      pertinent to the management of STEMI, endorsed by a governing body or national
      organization, and written in English. We retrieved SRs from the reference
      sections using a combination of keywords and hand searching. Two investigators
      scored eligible SRs using AMSTAR and PRISMA. RESULTS: We included four CPGs. We
      extracted 71 unique SRs. These SRs received AMSTAR scores ranging from 1 (low) to
      9 (high) on an 11-point scale. All CPGs consistently underperformed in areas
      including disclosure of funding sources, risk of bias, and publication bias
      according to AMSTAR. PRISMA checklist completeness ranged from 44% to 96%. The
      PRISMA scores indicated that SRs did not provide a full search strategy, study
      protocol and registration, assessment of publication bias or report funding
      sources. Only one SR was referenced in all four CPGs. All CPGs omitted a large
      subset of available SRs cited by other guidelines. CONCLUSIONS: Our study
      demonstrates the variable quality of SRs used to establish recommendations within
      guidelines included in our sample. Although guideline developers have
      acknowledged this variability, it remains a significant finding that needs to be 
      addressed further. FUNDING: This research did not receive any specific grant from
      funding agencies in the public, commercial, or not-for-profit sectors.
CI  - Copyright (c) 2017 Elsevier Inc. All rights reserved.
FAU - Scott, Jared
AU  - Scott J
AD  - Oklahoma State University Center for Health Sciences College of Osteopathic
      Medicine, 1111 W 17th St, Tulsa, OK 74107, United States. Electronic address:
      jared.t.scott@okstate.edu.
FAU - Howard, Benjamin
AU  - Howard B
AD  - Oklahoma State University Center for Health Sciences College of Osteopathic
      Medicine, 1111 W 17th St, Tulsa, OK 74107, United States. Electronic address:
      benjamin.howard@okstate.edu.
FAU - Sinnett, Philip
AU  - Sinnett P
AD  - Oklahoma State University Center for Health Sciences College of Osteopathic
      Medicine, 1111 W 17th St, Tulsa, OK 74107, United States. Electronic address:
      Philip.sinnet@okstate.edu.
FAU - Schiesel, Michael
AU  - Schiesel M
AD  - Oklahoma State University Medical Center, 744 W 9th St, Tulsa, OK 74127, United
      States. Electronic address: Michael.schiesel@okstate.edu.
FAU - Baker, Jana
AU  - Baker J
AD  - Oklahoma State University Medical Center, 744 W 9th St, Tulsa, OK 74127, United
      States. Electronic address: jana.baker@okstate.edu.
FAU - Henderson, Patrick
AU  - Henderson P
AD  - Oklahoma State University Medical Center, 744 W 9th St, Tulsa, OK 74127, United
      States. Electronic address: patrick.henderson@okstate.edu.
FAU - Vassar, Matt
AU  - Vassar M
AD  - Oklahoma State University Center for Health Sciences College of Osteopathic
      Medicine, 1111 W 17th St, Tulsa, OK 74107, United States. Electronic address:
      matt.vassar@okstate.edu.
LA  - eng
PT  - Journal Article
DEP - 20170615
PL  - United States
TA  - Am J Emerg Med
JT  - The American journal of emergency medicine
JID - 8309942
SB  - IM
MH  - Clinical Protocols
MH  - Evidence-Based Medicine/*standards
MH  - *Guideline Adherence
MH  - Humans
MH  - Periodicals as Topic
MH  - *Practice Guidelines as Topic
MH  - Publication Bias
MH  - Research Design/*standards
MH  - *Review Literature as Topic
MH  - *ST Elevation Myocardial Infarction
MH  - United States
OTO - NOTNLM
OT  - AMSTAR
OT  - Acute coronary syndrome
OT  - Clinical practice guidelines
OT  - PRISMA
OT  - ST-elevated myocardial infarction
OT  - Systematic reviews
EDAT- 2017/06/18 06:00
MHDA- 2018/01/04 06:00
CRDT- 2017/06/18 06:00
PHST- 2017/03/28 00:00 [received]
PHST- 2017/06/03 00:00 [revised]
PHST- 2017/06/05 00:00 [accepted]
PHST- 2017/06/18 06:00 [pubmed]
PHST- 2018/01/04 06:00 [medline]
PHST- 2017/06/18 06:00 [entrez]
AID - S0735-6757(17)30449-7 [pii]
AID - 10.1016/j.ajem.2017.06.010 [doi]
PST - ppublish
SO  - Am J Emerg Med. 2017 Dec;35(12):1828-1835. doi: 10.1016/j.ajem.2017.06.010. Epub 
      2017 Jun 15.