PMID- 28586090
OWN - NLM
STAT- MEDLINE
DCOM- 20180702
LR  - 20180702
IS  - 1932-8737 (Electronic)
IS  - 0160-9289 (Linking)
VI  - 40
IP  - 10
DP  - 2017 Oct
TI  - The association of QRS duration with atrial fibrillation in a heart failure with 
      preserved ejection fraction population: a pilot study.
PG  - 861-864
LID - 10.1002/clc.22736 [doi]
AB  - BACKGROUND: Heart failure is a significant cause of morbidity and mortality, yet 
      patient risk stratification may be difficult. Prevention or treatment of atrial
      fibrillation (AF) may be an important strategy in these patients that could
      positively affect their outcome. It has been demonstrated that in patients with
      systolic dysfunction, prolonged QRS duration (QRSd), an easily measured
      electrocardiographic parameter, is associated with AF. HYPOTHESIS: Prolonged QRSd
      is associated with an increase in prevalence of AF in patients with heart failure
      with preserved ejection fraction(HFPEF). METHODS: Between February 2006 and
      February 2009, 718 patients were discharged with a diagnosis of HF from the
      Dartmouth-Hitchcock Medical Center. Of these, 206 had EF >/=50% by
      echocardiography performed within 72 hours of admission. After exclusions, 82
      patients remained, of which 25 had AF and 57 had sinus rhythm. Characteristics of
      the AF and sinus-rhythm patients were compared in this pilot study. RESULTS:
      After adjustment for age, prior diagnosis of HF, and left atrial area, there was 
      a nonsignificant trend (odds ratio: 2.2, 95% CI of 0.3-17.2) for a QRSd >120 ms
      to be associated with AF. CONCLUSIONS: Similar to results in patients with
      systolic dysfunction, patients with preserved EF may have an association between 
      a prolonged QRSd and AF.
CI  - (c) 2017 Wiley Periodicals, Inc.
FAU - Gigliotti, Joseph N
AU  - Gigliotti JN
AUID- ORCID: http://orcid.org/0000-0003-3628-8811
AD  - Department of Medicine(Cardiology), Dartmouth-Hitchcock Medical Center, Lebanon, 
      New Hampshire.
AD  - Department of Medicine(Cardiology), Geisel School of Medicine at Dartmouth
      College, Hanover, New Hampshire.
FAU - Sidhu, Mandeep S
AU  - Sidhu MS
AD  - Department of Medicine(Cardiology), Albany Medical Center, Albany, New York.
AD  - Department of Medicine(Cardiology), Albany Medical College, Albany, New York.
FAU - Robert, Alina M
AU  - Robert AM
AD  - Department of Medicine(Cardiology), St. Luke's Clinic, Boise, Idaho.
FAU - Zipursky, Jonathan S
AU  - Zipursky JS
AD  - Department of Medicine(Cardiology), University of Toronto, Canada.
FAU - Brown, Jeremiah R
AU  - Brown JR
AD  - Dartmouth Institute for Health Policy and Clinical Practice at the Geisel School 
      of Medicine, Hanover, New Hampshire.
FAU - Costa, Salvatore P
AU  - Costa SP
AD  - Department of Medicine(Cardiology), Dartmouth-Hitchcock Medical Center, Lebanon, 
      New Hampshire.
FAU - Palac, Robert T
AU  - Palac RT
AD  - Department of Medicine(Cardiology), Geisel School of Medicine at Dartmouth
      College, Hanover, New Hampshire.
AD  - Department of Medicine(Cardiology), White River Junction VA Medical Center,
      Vermont.
FAU - Steckman, David A
AU  - Steckman DA
AD  - Department of Medicine(Cardiology), Albany Medical Center, Albany, New York.
AD  - Department of Medicine(Cardiology), Albany Medical College, Albany, New York.
FAU - Malenka, David J
AU  - Malenka DJ
AD  - Department of Medicine(Cardiology), Dartmouth-Hitchcock Medical Center, Lebanon, 
      New Hampshire.
AD  - Department of Medicine(Cardiology), Geisel School of Medicine at Dartmouth
      College, Hanover, New Hampshire.
FAU - Kono, Alan T
AU  - Kono AT
AD  - Department of Medicine(Cardiology), Dartmouth-Hitchcock Medical Center, Lebanon, 
      New Hampshire.
AD  - Department of Medicine(Cardiology), Geisel School of Medicine at Dartmouth
      College, Hanover, New Hampshire.
FAU - Greenberg, Mark L
AU  - Greenberg ML
AD  - Department of Medicine(Cardiology), Dartmouth-Hitchcock Medical Center, Lebanon, 
      New Hampshire.
AD  - Department of Medicine(Cardiology), Geisel School of Medicine at Dartmouth
      College, Hanover, New Hampshire.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20170606
PL  - United States
TA  - Clin Cardiol
JT  - Clinical cardiology
JID - 7903272
SB  - IM
MH  - *Action Potentials
MH  - Aged
MH  - Aged, 80 and over
MH  - Atrial Fibrillation/diagnosis/epidemiology/*physiopathology
MH  - Chi-Square Distribution
MH  - Electrocardiography
MH  - Female
MH  - Heart Conduction System/*physiopathology
MH  - Heart Failure/diagnosis/epidemiology/*physiopathology
MH  - Heart Rate
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - New Hampshire/epidemiology
MH  - Odds Ratio
MH  - Pilot Projects
MH  - Prevalence
MH  - Retrospective Studies
MH  - Risk Factors
MH  - *Stroke Volume
MH  - Time Factors
MH  - *Ventricular Function, Left
OTO - NOTNLM
OT  - QRS Duration
OT  - Atrial Fibrillation
OT  - Diastolic Heart Failure
OT  - Heart Failure
OT  - Heart Failure With Preserved Ejection Fraction
EDAT- 2017/06/07 06:00
MHDA- 2018/07/03 06:00
CRDT- 2017/06/07 06:00
PHST- 2017/02/13 00:00 [received]
PHST- 2017/04/25 00:00 [revised]
PHST- 2017/05/01 00:00 [accepted]
PHST- 2017/06/07 06:00 [pubmed]
PHST- 2018/07/03 06:00 [medline]
PHST- 2017/06/07 06:00 [entrez]
AID - 10.1002/clc.22736 [doi]
PST - ppublish
SO  - Clin Cardiol. 2017 Oct;40(10):861-864. doi: 10.1002/clc.22736. Epub 2017 Jun 6.