PMID- 28570621
OWN - NLM
STAT- MEDLINE
DCOM- 20170928
LR  - 20170928
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 12
IP  - 6
DP  - 2017
TI  - Effect of glaucoma on eye movement patterns and laboratory-based hazard detection
      ability.
PG  - e0178876
LID - 10.1371/journal.pone.0178876 [doi]
AB  - PURPOSE: The mechanisms underlying the elevated crash rates of older drivers with
      glaucoma are poorly understood. A key driving skill is timely detection of
      hazards; however, the hazard detection ability of drivers with glaucoma has been 
      largely unexplored. This study assessed the eye movement patterns and visual
      predictors of performance on a laboratory-based hazard detection task in older
      drivers with glaucoma. METHODS: Participants included 30 older drivers with
      glaucoma (71+/-7 years; average better-eye mean deviation (MD) = -3.1+/-3.2 dB;
      average worse-eye MD = -11.9+/-6.2 dB) and 25 age-matched controls (72+/-7
      years). Visual acuity, contrast sensitivity, visual fields, useful field of view 
      (UFoV; processing speeds), and motion sensitivity were assessed. Participants
      completed a computerised Hazard Perception Test (HPT) while their eye movements
      were recorded using a desk-mounted Tobii TX300 eye-tracking system. The HPT
      comprises a series of real-world traffic videos recorded from the driver's
      perspective; participants responded to road hazards appearing in the videos, and 
      hazard response times were determined. RESULTS: Participants with glaucoma
      exhibited an average of 0.42 seconds delay in hazard response time (p = 0.001),
      smaller saccades (p = 0.010), and delayed first fixation on hazards (p<0.001)
      compared to controls. Importantly, larger saccades were associated with faster
      hazard responses in the glaucoma group (p = 0.004), but not in the control group 
      (p = 0.19). Across both groups, significant visual predictors of hazard response 
      times included motion sensitivity, UFoV, and worse-eye MD (p<0.05). CONCLUSIONS: 
      Older drivers with glaucoma had delayed hazard response times compared to
      controls, with associated changes in eye movement patterns. The association
      between larger saccades and faster hazard response time in the glaucoma group may
      represent a compensatory behaviour to facilitate improved performance.
FAU - Lee, Samantha Sze-Yee
AU  - Lee SS
AUID- ORCID: http://orcid.org/0000-0001-6635-1098
AD  - School of Optometry and Vision Science, Queensland University of Technology,
      Brisbane, Queensland, Australia.
AD  - Institute of Biomedical and Health Innovation, Queensland University of
      Technology, Brisbane, Queensland, Australia.
FAU - Black, Alex A
AU  - Black AA
AD  - School of Optometry and Vision Science, Queensland University of Technology,
      Brisbane, Queensland, Australia.
AD  - Institute of Biomedical and Health Innovation, Queensland University of
      Technology, Brisbane, Queensland, Australia.
FAU - Wood, Joanne M
AU  - Wood JM
AD  - School of Optometry and Vision Science, Queensland University of Technology,
      Brisbane, Queensland, Australia.
AD  - Institute of Biomedical and Health Innovation, Queensland University of
      Technology, Brisbane, Queensland, Australia.
LA  - eng
PT  - Journal Article
DEP - 20170601
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Aged
MH  - Automobile Driving
MH  - Case-Control Studies
MH  - *Eye Movements
MH  - Female
MH  - Glaucoma/*physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
PMC - PMC5453592
EDAT- 2017/06/02 06:00
MHDA- 2017/09/29 06:00
CRDT- 2017/06/02 06:00
PHST- 2017/02/17 00:00 [received]
PHST- 2017/05/20 00:00 [accepted]
PHST- 2017/06/02 06:00 [entrez]
PHST- 2017/06/02 06:00 [pubmed]
PHST- 2017/09/29 06:00 [medline]
AID - 10.1371/journal.pone.0178876 [doi]
AID - PONE-D-17-06633 [pii]
PST - epublish
SO  - PLoS One. 2017 Jun 1;12(6):e0178876. doi: 10.1371/journal.pone.0178876.
      eCollection 2017.