PMID- 28510745
OWN - NLM
STAT- In-Data-Review
LR  - 20180126
IS  - 1471-6771 (Electronic)
IS  - 0007-0912 (Linking)
VI  - 118
IP  - 5
DP  - 2017 May 1
TI  - Neural network imaging to characterize brain injury in cardiac procedures: the
      emerging utility of connectomics.
PG  - 680-688
LID - 10.1093/bja/aex088 [doi]
AB  - Cognitive dysfunction is a poorly understood but potentially devastating
      complication of cardiac surgery. Clinically meaningful assessment of cognitive
      changes after surgery is problematic because of the absence of a means to obtain 
      reproducible, objective, and quantitative measures of the neural disturbances
      that cause altered brain function. By using both structural and functional
      connectivity magnetic resonance imaging data to construct a map of the
      inter-regional connections within the brain, connectomics has the potential to
      increase the specificity and sensitivity of perioperative neurological
      assessment, permitting rational individualized assessment and improvement of
      surgical techniques.
CI  - (c) The Author 2017. Published by Oxford University Press on behalf of the
      British Journal of Anaesthesia. All rights reserved. For Permissions, please
      email: journals.permissions@oup.com.
FAU - Indja, B
AU  - Indja B
AD  - Sydney Translational Imaging Laboratory, Heart Research Institute, Charles
      Perkins Centre, The University of Sydney, NSW, Australia.
AD  - Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.
AD  - The Baird Institute for Applied Heart and Lung Surgical Research, Newtown, NSW,
      Australia.
FAU - Fanning, J P
AU  - Fanning JP
AD  - School of Medicine, The University of Queensland, Herston, Brisbane, Queensland, 
      Australia, General Electric Healthcare, Sydney, NSW, Australia.
AD  - Critical Care Research Group, The Prinice Charles Hospital, Brisbane, Queensland,
      Australia.
FAU - Maller, J J
AU  - Maller JJ
AD  - Sydney Translational Imaging Laboratory, Heart Research Institute, Charles
      Perkins Centre, The University of Sydney, NSW, Australia.
AD  - General Electric Healthcare, Australia.
FAU - Fraser, J F
AU  - Fraser JF
AD  - School of Medicine, The University of Queensland, Herston, Brisbane, Queensland, 
      Australia, General Electric Healthcare, Sydney, NSW, Australia.
AD  - Critical Care Research Group, The Prinice Charles Hospital, Brisbane, Queensland,
      Australia.
FAU - Bannon, P G
AU  - Bannon PG
AD  - Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.
AD  - The Baird Institute for Applied Heart and Lung Surgical Research, Newtown, NSW,
      Australia.
AD  - Institute of Academic Surgery, Royal Prince Alfred Hospital, Camperdown, Sydney, 
      NSW, Australia.
FAU - Vallely, M
AU  - Vallely M
AD  - Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.
AD  - The Baird Institute for Applied Heart and Lung Surgical Research, Newtown, NSW,
      Australia.
AD  - Institute of Academic Surgery, Royal Prince Alfred Hospital, Camperdown, Sydney, 
      NSW, Australia.
FAU - Grieve, S M
AU  - Grieve SM
AD  - Sydney Translational Imaging Laboratory, Heart Research Institute, Charles
      Perkins Centre, The University of Sydney, NSW, Australia.
AD  - Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.
AD  - Department of Radiology, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW,
      Australia.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Br J Anaesth
JT  - British journal of anaesthesia
JID - 0372541
OTO - NOTNLM
OT  - cardiac surgical procedures
OT  - connectome
OT  - coronary artery bypass
OT  - neuroimaging
OT  - off-pump
OT  - postoperative complications
EDAT- 2017/05/17 06:00
MHDA- 2017/05/17 06:00
CRDT- 2017/05/17 06:00
PHST- 2017/05/17 06:00 [entrez]
PHST- 2017/05/17 06:00 [pubmed]
PHST- 2017/05/17 06:00 [medline]
AID - S0007-0912(17)31327-2 [pii]
AID - 10.1093/bja/aex088 [doi]
PST - ppublish
SO  - Br J Anaesth. 2017 May 1;118(5):680-688. doi: 10.1093/bja/aex088.