PMID- 28437003
OWN - NLM
STAT- MEDLINE
DCOM- 20170815
LR  - 20170815
IS  - 1600-0412 (Electronic)
IS  - 0001-6349 (Linking)
VI  - 96
IP  - 6
DP  - 2017 Jun
TI  - High intensity focused ultrasound for the treatment of adenomyosis: selection
      criteria, efficacy, safety and fertility.
PG  - 707-714
LID - 10.1111/aogs.13159 [doi]
AB  - Adenomyosis is a disorder of uterus in which endometrial glands and stroma are
      present within the uterine musculature. The main clinical manifestations are
      dysmenorrhea and menorrhagia. Adenomyosis has a great impact on both the quality 
      of life and fertility of women. The treatment of adenomyosis remains an immense
      challenge. Relevant articles were searched through MEDLINE and PubMed between
      2000 and March 2017. The search terms of adenomyosis, magnetic resonance imaging 
      (MRI) features of adenomyosis, high intensity focused ultrasound (HIFU),
      ultrasound-guided HIFU and MRgFUS were used. There were no language restrictions.
      HIFU is a non-invasive local thermal ablation technique which has been used in
      the treatment of both focal and diffuse adenomyosis. Several case studies have
      demonstrated that HIFU presents low rate of minor and/or major complications and,
      at the same time, a long symptom-relief period. Multiple factors such as the
      enhancement type of the adenomyotic lesion, volume of the adenomyotic lesions,
      number of hyperintense foci on T2WI, location of the uterus, location of
      adenomyotic lesions, thickness of the abdominal wall and distance from the skin
      to the adenomyotic lesions contribute to the efficacy of HIFU. Consequently,
      based on these contributing factors, specific and strict selection criteria have 
      been used to achieve higher efficacy. Thus, patients with pelvic endometriosis,
      adhesions between the bowel and the uterus, or an abdominal surgical scar wider
      than 10 mm, are not suitable for HIFU treatment. Moreover, HIFU-treated patients 
      with adenomyosis, who wished to conceive, showed high conception and live birth
      rates. HIFU is a new and promising treatment option for patients with
      adenomyosis, but its efficacy, safety, cost-effectiveness and fertility outcome
      must be evaluated by randomized controlled trials.
CI  - (c) 2017 Nordic Federation of Societies of Obstetrics and Gynecology.
FAU - Zhang, Lian
AU  - Zhang L
AUID- ORCID: http://orcid.org/0000-0002-1087-679X
AD  - State Key Laboratory of Ultrasound Engineering in Medicine, Chongqing Key
      Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical
      Engineering, Chongqing Medical University, Chongqing, China.
FAU - Rao, Fangwen
AU  - Rao F
AD  - State Key Laboratory of Ultrasound Engineering in Medicine, Chongqing Key
      Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical
      Engineering, Chongqing Medical University, Chongqing, China.
FAU - Setzen, Raymond
AU  - Setzen R
AD  - Department of Obstetrics and Gynecology, Chris Hani Baragwanath Academic
      Hospital, Johannesburg, South Africa.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Acta Obstet Gynecol Scand
JT  - Acta obstetricia et gynecologica Scandinavica
JID - 0370343
SB  - IM
MH  - Adenomyosis/complications/*surgery
MH  - Dysmenorrhea/etiology/*surgery
MH  - Female
MH  - High-Intensity Focused Ultrasound Ablation/*methods
MH  - Humans
MH  - Infertility, Female/etiology/*prevention & control
MH  - Magnetic Resonance Imaging/methods
MH  - Menorrhagia/etiology/*surgery
MH  - Ultrasonography, Interventional/*methods
OTO - NOTNLM
OT  - High intensity focused ultrasound
OT  - adenomyosis
OT  - efficacy
OT  - fertility
OT  - selection criteria
EDAT- 2017/04/25 06:00
MHDA- 2017/08/16 06:00
CRDT- 2017/04/25 06:00
PHST- 2016/12/16 00:00 [received]
PHST- 2017/04/20 00:00 [accepted]
PHST- 2017/04/25 06:00 [pubmed]
PHST- 2017/08/16 06:00 [medline]
PHST- 2017/04/25 06:00 [entrez]
AID - 10.1111/aogs.13159 [doi]
PST - ppublish
SO  - Acta Obstet Gynecol Scand. 2017 Jun;96(6):707-714. doi: 10.1111/aogs.13159.