PMID- 28384559
DCOM- 20171130
LR  - 20181202
IS  - 1872-8227 (Electronic)
IS  - 0168-8227 (Linking)
VI  - 127
DP  - 2017 May
TI  - Neuropathy of type 1 diabetes in the Arab world: A systematic review and
PG  - 172-180
LID - S0168-8227(16)31637-0 [pii]
LID - 10.1016/j.diabres.2017.03.001 [doi]
AB  - AIMS: Although type 1 diabetes (T1D) is a common disease in the Arab nations,
      there is no data available on the prevalence of peripheral neuropathy (PN) among 
      T1D subjects in Arab countries. The aim of this study is to analyze the
      prevalence of PN in T1D subjects via published literature and to draw attention
      to the dearth of the published work in this serious complication of T1D. METHODS:
      A meta-analysis was performed on studies representing different Arab countries
      with a total number of 2243 T1D subjects. RESULTS: The pooled prevalence of PN
      among T1D subjects in the Arab region was estimated as 18% with 95% confidence
      intervals (CI): 0.09-0.34. The PN prevalence was significantly higher in the
      >16-yr age group, with 59.1% (95% CI: 0.45-0.72) compared to 9.5% (95% CI:
      0.05-0.19) in the <16-yr age group. Furthermore, the PN prevalence was
      significantly higher in the group with more than 10-yr T1D, 35% (95% CI:
      0.15-0.62) than in the group with less than 10-yr T1D, 9.4% (95% CI: 0.04-0.21). 
      CONCLUSION: In Arab countries, PN is common in adults and children with T1D, but 
      prevalence varies widely. Older age Arab people (>16years) with T1D are affected 
      more with PN than younger age Arab people (<16years). PN is more frequently
      present in Arab subjects with a longer duration of T1D diabetes than in those
      with shorter duration.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Abdel-Motal, Ussama M
AU  - Abdel-Motal UM
AD  - Sidra Medical and Research Center, Translational Medicine, Qatar Foundation, P.O.
      Box 26999, Doha, Qatar. Electronic address:
FAU - Abdelalim, Essam M
AU  - Abdelalim EM
AD  - Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Qatar
      Foundation, P.O. Box 5825, Doha, Qatar.
FAU - Abou-Saleh, Haissam
AU  - Abou-Saleh H
AD  - Department of Biological and Environmental Sciences, College of Arts and
      Sciences, Qatar University, Doha, Qatar.
FAU - Zayed, Hatem
AU  - Zayed H
AD  - Department of Biomedical Sciences, College of Health Sciences, Qatar University, 
      Doha, Qatar. Electronic address:
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20170322
PL  - Ireland
TA  - Diabetes Res Clin Pract
JT  - Diabetes research and clinical practice
JID - 8508335
SB  - IM
MH  - Adult
MH  - Arab World
MH  - Child
MH  - Diabetes Mellitus, Type 1/*complications/epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Peripheral Nervous System Diseases/*etiology
MH  - Prevalence
MH  - Young Adult
OT  - Arab nations
OT  - Meta-analysis
OT  - Neuropathy
OT  - Peripheral
OT  - Prevalence
OT  - Type 1 diabetes
EDAT- 2017/04/07 06:00
MHDA- 2017/12/01 06:00
CRDT- 2017/04/07 06:00
PHST- 2016/11/22 00:00 [received]
PHST- 2017/01/11 00:00 [revised]
PHST- 2017/03/06 00:00 [accepted]
PHST- 2017/04/07 06:00 [pubmed]
PHST- 2017/12/01 06:00 [medline]
PHST- 2017/04/07 06:00 [entrez]
AID - S0168-8227(16)31637-0 [pii]
AID - 10.1016/j.diabres.2017.03.001 [doi]
PST - ppublish
SO  - Diabetes Res Clin Pract. 2017 May;127:172-180. doi:
      10.1016/j.diabres.2017.03.001. Epub 2017 Mar 22.