PMID- 28383376
OWN - NLM
STAT- MEDLINE
DCOM- 20170710
LR  - 20180714
IS  - 1873-233X (Electronic)
IS  - 0029-7844 (Linking)
VI  - 129
IP  - 5
DP  - 2017 May
TI  - Successful Continuation of Pregnancy After Treatment of Group A Streptococci
      Sepsis.
PG  - 907-910
LID - 10.1097/AOG.0000000000001967 [doi]
AB  - BACKGROUND: Invasive group A streptococci infections in pregnancy have
      historically led to severe maternal and neonatal morbidity and mortality. We are 
      reporting a rare and novel case of successful treatment of third-trimester group 
      A streptococci infection with early, aggressive intervention and maintenance of
      the pregnancy to term. CASE: A 35 year old woman initially presented with fever, 
      flu-like symptoms, and preterm contractions at 34 weeks of gestation. She
      demonstrated signs of early stages of septic shock, ultimately attributed to
      group A streptococci bacteremia. Early, aggressive intervention allowed the
      pregnancy to continue until 38 weeks of gestation with normal maternal and
      neonatal outcomes. CONCLUSION: Early and aggressive treatment of invasive group A
      streptococci infection during pregnancy can potentially avoid severe maternal and
      perinatal morbidity and mortality with a successful continuation of pregnancy.
FAU - Alhousseini, Ali
AU  - Alhousseini A
AD  - Department of Obstetrics and Gynecology, Wayne State University School of
      Medicine, Detroit, Michigan.
FAU - Layne, Mia E
AU  - Layne ME
FAU - Gonik, Bernard
AU  - Gonik B
FAU - Bryant, David
AU  - Bryant D
FAU - Patwardhan, Sanjay
AU  - Patwardhan S
FAU - Patwardhan, Manasi
AU  - Patwardhan M
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Obstet Gynecol
JT  - Obstetrics and gynecology
JID - 0401101
RN  - 0 (Anti-Bacterial Agents)
RN  - 3U02EL437C (Clindamycin)
SB  - AIM
SB  - IM
MH  - Adult
MH  - Anti-Bacterial Agents/administration & dosage/*therapeutic use
MH  - Bacteremia/*diagnosis/drug therapy
MH  - Clindamycin/administration & dosage/*therapeutic use
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Infant, Newborn
MH  - Infusions, Intravenous
MH  - Male
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/*diagnosis/drug therapy
MH  - Pregnancy Trimester, Third
MH  - Prenatal Diagnosis
MH  - Streptococcaceae/*isolation & purification
MH  - Streptococcal Infections/*diagnosis/drug therapy
EDAT- 2017/04/07 06:00
MHDA- 2017/07/14 06:00
CRDT- 2017/04/07 06:00
PHST- 2017/04/07 06:00 [pubmed]
PHST- 2017/07/14 06:00 [medline]
PHST- 2017/04/07 06:00 [entrez]
AID - 10.1097/AOG.0000000000001967 [doi]
PST - ppublish
SO  - Obstet Gynecol. 2017 May;129(5):907-910. doi: 10.1097/AOG.0000000000001967.