PMID- 28099739
OWN - NLM
STAT- MEDLINE
DCOM- 20170516
LR  - 20170516
IS  - 1879-3479 (Electronic)
IS  - 0020-7292 (Linking)
VI  - 136
IP  - 2
DP  - 2017 Feb
TI  - Associations between HIV, highly active anti-retroviral therapy, and hypertensive
      disorders of pregnancy among maternal deaths in South Africa 2011-2013.
PG  - 195-199
LID - 10.1002/ijgo.12038 [doi]
AB  - OBJECTIVE: To explore potential relationships between HIV and highly active
      anti-retroviral therapy (HAART), and hypertensive disorders of pregnancy (HDP).
      METHODS: A retrospective secondary analysis of maternal-deaths data from the
      2011-2013 Saving Mothers Report from South Africa. The incidence of HIV infection
      amongst individuals who died owing to HDP was determined and comparisons were
      made based on HIV status and the use of HAART. RESULTS: Among 4452 maternal
      deaths recorded in the Saving Mothers report, a lower risk of a maternal deaths
      being due to HDP was observed among women who had HIV infections compared with
      women who did not have HIV (relative risk [RR] 0.57, 95% confidence interval [CI]
      0.51-0.64). Further, reduced odds of death being due to HDP were recorded among
      women with AIDS not undergoing HAART compared with women with HIV who did not
      require treatment (RR 0.42, 95% CI 0.3-0.58). Notably, among all women with AIDS,
      a greater risk of death due to HDP was demonstrated among those who received
      HAART compared with those who did not (RR 1.15, 95% CI 1.02-1.29). CONCLUSION:
      HIV and AIDS were associated with a decreased risk of HDP being the primary cause
      of death; the use of HAART increased this risk.
CI  - (c) 2016 International Federation of Gynecology and Obstetrics.
FAU - Sebitloane, Hannah M
AU  - Sebitloane HM
AD  - Discipline of Obstetrics and Gynaecology, Nelson Mandela School of Medicine,
      College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
FAU - Moodley, Jagidesa
AU  - Moodley J
AD  - Women's Health and HIV Research Unit, Discipline of Obstetrics and Gynaecology,
      Nelson Mandela School of Medicine, College of Health Sciences, University of
      KwaZulu-Natal, Durban, South Africa.
FAU - Sartorius, Benn
AU  - Sartorius B
AD  - Discipline of Public Health, School of Nursing and Public Health, College of
      Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
LA  - eng
PT  - Journal Article
DEP - 20161122
PL  - United States
TA  - Int J Gynaecol Obstet
JT  - International journal of gynaecology and obstetrics: the official organ of the
      International Federation of Gynaecology and Obstetrics
JID - 0210174
SB  - IM
MH  - Adult
MH  - *Antiretroviral Therapy, Highly Active
MH  - Female
MH  - HIV Infections/*drug therapy/*epidemiology
MH  - Humans
MH  - *Maternal Mortality
MH  - Pre-Eclampsia/*mortality
MH  - Pregnancy
MH  - Retrospective Studies
MH  - Risk Factors
MH  - South Africa/epidemiology
OTO - NOTNLM
OT  - *HIV infection
OT  - *Highly active anti-retroviral therapy
OT  - *Hypertensive diseases of pregnancy
OT  - *Pre-eclampsia
EDAT- 2017/01/19 06:00
MHDA- 2017/05/17 06:00
CRDT- 2017/01/19 06:00
PHST- 2016/06/27 00:00 [received]
PHST- 2016/09/07 00:00 [revised]
PHST- 2016/11/03 00:00 [accepted]
PHST- 2017/01/19 06:00 [entrez]
PHST- 2017/01/19 06:00 [pubmed]
PHST- 2017/05/17 06:00 [medline]
AID - 10.1002/ijgo.12038 [doi]
PST - ppublish
SO  - Int J Gynaecol Obstet. 2017 Feb;136(2):195-199. doi: 10.1002/ijgo.12038. Epub
      2016 Nov 22.