PMID- 27998009
OWN - NLM
STAT- MEDLINE
DCOM- 20170815
LR  - 20170815
IS  - 1600-0412 (Electronic)
IS  - 0001-6349 (Linking)
VI  - 96
IP  - 6
DP  - 2017 Jun
TI  - Endometriosis-associated infertility: aspects of pathophysiological mechanisms
      and treatment options.
PG  - 659-667
LID - 10.1111/aogs.13082 [doi]
AB  - Endometriosis is a common condition in women of reproductive age. In addition to 
      pain, endometriosis may also reduce fertility. The causes of infertility in women
      with endometriosis may range from anatomical distortions due to adhesions and
      fibrosis to endocrine abnormalities and immunological disturbances. In some
      cases, the various pathophysiological disturbances seem to interact through
      mechanisms so far not fully understood. Whether surgery should be offered as a
      treatment option in endometriosis-associated infertility has become
      controversial, partly due to its modest or undocumented effect. Medical or
      hormonal treatment alone has little or no effect and should only be used in
      conjunction with assisted reproductive technology (ART). Of the various methods
      of ART, intrauterine insemination, due to its simplicity, can be recommended in
      women with minimal or mild peritoneal endometriosis, even though insemination may
      yield a lower success rate than in women without endometriosis. In vitro
      fertilization (IVF) is an effective treatment option in less-advanced disease
      stages, and the success rates are similar to the results in other causes of
      infertility. However, women with more advanced stages of endometriosis have lower
      success rates with IVF.
CI  - (c) 2016 Nordic Federation of Societies of Obstetrics and Gynecology.
FAU - Tanbo, Tom
AU  - Tanbo T
AD  - Department of Reproductive Medicine, Oslo University Hospital, Oslo, Norway.
AD  - Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
FAU - Fedorcsak, Peter
AU  - Fedorcsak P
AD  - Department of Reproductive Medicine, Oslo University Hospital, Oslo, Norway.
AD  - Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20170130
PL  - United States
TA  - Acta Obstet Gynecol Scand
JT  - Acta obstetricia et gynecologica Scandinavica
JID - 0370343
SB  - IM
MH  - Endometriosis/complications/pathology/*therapy
MH  - Female
MH  - Fertilization in Vitro
MH  - Humans
MH  - Infertility, Female/etiology/*therapy
MH  - Insemination, Artificial/methods
MH  - Ovulation Induction/methods
MH  - Pregnancy
MH  - *Reproductive Techniques, Assisted
OTO - NOTNLM
OT  - Endometriosis
OT  - in vitro fertilization
OT  - infertility
OT  - insemination
OT  - surgery
EDAT- 2016/12/21 06:00
MHDA- 2017/08/16 06:00
CRDT- 2016/12/21 06:00
PHST- 2016/10/25 00:00 [received]
PHST- 2016/12/14 00:00 [accepted]
PHST- 2016/12/21 06:00 [pubmed]
PHST- 2017/08/16 06:00 [medline]
PHST- 2016/12/21 06:00 [entrez]
AID - 10.1111/aogs.13082 [doi]
PST - ppublish
SO  - Acta Obstet Gynecol Scand. 2017 Jun;96(6):659-667. doi: 10.1111/aogs.13082. Epub 
      2017 Jan 30.