PMID- 27931571
OWN - NLM
STAT- MEDLINE
DCOM- 20170512
LR  - 20171127
IS  - 1873-2623 (Electronic)
IS  - 0041-1345 (Linking)
VI  - 48
IP  - 10
DP  - 2016 Dec
TI  - Incidence of Diabetes Mellitus After Kidney Transplantation in Slovakia:
      Multicentric, Prospective Analysis.
PG  - 3292-3298
LID - S0041-1345(16)30691-1 [pii]
LID - 10.1016/j.transproceed.2016.09.041 [doi]
AB  - BACKGROUND: The incidence rate of post-transplant diabetes mellitus (PTDM) after 
      kidney transplantation (KT) is 5% to 40%. The objective of this analysis was to
      identify the risk factors of PTDM after KT in the Slovak Republic (SR). METHODS: 
      In the group of 133 patients/non-diabetics, we identified the risk factors of
      PTDM in the monitored period of 12 months from transplantation. RESULTS: The
      incidence of PTDM in the SR in 2014 was 38.3%. By logistic regression, we
      discovered that the age at the time of KT [odds ratio, 1.0885; 95% CI,
      1.0222-1.1592; P = .0082], the value of body mass index (BMI) at the time of KT
      [odds ratio, 1.4606; 95% CI, 1.0099-2.1125; P = .0442], and the value of insulin 
      resistance index (homeostatic model assessment for insulin resistance) at the
      time of KT [odds ratio, 2.5183; 95% CI, 1.7119-3.4692; P < .0001] represented
      predictive factors of PTDM. The independent risk factors of PTDM in our group
      were age at the time of KT of more than 60 years [HR 0.3871; 95% CI
      0.1659-1.7767; P = .0281], waist circumference at the time of KT in men more than
      94 cm and in women more than 80 cm [HR, 3.4833; 95% CI, 1.2789-9.4878 (P =
      .0146)], BMI at the time of KT [HR 3.0011; 95% CI 1.0725-8.3977 (P = .0363)], and
      triacylglycerols at the time of KT more than 1.7 mmol/L [HR, 2.9763; 95% CI,
      1.0141-8.7352; P = .0471]. CONCLUSIONS: In the group of Slovak patients after
      kidney transplantation, the dominating risk factor for PTDM development was
      insulin resistance prior to KT.
CI  - Copyright (c) 2016 Elsevier Inc. All rights reserved.
FAU - Dedinska, I
AU  - Dedinska I
AD  - Surgery Clinic and Transplantation Center, University Hospital in Martin and
      Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
FAU - Baltesova, T
AU  - Baltesova T
AD  - Transplant Department, L. Pasteur's University Hospital, Kosice, Slovak Republic.
FAU - Bena, L
AU  - Bena L
AD  - Transplant Department, L. Pasteur's University Hospital, Kosice, Slovak Republic.
FAU - Cellar, M
AU  - Cellar M
AD  - Department of Transplant Nephrology, II. Internal Clinic of Slovak Medical
      University, F.D. Roosevelt's Faculty Hospital, Banska Bystrica, Slovak Republic.
FAU - Galajda, P
AU  - Galajda P
AD  - I. Internal Clinic, University Hospital Martin and Jessenius Medical Faculty of
      the Comenius University, Martin, Slovak Republic.
FAU - Chrastina, M
AU  - Chrastina M
AD  - Department of Urology and Renal Transplantation Center, University Hospital
      Bratislava and Medical Faculty of the Comenius University, Bratislava, Slovak
      Republic.
FAU - Jurcina, A
AU  - Jurcina A
AD  - Transplant Department, L. Pasteur's University Hospital, Kosice, Slovak Republic.
FAU - Kovacikova, L
AU  - Kovacikova L
AD  - Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
FAU - Laca, L
AU  - Laca L
AD  - Surgery Clinic and Transplantation Center, University Hospital in Martin and
      Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
FAU - Lackova, E
AU  - Lackova E
AD  - Transplant Department, L. Pasteur's University Hospital, Kosice, Slovak Republic.
FAU - Laukova Valachova, S
AU  - Laukova Valachova S
AD  - Surgery Clinic and Transplantation Center, University Hospital in Martin and
      Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
FAU - Miklusica, J
AU  - Miklusica J
AD  - Surgery Clinic and Transplantation Center, University Hospital in Martin and
      Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
      Electronic address: juraj.miklusica@gmail.com.
FAU - Rosenberger, J
AU  - Rosenberger J
AD  - Transplant Department, L. Pasteur's University Hospital, Kosice, Slovak Republic.
FAU - Sersenova, M
AU  - Sersenova M
AD  - Department of Urology and Renal Transplantation Center, University Hospital
      Bratislava and Medical Faculty of the Comenius University, Bratislava, Slovak
      Republic.
FAU - Skalova, P
AU  - Skalova P
AD  - Surgery Clinic and Transplantation Center, University Hospital in Martin and
      Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
FAU - Zilinska, Z
AU  - Zilinska Z
AD  - Department of Urology and Renal Transplantation Center, University Hospital
      Bratislava and Medical Faculty of the Comenius University, Bratislava, Slovak
      Republic.
FAU - Mokan, M
AU  - Mokan M
AD  - I. Internal Clinic, University Hospital Martin and Jessenius Medical Faculty of
      the Comenius University, Martin, Slovak Republic.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
SB  - IM
EIN - Transplant Proc. 2017 Jan - Feb;49(1):237. PMID: 28104148
MH  - Adult
MH  - Age Factors
MH  - Body Mass Index
MH  - Diabetes Mellitus/epidemiology/*etiology
MH  - Female
MH  - Humans
MH  - Incidence
MH  - *Insulin Resistance
MH  - *Kidney Transplantation/adverse effects
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Odds Ratio
MH  - Postoperative Complications/epidemiology
MH  - Prospective Studies
MH  - Risk Factors
MH  - Slovakia
EDAT- 2016/12/10 06:00
MHDA- 2017/05/13 06:00
CRDT- 2016/12/10 06:00
PHST- 2016/07/12 00:00 [received]
PHST- 2016/09/28 00:00 [accepted]
PHST- 2016/12/10 06:00 [entrez]
PHST- 2016/12/10 06:00 [pubmed]
PHST- 2017/05/13 06:00 [medline]
AID - S0041-1345(16)30691-1 [pii]
AID - 10.1016/j.transproceed.2016.09.041 [doi]
PST - ppublish
SO  - Transplant Proc. 2016 Dec;48(10):3292-3298. doi:
      10.1016/j.transproceed.2016.09.041.