PMID- 27898471
DCOM- 20170314
LR  - 20170314
IS  - 1531-7021 (Electronic)
IS  - 1040-8738 (Linking)
VI  - 28
IP  - 2
DP  - 2017 Mar
TI  - Green disease in optical coherence tomography diagnosis of glaucoma.
PG  - 139-153
LID - 10.1097/ICU.0000000000000353 [doi]
AB  - PURPOSE OF REVIEW: Optical coherence tomography (OCT) has become an integral
      component of modern glaucoma practice. Utilizing color codes, OCT analysis has
      rendered glaucoma diagnosis and follow-up simpler and faster for the busy
      clinician. However, green labeling of OCT parameters suggesting normal values may
      confer a false sense of security, potentially leading to missed diagnoses of
      glaucoma and/or glaucoma progression. RECENT FINDINGS: Conditions in which OCT
      color coding may be falsely negative (i.e., green disease) are identified. Early 
      glaucoma in which retinal nerve fiber layer (RNFL) thickness and optic disc
      parameters, albeit labeled green, are asymmetric in both eyes may result in
      glaucoma being undetected. Progressively decreasing RNFL thickness may reveal the
      presence of progressive glaucoma that, because of green labeling, can be missed
      by the clinician. Other ocular conditions that can increase RNFL thickness can
      make the diagnosis of coexisting glaucoma difficult. Recently introduced
      progression analysis features of OCT may help detect green disease. SUMMARY:
      Recognition of green disease is of paramount importance in diagnosing and
      treating glaucoma. Understanding the limitations of imaging technologies coupled 
      with evaluation of serial OCT analyses, prompt clinical examination, and
      structure-function correlation is important to avoid missing real glaucoma
      requiring treatment.
FAU - Sayed, Mohamed S
AU  - Sayed MS
AD  - aBascom Palmer Eye Institute, University of Miami Miller School of Medicine,
      Miami, Florida bCurrent Address: Fillmore Eye Clinic, Alamogordo, New Mexico,
FAU - Margolis, Michael
AU  - Margolis M
FAU - Lee, Richard K
AU  - Lee RK
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Ophthalmol
JT  - Current opinion in ophthalmology
JID - 9011108
SB  - IM
MH  - False Negative Reactions
MH  - Glaucoma/*diagnostic imaging
MH  - Humans
MH  - Intraocular Pressure
MH  - Nerve Fibers/*pathology
MH  - Optic Disk/pathology
MH  - Optic Nerve Diseases/*diagnostic imaging
MH  - Predictive Value of Tests
MH  - Retinal Ganglion Cells/*pathology
MH  - Tomography, Optical Coherence/*standards
EDAT- 2016/11/30 06:00
MHDA- 2017/03/16 06:00
CRDT- 2016/11/30 06:00
PHST- 2016/11/30 06:00 [pubmed]
PHST- 2017/03/16 06:00 [medline]
PHST- 2016/11/30 06:00 [entrez]
AID - 10.1097/ICU.0000000000000353 [doi]
PST - ppublish
SO  - Curr Opin Ophthalmol. 2017 Mar;28(2):139-153. doi: 10.1097/ICU.0000000000000353.