PMID- 27866726
OWN - NLM
STAT- MEDLINE
DCOM- 20170327
LR  - 20170817
IS  - 1879-1883 (Electronic)
IS  - 0002-9610 (Linking)
VI  - 212
IP  - 6
DP  - 2016 Dec
TI  - Trends in mastectomy and reconstruction for breast cancer; a twelve year
      experience from a tertiary care center.
PG  - 1201-1210
LID - S0002-9610(16)30566-9 [pii]
LID - 10.1016/j.amjsurg.2016.08.020 [doi]
AB  - BACKGROUND: Many surgical options exist for breast cancer, including breast
      conserving therapy (BCT), mastectomy with reconstruction (MAST+RECON) or without 
      reconstruction (MAST). Long-term results regarding oncologic outcomes are few and
      primarily retrospective studies. METHODS: A retrospective review of a
      prospectively collected database of patients undergoing breast surgery for breast
      cancer from 2002 to 2014 was performed. Patients were separated into 3 time
      periods for analysis: 2002 to 2005, 2006 to 2009, and 2010 to 2014. Recurrence
      outcomes were compared at 4 years between MAST+RECON patients. RESULTS: Two
      thousand seventy-six patients were identified: 61.2% underwent BCT, 19.7% had
      MAST, and 19.1% had MAST+RECON. BCT patients were older and had smaller tumors.
      MAST+RECON increased in prevalence, whereas BCT decreased. Implant-based
      reconstruction and conservative mastectomy rates increased over the study period.
      Four-year local recurrence-free rates were similar in nipple-sparing and
      skin-sparing mastectomy groups. CONCLUSIONS: BCT usage has decreased, trending
      toward immediate, nipple-sparing mastectomy, implant-based reconstruction.
      Surgeons should be aware of trends to optimally offer patients their surgical
      options.
CI  - Copyright A(c) 2016 Elsevier Inc. All rights reserved.
FAU - Chang, James M
AU  - Chang JM
AD  - Section of Surgical Oncology, Department of Surgery, Mayo Clinic Arizona, 5777 E.
      Mayo Blvd, Phoenix, AZ 85054, USA.
FAU - Kosiorek, Heidi E
AU  - Kosiorek HE
AD  - Department of Biostatistics, Mayo Clinic Arizona, Phoenix, AZ, USA.
FAU - Dueck, Amylou C
AU  - Dueck AC
AD  - Department of Biostatistics, Mayo Clinic Arizona, Phoenix, AZ, USA.
FAU - Casey, William J
AU  - Casey WJ
AD  - Department of Biostatistics, Mayo Clinic Arizona, Phoenix, AZ, USA.
FAU - Rebecca, Alanna M
AU  - Rebecca AM
AD  - Division of Plastic and Reconstructive Surgery, Department of Surgery, Mayo
      Clinic Arizona, Phoenix, AZ, USA.
FAU - Mahabir, Raman
AU  - Mahabir R
AD  - Division of Plastic and Reconstructive Surgery, Department of Surgery, Mayo
      Clinic Arizona, Phoenix, AZ, USA.
FAU - Patel, Samir H
AU  - Patel SH
AD  - Department of Radiation Oncology, Mayo Clinic Arizona, Phoenix, AZ, USA.
FAU - Keole, Sameer R
AU  - Keole SR
AD  - Department of Radiation Oncology, Mayo Clinic Arizona, Phoenix, AZ, USA.
FAU - Wong, William W
AU  - Wong WW
AD  - Department of Radiation Oncology, Mayo Clinic Arizona, Phoenix, AZ, USA.
FAU - Vargas, Carlos E
AU  - Vargas CE
AD  - Department of Radiation Oncology, Mayo Clinic Arizona, Phoenix, AZ, USA.
FAU - Halyard, Michele Y
AU  - Halyard MY
AD  - Department of Radiation Oncology, Mayo Clinic Arizona, Phoenix, AZ, USA.
FAU - Gray, Richard J
AU  - Gray RJ
AD  - Section of Surgical Oncology, Department of Surgery, Mayo Clinic Arizona, 5777 E.
      Mayo Blvd, Phoenix, AZ 85054, USA.
FAU - Wasif, Nabil
AU  - Wasif N
AD  - Section of Surgical Oncology, Department of Surgery, Mayo Clinic Arizona, 5777 E.
      Mayo Blvd, Phoenix, AZ 85054, USA.
FAU - Stucky, Chee-Chee H
AU  - Stucky CH
AD  - Section of Surgical Oncology, Department of Surgery, Mayo Clinic Arizona, 5777 E.
      Mayo Blvd, Phoenix, AZ 85054, USA.
FAU - Pockaj, Barbara A
AU  - Pockaj BA
AD  - Section of Surgical Oncology, Department of Surgery, Mayo Clinic Arizona, 5777 E.
      Mayo Blvd, Phoenix, AZ 85054, USA. Electronic address: pockaj.barbara@mayo.edu.
LA  - eng
PT  - Journal Article
DEP - 20160929
PL  - United States
TA  - Am J Surg
JT  - American journal of surgery
JID - 0370473
SB  - AIM
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Breast Neoplasms/mortality/pathology/*surgery
MH  - Disease-Free Survival
MH  - Female
MH  - Humans
MH  - Mammaplasty/*trends
MH  - Mastectomy/*trends
MH  - Middle Aged
MH  - Neoplasm Recurrence, Local/*epidemiology
MH  - Retrospective Studies
MH  - *Tertiary Care Centers
MH  - Time Factors
MH  - Treatment Outcome
MH  - Young Adult
OTO - NOTNLM
OT  - *Breast cancer
OT  - *Breast conserving therapy
OT  - *Breast reconstruction
OT  - *Mastectomy
EDAT- 2016/11/22 06:00
MHDA- 2017/03/28 06:00
CRDT- 2016/11/22 06:00
PHST- 2016/03/18 00:00 [received]
PHST- 2016/08/23 00:00 [revised]
PHST- 2016/08/23 00:00 [accepted]
PHST- 2016/11/22 06:00 [pubmed]
PHST- 2017/03/28 06:00 [medline]
PHST- 2016/11/22 06:00 [entrez]
AID - S0002-9610(16)30566-9 [pii]
AID - 10.1016/j.amjsurg.2016.08.020 [doi]
PST - ppublish
SO  - Am J Surg. 2016 Dec;212(6):1201-1210. doi: 10.1016/j.amjsurg.2016.08.020. Epub
      2016 Sep 29.