PMID- 27846143
OWN - NLM
STAT- MEDLINE
DCOM- 20180306
LR  - 20180405
IS  - 1536-4828 (Electronic)
IS  - 0885-3177 (Linking)
VI  - 46
IP  - 1
DP  - 2017 Jan
TI  - A Report of 320 Cases of Childhood Pancreatitis: Increasing Incidence, Etiologic 
      Categorization, Dynamics, Severity Assessment, and Outcome.
PG  - 110-115
AB  - OBJECTIVES: Because there is paucity of data on natural history of pediatric
      pancreatitis, we studied prevalence, etiology, severity, and outcome of
      pancreatitis. METHODS: Over 12 years consecutive children with pancreatitis were 
      included. Pancreatitis was classified as acute (AP), acute recurrent (ARP), and
      chronic pancreatitis (CP) as per standard definitions. RESULTS: The study group
      comprised of 320 children (age, 11.4 +/- 3.5 years, 201 males); AP, 160 (50%);
      ARP, 67 (21%); and CP, 93 (29%). The number of cases increased progressively from
      28 to 157 between first and last quarter, and there was a significant increase (r
      = 0.92, P < 0.001) in AP-related hospitalizations over the years. Half of AP were
      idiopathic, 69% had severe pancreatitis (6 died) and on follow-up (21.1 +/- 20.9 
      months) 21.5% progressed to either ARP (n = 8) or CP (n = 24). Progression was
      significantly associated with idiopathic etiology. The majority of ARP (70%) and 
      CP (88%) were idiopathic and on follow-up (23.2 +/- 28.9 months) 22% of ARP
      developed CP. CONCLUSIONS: There was 7-fold increase in number of hospitalization
      due to pancreatitis over the years. Progression of AP to ARP/CP was noted in
      21.5% and ARP to CP in 22%. Thus, a subset of pancreatitis seems to be a
      continuum of acute to ARP and CP.
FAU - Poddar, Ujjal
AU  - Poddar U
AD  - From the Departments of *Pediatric Gastroenterology, and daggerRadiology, Sanjay 
      Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
FAU - Yachha, Surender Kumar
AU  - Yachha SK
FAU - Borkar, Vibhor
AU  - Borkar V
FAU - Srivastava, Anshu
AU  - Srivastava A
FAU - Kumar, Sheo
AU  - Kumar S
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Pancreas
JT  - Pancreas
JID - 8608542
SB  - IM
CIN - Pancreas. 2017 Jul;46(6):e55-e56. PMID: 28609378
MH  - Acute Disease
MH  - Adolescent
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Hospitalization/*statistics & numerical data
MH  - Humans
MH  - Incidence
MH  - India/epidemiology
MH  - Male
MH  - Multivariate Analysis
MH  - Outcome Assessment (Health Care)/methods/statistics & numerical data
MH  - Pancreatitis/epidemiology/pathology/therapy
MH  - Pancreatitis, Chronic/*epidemiology/pathology/therapy
MH  - Prevalence
MH  - *Severity of Illness Index
EDAT- 2016/11/16 06:00
MHDA- 2018/03/07 06:00
CRDT- 2016/11/16 06:00
PHST- 2016/11/16 06:00 [pubmed]
PHST- 2018/03/07 06:00 [medline]
PHST- 2016/11/16 06:00 [entrez]
AID - 10.1097/MPA.0000000000000733 [doi]
PST - ppublish
SO  - Pancreas. 2017 Jan;46(1):110-115. doi: 10.1097/MPA.0000000000000733.