PMID- 27836468
OWN - NLM
STAT- MEDLINE
DCOM- 20170516
LR  - 20170516
IS  - 1879-3479 (Electronic)
IS  - 0020-7292 (Linking)
VI  - 135
IP  - 3
DP  - 2016 Dec
TI  - Outcomes of in vitro fertilization cycles among patients with polycystic ovary
      syndrome following ovarian puncture for in vitro maturation.
PG  - 319-323
LID - S0020-7292(16)30355-1 [pii]
LID - 10.1016/j.ijgo.2016.06.027 [doi]
AB  - OBJECTIVE: To investigate the effects of ovarian puncture for in vitro maturation
      (IVM) on subsequent in vitro fertilization (IVF) embryo transfer cycles in
      patients with polycystic ovary syndrome (PCOS). METHODS: A retrospective study
      included data from patients admitted to the First Affiliated Hospital of Wenzhou 
      Medical University, China, between January 1, 2008 and December 31, 2014.
      Patients with PCOS undergoing IVF cycles after having been treated with IVM
      unsuccessfully were included as the study group and an IVF-procedure data-matched
      control group of patients undergoing their first IVF cycles was included in a 1:4
      ratio. Patients with reproductive anomalies were excluded. Endocrine-hormone
      levels and antral follicle counts were measured and fertilization-related
      outcomes were evaluated. RESULTS: There were 49 patients included in the study
      group and 196 included in the control group. Within the study group, basal
      luteal-hormone, testosterone, and antral follicle count levels were significantly
      lower following IVM treatment. The total gonadotropin dose was lower (P<0.001)
      and the duration of stimulation was shorter (P<0.001) in the study group compared
      with the control group. The clinical-pregnancy rate was higher in the study group
      (P=0.018) and no difference was observed between the groups in ovarian
      hyper-stimulation syndrome (P=0.633). CONCLUSIONS: Previous IVM resulted in
      improved endocrine profiles and increased clinical-pregnancy rates among patients
      with PCOS undergoing IVF cycles.
CI  - Copyright A(c) 2016 International Federation of Gynecology and Obstetrics.
      Published by Elsevier Ireland Ltd. All rights reserved.
FAU - Lin, Jia
AU  - Lin J
AD  - Reproductive Medicine Center, First Affiliated Hospital of Wenzhou Medical
      University, Wenzhou, Zhejiang, China.
FAU - Wang, Peiyu
AU  - Wang P
AD  - Reproductive Medicine Center, First Affiliated Hospital of Wenzhou Medical
      University, Wenzhou, Zhejiang, China.
FAU - Zhao, Junzhao
AU  - Zhao J
AD  - Reproductive Medicine Center, First Affiliated Hospital of Wenzhou Medical
      University, Wenzhou, Zhejiang, China. Electronic address: zjoyce08@sina.com.
FAU - Xiao, Shiquan
AU  - Xiao S
AD  - Reproductive Medicine Center, First Affiliated Hospital of Wenzhou Medical
      University, Wenzhou, Zhejiang, China.
FAU - Yu, Rong
AU  - Yu R
AD  - Reproductive Medicine Center, First Affiliated Hospital of Wenzhou Medical
      University, Wenzhou, Zhejiang, China.
FAU - Jin, Congcong
AU  - Jin C
AD  - Reproductive Medicine Center, First Affiliated Hospital of Wenzhou Medical
      University, Wenzhou, Zhejiang, China.
FAU - Zhu, Ruru
AU  - Zhu R
AD  - Reproductive Medicine Center, First Affiliated Hospital of Wenzhou Medical
      University, Wenzhou, Zhejiang, China.
LA  - eng
PT  - Journal Article
DEP - 20160830
PL  - United States
TA  - Int J Gynaecol Obstet
JT  - International journal of gynaecology and obstetrics: the official organ of the
      International Federation of Gynaecology and Obstetrics
JID - 0210174
RN  - 0 (Gonadotropins)
SB  - IM
MH  - Adult
MH  - China
MH  - Embryo Transfer/*statistics & numerical data
MH  - Female
MH  - *Fertilization in Vitro
MH  - Gonadotropins/*administration & dosage
MH  - Humans
MH  - Infertility, Female/*therapy
MH  - Logistic Models
MH  - Multivariate Analysis
MH  - Ovarian Hyperstimulation Syndrome/epidemiology
MH  - *Ovulation Induction
MH  - Polycystic Ovary Syndrome/*therapy
MH  - Pregnancy
MH  - Pregnancy Rate
MH  - Retrospective Studies
OTO - NOTNLM
OT  - *In vitro fertilization
OT  - *In vitro maturation
OT  - *Ovarian hyper-stimulation syndrome
OT  - *Ovarian puncture
OT  - *Polycystic ovary syndrome
EDAT- 2016/11/12 06:00
MHDA- 2017/05/17 06:00
CRDT- 2016/11/13 06:00
PHST- 2016/02/09 00:00 [received]
PHST- 2016/06/16 00:00 [revised]
PHST- 2016/08/24 00:00 [accepted]
PHST- 2016/11/12 06:00 [pubmed]
PHST- 2017/05/17 06:00 [medline]
PHST- 2016/11/13 06:00 [entrez]
AID - S0020-7292(16)30355-1 [pii]
AID - 10.1016/j.ijgo.2016.06.027 [doi]
PST - ppublish
SO  - Int J Gynaecol Obstet. 2016 Dec;135(3):319-323. doi: 10.1016/j.ijgo.2016.06.027. 
      Epub 2016 Aug 30.