PMID- 27607412
OWN - NLM
STAT- MEDLINE
DCOM- 20170914
LR  - 20170914
IS  - 1346-8138 (Electronic)
IS  - 0385-2407 (Linking)
VI  - 44
IP  - 4
DP  - 2017 Apr
TI  - Usefulness of real-time tissue elastography for detecting the border of basal
      cell carcinomas.
PG  - 438-443
LID - 10.1111/1346-8138.13578 [doi]
AB  - Preoperative evaluation of tumor thickness and silhouette in basal cell carcinoma
      (BCC) is one of the important assessments to be done. However, evaluation is not 
      always sufficient even utilizing sonography and magnetic resonance imaging.
      Recently, a new technique called real-time tissue elastography (RTE) was
      developed that can display the hardness of tissue as a color overlay of a
      sonographic image. Therefore, RTE could be used as a tool for detecting the tumor
      border according to differences in tissue rigidity. In the present study, the
      correlation between histopathological and RTE tumor thickness measurements was
      evaluated for BCC. Eleven BCC (six nodular, three superficial, and two adenoid or
      cystic) from individual patients were evaluated. Tumor silhouette and thickness
      were detected using conventional B-mode sonography and RTE. All lesions were
      surgically excised and tumor thickness was also examined histologically. In the
      six nodular BCC, the tumor silhouette determined by RTE showed a close
      correlation with the results of histopathology. Particularly, for four out of the
      six cases, the correlation was excellent. In addition, the mean difference in
      tumor thickness measurements between histology and RTE (-0.368 mm) was lower than
      that between histology and B-mode sonography (-0.835 mm). As for the superficial 
      BCC, tumor thickness was too thin to evaluate. Tumor thickness measured by B-mode
      sonography and RTE was identical for two cases of adenoid or cystic BCC. In
      conclusion, RTE is useful in the preoperative assessment of tumor thickness,
      especially with the nodular type of BCC, and allows us to determine adequate
      surgical margins.
CI  - (c) 2016 Japanese Dermatological Association.
FAU - Tanaka, Takamitsu
AU  - Tanaka T
AD  - Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.
FAU - Tada, Yayoi
AU  - Tada Y
AD  - Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.
FAU - Ohnishi, Takamitsu
AU  - Ohnishi T
AD  - Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.
FAU - Watanabe, Shinichi
AU  - Watanabe S
AD  - Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.
LA  - eng
PT  - Journal Article
DEP - 20160908
PL  - England
TA  - J Dermatol
JT  - The Journal of dermatology
JID - 7600545
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Carcinoma, Basal Cell/*diagnostic imaging/pathology/surgery
MH  - Elasticity Imaging Techniques/*methods
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Margins of Excision
MH  - Middle Aged
MH  - Preoperative Care/*methods
MH  - Skin Neoplasms/*diagnostic imaging/pathology/surgery
OTO - NOTNLM
OT  - basal cell carcinoma
OT  - elastography
OT  - sonography
OT  - surgical margin
OT  - tumor thickness
EDAT- 2016/09/09 06:00
MHDA- 2017/09/15 06:00
CRDT- 2016/09/09 06:00
PHST- 2016/05/20 00:00 [received]
PHST- 2016/08/02 00:00 [accepted]
PHST- 2016/09/09 06:00 [pubmed]
PHST- 2017/09/15 06:00 [medline]
PHST- 2016/09/09 06:00 [entrez]
AID - 10.1111/1346-8138.13578 [doi]
PST - ppublish
SO  - J Dermatol. 2017 Apr;44(4):438-443. doi: 10.1111/1346-8138.13578. Epub 2016 Sep
      8.