PMID- 27585215
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20161230
IS  - 1531-7021 (Electronic)
IS  - 1040-8738 (Linking)
VI  - 27
IP  - 6
DP  - 2016 Nov
TI  - Ocular manifestations of Stevens-Johnson syndrome and their management.
PG  - 522-529
AB  - PURPOSE OF REVIEW: Recent advances and outcomes data in the management of
      Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) demonstrate the
      need for a universal standard of care for patients admitted with the disease.
      RECENT FINDINGS: Amniotic membrane transplantation, aggressive topical
      corticosteroids, and lubrication in the acute stage are necessary to prevent or
      mitigate long-term ocular sequelae. If chronic ocular disease does occur, several
      interventions can be employed to prevent progressive vision loss and discomfort. 
      The earliest interventions are the ones most likely to prevent chronic
      complications. SUMMARY: The literature overwhelmingly describes acute
      intervention for ocular involvement in SJS/TEN as improving long-term outcomes.
      All patients admitted for SJS/TEN or suspicion of SJS/TEN should be evaluated and
      then closely followed by ophthalmologists. As the disease progresses, the
      interventions needed for visual rehabilitation become more invasive and higher
      risk.
FAU - Saeed, Hajirah N
AU  - Saeed HN
AD  - Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston,
      Massachusetts, USA.
FAU - Chodosh, James
AU  - Chodosh J
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Ophthalmol
JT  - Current opinion in ophthalmology
JID - 9011108
SB  - IM
MH  - Acute Disease
MH  - Chronic Disease
MH  - Eye Diseases/diagnosis/etiology/*therapy
MH  - Humans
MH  - Stevens-Johnson Syndrome/*complications
EDAT- 2016/10/18 06:00
MHDA- 2016/12/15 06:00
CRDT- 2016/09/02 06:00
PHST- 2016/10/18 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
PHST- 2016/09/02 06:00 [entrez]
AID - 10.1097/ICU.0000000000000312 [doi]
PST - ppublish
SO  - Curr Opin Ophthalmol. 2016 Nov;27(6):522-529. doi: 10.1097/ICU.0000000000000312.