PMID- 27580899
OWN - NLM
STAT- MEDLINE
DCOM- 20170117
LR  - 20170117
IS  - 1600-0404 (Electronic)
IS  - 0001-6314 (Linking)
VI  - 134 Suppl 200
DP  - 2016 Sep
TI  - Cumulative evidence for MS as a neural network disconnection syndrome consistent 
      with cognitive impairment mechanisms and the confounding role of fatigue and
      depression-outlook from the Fourth Nordic MS symposium.
PG  - 4-7
LID - 10.1111/ane.12655 [doi]
AB  - The Fourth Nordic MS symposium served as a platform to present an overview over
      the rise and impact of cognitive impairment in people with MS, from early stages 
      on, impairing their quality of life. After discussing MS and cognitive impairment
      symptoms, a review on the pathophysiology underlying cognitive impairment was
      given, followed by a talk on neuroimaging highlighting cortical reorganization in
      MS-affected brains. As a conclusion, therapy and treatment options were
      discussed. The symposium presented several cutting-edge research studies
      providing or testing working models that appear successful in predicting and
      explaining cognitive impairment in MS, such as the disconnection syndrome.
CI  - (c) 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - van Ettinger-Veenstra, H
AU  - van Ettinger-Veenstra H
AD  - Department of Clinical and Experimental Medicine, Linkoping University,
      Linkoping, Sweden.
AD  - Center for Medical Image Science and Visualization (CMIV), Linkoping University, 
      Linkoping, Sweden.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Denmark
TA  - Acta Neurol Scand
JT  - Acta neurologica Scandinavica
JID - 0370336
SB  - IM
MH  - Cognitive Dysfunction/etiology/*physiopathology
MH  - Depression/etiology/*physiopathology
MH  - Fatigue/etiology/*physiopathology
MH  - Humans
MH  - Multiple Sclerosis/complications/*physiopathology
MH  - Nerve Net/*physiopathology
OTO - NOTNLM
OT  - cognition
OT  - cognitive impairment
OT  - connectivity
OT  - disconnection syndrome
OT  - fatigue
OT  - multiple sclerosis
EDAT- 2016/09/02 06:00
MHDA- 2017/01/18 06:00
CRDT- 2016/09/02 06:00
PHST- 2016/07/07 00:00 [accepted]
PHST- 2016/09/02 06:00 [entrez]
PHST- 2016/09/02 06:00 [pubmed]
PHST- 2017/01/18 06:00 [medline]
AID - 10.1111/ane.12655 [doi]
PST - ppublish
SO  - Acta Neurol Scand. 2016 Sep;134 Suppl 200:4-7. doi: 10.1111/ane.12655.