PMID- 27543165
DCOM- 20180212
LR  - 20181203
IS  - 1873-7560 (Electronic)
IS  - 0302-2838 (Linking)
VI  - 71
IP  - 3
DP  - 2017 Mar
TI  - Complications After Systematic, Random, and Image-guided Prostate Biopsy.
PG  - 353-365
LID - S0302-2838(16)30471-7 [pii]
LID - 10.1016/j.eururo.2016.08.004 [doi]
AB  - CONTEXT: Prostate biopsy (PB) represents the gold standard method to confirm the 
      presence of cancer. In addition to traditional random or systematic approaches, a
      magnetic resonance imaging (MRI)-guided technique has been introduced recently.
      OBJECTIVE: To perform a systematic review of complications after transrectal
      ultrasound (TRUS)-guided, transperineal, and MRI-guided PB. EVIDENCE ACQUISITION:
      We performed a systematic literature search of Web of Science, Embase, and Scopus
      databases up to October 2015, according to the Preferred Reporting Items for
      Systematic Reviews and Meta-Analyses (PRISMA) statement. Complications and
      mortality following random, systematic, and image-guided PBs were reviewed.
      Eighty-five references were included. EVIDENCE SYNTHESIS: The most frequent
      complication after PB was minor and self-limiting bleeding (hematuria and
      hematospermia), regardless of the biopsy approach. Occurrence of rectal bleeding 
      was comparable for traditional TRUS-guided and image-guided PBs. Almost 25% of
      patients experienced lower urinary tract symptoms, but only a few had urinary
      retention, with higher rates after a transperineal approach. Temporary erectile
      dysfunction was not negligible, with a return to baseline after 1-6 mo. The
      incidence of infective complications is increasing, with higher rates among men
      with medical comorbidities and older age. Transperineal and in-bore MRI-targeted 
      biopsy may reduce the risk of severe infectious complications. Mortality after PB
      is uncommon, regardless of biopsy technique. CONCLUSIONS: Complications after PB 
      are frequent but often self-limiting. The incidence of hospitalization due to
      severe infections is continuously increasing. The patient's general health
      status, risk factors, and likelihood of antimicrobial resistance should be
      carefully appraised before scheduling a PB. PATIENT SUMMARY: We reviewed the
      variety and incidence of complications after prostate biopsy. Even if frequent,
      complications seldom represent a problem for the patient. The most troublesome
      complications are infections. To minimize this risk, the patient's medical
      condition should be carefully evaluated before biopsy.
CI  - Copyright (c) 2016 European Association of Urology. Published by Elsevier B.V.
      All rights reserved.
FAU - Borghesi, Marco
AU  - Borghesi M
AD  - Department of Urology, University of Bologna, Bologna, Italy; Department of
      Experimental, Diagnostic and Specialty Medicine (DIMES), Cardio-Nephro-Thoracic
      Sciences Doctorate, University of Bologna, Bologna, Italy. Electronic address:
FAU - Ahmed, Hashim
AU  - Ahmed H
AD  - Division of Surgery and Interventional Science, University College London,
      London, UK.
FAU - Nam, Robert
AU  - Nam R
AD  - Division of Urology, Sunnybrook Research Institute, University of Toronto,
      Toronto, Canada.
FAU - Schaeffer, Edward
AU  - Schaeffer E
AD  - The James Buchanan Brady Urological Institute, Johns Hopkins Medical
      Institutions, Baltimore, MD, USA.
FAU - Schiavina, Riccardo
AU  - Schiavina R
AD  - Department of Urology, University of Bologna, Bologna, Italy; Department of
      Experimental, Diagnostic and Specialty Medicine (DIMES), Cardio-Nephro-Thoracic
      Sciences Doctorate, University of Bologna, Bologna, Italy.
FAU - Taneja, Samir
AU  - Taneja S
AD  - Division of Urologic Oncology, Department of Urology, New York University Langone
      Medical Center, New York, NY, USA.
FAU - Weidner, Wolfgang
AU  - Weidner W
AD  - Department of Urology, Pediatric Urology and Andrology, University Clinic of
      Giessen, Giessen, Germany.
FAU - Loeb, Stacy
AU  - Loeb S
AD  - Department of Urology, New York University, New York, NY, USA.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20160817
PL  - Switzerland
TA  - Eur Urol
JT  - European urology
JID - 7512719
SB  - IM
CIN - Eur Urol. 2017 Mar;71(3):366-367. PMID: 27614695
CIN - Eur Urol. 2017 May;71(5):e143-e144. PMID: 28029398
MH  - Biopsy/methods
MH  - Endosonography
MH  - Erectile Dysfunction/epidemiology
MH  - Hematuria/epidemiology
MH  - Hemospermia/epidemiology
MH  - Humans
MH  - Image-Guided Biopsy/*methods
MH  - Lower Urinary Tract Symptoms/epidemiology
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Postoperative Complications/*epidemiology
MH  - Postoperative Hemorrhage/epidemiology
MH  - Prostate/diagnostic imaging/*pathology
MH  - Prostatic Neoplasms/diagnostic imaging/*pathology
MH  - Recovery of Function
MH  - Rectal Diseases/epidemiology
MH  - Surgical Wound Infection/epidemiology
MH  - Urinary Retention/epidemiology
OT  - *Complications
OT  - *Hospitalization
OT  - *Infection
OT  - *MRI-guided biopsy
OT  - *Mortality
OT  - *Prostate biopsy
EDAT- 2016/08/21 06:00
MHDA- 2018/02/13 06:00
CRDT- 2016/08/21 06:00
PHST- 2016/05/08 00:00 [received]
PHST- 2016/08/03 00:00 [accepted]
PHST- 2016/08/21 06:00 [pubmed]
PHST- 2018/02/13 06:00 [medline]
PHST- 2016/08/21 06:00 [entrez]
AID - S0302-2838(16)30471-7 [pii]
AID - 10.1016/j.eururo.2016.08.004 [doi]
PST - ppublish
SO  - Eur Urol. 2017 Mar;71(3):353-365. doi: 10.1016/j.eururo.2016.08.004. Epub 2016
      Aug 17.